BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 37958718)

  • 1. Oncogenic Gαq activates RhoJ through PDZ-RhoGEF.
    Cervantes-Villagrana RD; Color-Aparicio VM; Castillo-Kauil A; García-Jiménez I; Beltrán-Navarro YM; Reyes-Cruz G; Vázquez-Prado J
    Int J Mol Sci; 2023 Oct; 24(21):. PubMed ID: 37958718
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gα
    Castillo-Kauil A; García-Jiménez I; Cervantes-Villagrana RD; Adame-García SR; Beltrán-Navarro YM; Gutkind JS; Reyes-Cruz G; Vázquez-Prado J
    J Biol Chem; 2020 Dec; 295(50):16920-16928. PubMed ID: 33023908
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endothelial cell sprouting driven by RhoJ directly activated by a membrane-anchored Intersectin 1 (ITSN1) RhoGEF module.
    Color-Aparicio VM; Cervantes-Villagrana RD; García-Jiménez I; Beltrán-Navarro YM; Castillo-Kauil A; Escobar-Islas E; Reyes-Cruz G; Vázquez-Prado J
    Biochem Biophys Res Commun; 2020 Mar; 524(1):109-116. PubMed ID: 31980169
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho.
    Fukuhara S; Murga C; Zohar M; Igishi T; Gutkind JS
    J Biol Chem; 1999 Feb; 274(9):5868-79. PubMed ID: 10026210
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Real-time NMR study of guanine nucleotide exchange and activation of RhoA by PDZ-RhoGEF.
    Gasmi-Seabrook GM; Marshall CB; Cheung M; Kim B; Wang F; Jang YJ; Mak TW; Stambolic V; Ikura M
    J Biol Chem; 2010 Feb; 285(8):5137-45. PubMed ID: 20018869
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange factors (GEFs) p115, PDZ-RhoGEF (PRG), and leukemia-associated RhoGEF (LARG).
    Jaiswal M; Gremer L; Dvorsky R; Haeusler LC; Cirstea IC; Uhlenbrock K; Ahmadian MR
    J Biol Chem; 2011 May; 286(20):18202-12. PubMed ID: 21454492
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential.
    Bandekar SJ; Arang N; Tully ES; Tang BA; Barton BL; Li S; Gutkind JS; Tesmer JJG
    Sci Signal; 2019 Feb; 12(569):. PubMed ID: 30783010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival.
    Ding Z; Dhruv H; Kwiatkowska-Piwowarczyk A; Ruggieri R; Kloss J; Symons M; Pirrotte P; Eschbacher JM; Tran NL; Loftus JC
    Neoplasia; 2018 Oct; 20(10):1045-1058. PubMed ID: 30219706
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Detrimental Role of PDZ-RhoGEF in Pathological Cardiac Hypertrophy.
    Huang J; Qu Q; Dai Y; Ren D; Qian J; Ge J
    Hypertension; 2023 Feb; 80(2):403-415. PubMed ID: 36448462
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The molecular basis of RhoA specificity in the guanine nucleotide exchange factor PDZ-RhoGEF.
    Oleksy A; Opaliński Ł; Derewenda U; Derewenda ZS; Otlewski J
    J Biol Chem; 2006 Oct; 281(43):32891-7. PubMed ID: 16954208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
    Pascoe HG; Gutowski S; Chen H; Brautigam CA; Chen Z; Sternweis PC; Zhang X
    Proc Natl Acad Sci U S A; 2015 Dec; 112(48):14852-7. PubMed ID: 26627240
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serotonin signals through postsynaptic Gαq, Trio RhoGEF, and diacylglycerol to promote Caenorhabditis elegans egg-laying circuit activity and behavior.
    Dhakal P; Chaudhry SI; Signorelli R; Collins KM
    Genetics; 2022 Jul; 221(3):. PubMed ID: 35579369
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Preliminary crystallographic analysis of the complex of the human GTPase RhoA with the DH/PH tandem of PDZ-RhoGEF.
    Oleksy A; Barton H; Devedjiev Y; Purdy M; Derewenda U; Otlewski J; Derewenda ZS
    Acta Crystallogr D Biol Crystallogr; 2004 Apr; 60(Pt 4):740-2. PubMed ID: 15039571
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells.
    Oinuma I; Katoh H; Harada A; Negishi M
    J Biol Chem; 2003 Jul; 278(28):25671-7. PubMed ID: 12730235
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetics of recruitment and allosteric activation of ARHGEF25 isoforms by the heterotrimeric G-protein Gαq.
    van Unen J; Yin T; Wu YI; Mastop M; Gadella TW; Goedhart J
    Sci Rep; 2016 Nov; 6():36825. PubMed ID: 27833100
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs).
    Carter AM; Gutowski S; Sternweis PC
    J Biol Chem; 2014 Jul; 289(28):19737-46. PubMed ID: 24855647
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Endothelin A receptor drives invadopodia function and cell motility through the β-arrestin/PDZ-RhoGEF pathway in ovarian carcinoma.
    Semprucci E; Tocci P; Cianfrocca R; Sestito R; Caprara V; Veglione M; Castro VD; Spadaro F; Ferrandina G; Bagnato A; Rosanò L
    Oncogene; 2016 Jun; 35(26):3432-42. PubMed ID: 26522724
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A G
    Slepak VZ; Pronin A
    J Biol Chem; 2020 Dec; 295(50):16929-16930. PubMed ID: 33310745
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.
    Okuhira K; Fitzgerald ML; Tamehiro N; Ohoka N; Suzuki K; Sawada J; Naito M; Nishimaki-Mogami T
    J Biol Chem; 2010 May; 285(21):16369-77. PubMed ID: 20348106
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.
    Booden MA; Siderovski DP; Der CJ
    Mol Cell Biol; 2002 Jun; 22(12):4053-61. PubMed ID: 12024019
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.