128 related articles for article (PubMed ID: 37956909)
1. Branched-chain amino acid catabolic defect in vascular smooth muscle cells drives thoracic aortic dissection via mTOR hyperactivation.
Yu L; Huang T; Zhao J; Zhou Z; Cao Z; Chi Y; Meng S; Huang Y; Xu Y; Xia L; Jiang H; Yin Z; Wang H
Free Radic Biol Med; 2024 Jan; 210():25-41. PubMed ID: 37956909
[TBL] [Abstract][Full Text] [Related]
2. Branched-chain amino acid catabolic defect promotes α-cell proliferation via activating mTOR signaling.
Yang Y; Wang S; Sheng C; Tan J; Chen J; Li T; Ma X; Sun H; Wang X; Zhou L
Mol Cell Endocrinol; 2024 Mar; 582():112143. PubMed ID: 38158148
[TBL] [Abstract][Full Text] [Related]
3. Defective branched chain amino acid catabolism contributes to cardiac dysfunction and remodeling following myocardial infarction.
Wang W; Zhang F; Xia Y; Zhao S; Yan W; Wang H; Lee Y; Li C; Zhang L; Lian K; Gao E; Cheng H; Tao L
Am J Physiol Heart Circ Physiol; 2016 Nov; 311(5):H1160-H1169. PubMed ID: 27542406
[TBL] [Abstract][Full Text] [Related]
4. Cell-autonomous effect of cardiomyocyte branched-chain amino acid catabolism in heart failure in mice.
Yu JY; Cao N; Rau CD; Lee RP; Yang J; Flach RJR; Petersen L; Zhu C; Pak YL; Miller RA; Liu Y; Wang Y; Li Z; Sun H; Gao C
Acta Pharmacol Sin; 2023 Jul; 44(7):1380-1390. PubMed ID: 36991098
[TBL] [Abstract][Full Text] [Related]
5. The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis.
Acevedo A; Jones AE; Danna BT; Turner R; Montales KP; Benincá C; Reue K; Shirihai OS; Stiles L; Wallace M; Wang Y; Bertholet AM; Divakaruni AS
J Biol Chem; 2024 Mar; 300(3):105702. PubMed ID: 38301896
[TBL] [Abstract][Full Text] [Related]
6. Branched-chain ketoacid overload inhibits insulin action in the muscle.
Biswas D; Dao KT; Mercer A; Cowie AM; Duffley L; El Hiani Y; Kienesberger PC; Pulinilkunnil T
J Biol Chem; 2020 Nov; 295(46):15597-15621. PubMed ID: 32878988
[TBL] [Abstract][Full Text] [Related]
7. Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism.
Ferguson D; Eichler SJ; Yiew NKH; Colca JR; Cho K; Patti GJ; Shew TM; Lutkewitte AJ; Mukherjee S; McCommis KS; Niemi NM; Finck BN
Mol Metab; 2023 Apr; 70():101694. PubMed ID: 36801448
[TBL] [Abstract][Full Text] [Related]
8. Branched-chain amino acid transaminase 1 (BCAT1) promotes the growth of breast cancer cells through improving mTOR-mediated mitochondrial biogenesis and function.
Zhang L; Han J
Biochem Biophys Res Commun; 2017 Apr; 486(2):224-231. PubMed ID: 28235484
[TBL] [Abstract][Full Text] [Related]
9. Branched-chain amino acids promote thrombocytopoiesis by activating mTOR signaling.
Jiang H; Zhang L; Yang M; Li G; Ding C; Xin M; Dai J; Sun X; Fan X; Sun H; Liu J; Xu Y
J Thromb Haemost; 2023 Nov; 21(11):3224-3235. PubMed ID: 37473846
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of therapeutic strategies targeting BCAA catabolism using a systems pharmacology model.
Voronova V; Sokolov V; Morias Y; Boezelman MJ; Wågberg M; Henricsson M; Hansson K; Goltsov A; Peskov K; Sundqvist M
Front Pharmacol; 2022; 13():993422. PubMed ID: 36518669
[No Abstract] [Full Text] [Related]
11. High doses of rosuvastatin induce impaired branched-chain amino acid catabolism and lead to insulin resistance.
Bai X; Long X; Song F; Chen B; Sheng C; Tang C; Li L; Zhang J; Zhang R; Zhang J; Li J
Exp Physiol; 2023 Jul; 108(7):961-974. PubMed ID: 37139700
[TBL] [Abstract][Full Text] [Related]
12. Phenylbutyrate, a branched-chain amino acid keto dehydrogenase activator, promotes branched-chain amino acid metabolism and induces muscle catabolism in C2C12 cells.
Crossland H; Smith K; Idris I; Phillips BE; Atherton PJ; Wilkinson DJ
Exp Physiol; 2021 Mar; 106(3):585-592. PubMed ID: 33369803
[TBL] [Abstract][Full Text] [Related]
13. BDK inhibition acts as a catabolic switch to mimic fasting and improve metabolism in mice.
Bollinger E; Peloquin M; Libera J; Albuquerque B; Pashos E; Shipstone A; Hadjipanayis A; Sun Z; Xing G; Clasquin M; Stansfield JC; Tierney B; Gernhardt S; Siddall CP; Greizer T; Geoly FJ; Vargas SR; Gao LC; Williams G; Marshall M; Rosado A; Steppan C; Filipski KJ; Zhang BB; Miller RA; Roth Flach RJ
Mol Metab; 2022 Dec; 66():101611. PubMed ID: 36220546
[TBL] [Abstract][Full Text] [Related]
14. KLF15 maintains contractile phenotype of vascular smooth muscle cells and prevents thoracic aortic dissection by interacting with MRTFB.
Fang G; Tian Y; Huang S; Zhang X; Liu Y; Li Y; Du J; Gao S
J Biol Chem; 2024 May; 300(5):107260. PubMed ID: 38582447
[TBL] [Abstract][Full Text] [Related]
15. Enhanced expression of glucose transporter-1 in vascular smooth muscle cells via the Akt/tuberous sclerosis complex subunit 2 (TSC2)/mammalian target of rapamycin (mTOR)/ribosomal S6 protein kinase (S6K) pathway in experimental renal failure.
Lin CY; Hsu SC; Lee HS; Lin SH; Tsai CS; Huang SM; Shih CC; Hsu YJ
J Vasc Surg; 2013 Feb; 57(2):475-85. PubMed ID: 23265586
[TBL] [Abstract][Full Text] [Related]
16. Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade.
Lu QB; Wan MY; Wang PY; Zhang CX; Xu DY; Liao X; Sun HJ
Redox Biol; 2018 Apr; 14():656-668. PubMed ID: 29175753
[TBL] [Abstract][Full Text] [Related]
17. BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer.
Xue P; Zeng F; Duan Q; Xiao J; Liu L; Yuan P; Fan L; Sun H; Malyarenko OS; Lu H; Xiu R; Liu S; Shao C; Zhang J; Yan W; Wang Z; Zheng J; Zhu F
EBioMedicine; 2017 Jun; 20():50-60. PubMed ID: 28501528
[TBL] [Abstract][Full Text] [Related]
18. Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells.
Lu G; Sun H; She P; Youn JY; Warburton S; Ping P; Vondriska TM; Cai H; Lynch CJ; Wang Y
J Clin Invest; 2009 Jun; 119(6):1678-87. PubMed ID: 19411760
[TBL] [Abstract][Full Text] [Related]
19. Off-target depletion of plasma tryptophan by allosteric inhibitors of BCKDK.
Bowman CE; Neinast MD; Jang C; Patel J; Blair MC; Mirek ET; Jonsson WO; Chu Q; Merlo L; Mandik-Nayak L; Anthony TG; Rabinowitz JD; Arany Z
bioRxiv; 2024 Mar; ():. PubMed ID: 38496495
[TBL] [Abstract][Full Text] [Related]
20. Activation of PKG-CREB-KLF15 by melatonin attenuates Angiotensin II-induced vulnerability to atrial fibrillation via enhancing branched-chain amino acids catabolism.
Yu LM; Dong X; Zhao JK; Xu YL; Xu DY; Xue XD; Zhou ZJ; Huang YT; Zhao QS; Luo LY; Wang ZS; Wang HS
Free Radic Biol Med; 2022 Jan; 178():202-214. PubMed ID: 34864165
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
