BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 37967531)

  • 1. Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis.
    Do MH; Shi W; Ji L; Ladewig E; Zhang X; Srivastava RM; Capistrano KJ; Edwards C; Malik I; Nixon BG; Stamatiades EG; Liu M; Li S; Li P; Chou C; Xu K; Hsu TW; Wang X; Chan TA; Leslie CS; Li MO
    Immunity; 2023 Nov; 56(11):2555-2569.e5. PubMed ID: 37967531
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reprogramming tumour-associated macrophages to outcompete cancer cells.
    Zhang X; Li S; Malik I; Do MH; Ji L; Chou C; Shi W; Capistrano KJ; Zhang J; Hsu TW; Nixon BG; Xu K; Wang X; Ballabio A; Schmidt LS; Linehan WM; Li MO
    Nature; 2023 Jul; 619(7970):616-623. PubMed ID: 37380769
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Upregulation of 6-phosphofructo-2-kinase (PFKFB3) by hyperactivated mammalian target of rapamycin complex 1 is critical for tumor growth in tuberous sclerosis complex.
    Wang Y; Tang S; Wu Y; Wan X; Zhou M; Li H; Zha X
    IUBMB Life; 2020 May; 72(5):965-977. PubMed ID: 31958214
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling.
    Martin P; Wagh V; Reis SA; Erdin S; Beauchamp RL; Shaikh G; Talkowski M; Thiele E; Sheridan SD; Haggarty SJ; Ramesh V
    Mol Autism; 2020; 11(1):2. PubMed ID: 31921404
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mTORC1 enhancement of STIM1-mediated store-operated Ca2+ entry constrains tuberous sclerosis complex-related tumor development.
    Peng H; Liu J; Sun Q; Chen R; Wang Y; Duan J; Li C; Li B; Jing Y; Chen X; Mao Q; Xu KF; Walker CL; Li J; Wang J; Zhang H
    Oncogene; 2013 Sep; 32(39):4702-11. PubMed ID: 23108404
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization.
    Gan B; Sahin E; Jiang S; Sanchez-Aguilera A; Scott KL; Chin L; Williams DA; Kwiatkowski DJ; DePinho RA
    Proc Natl Acad Sci U S A; 2008 Dec; 105(49):19384-9. PubMed ID: 19052232
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway.
    Yang T; Zhu L; Zhai Y; Zhao Q; Peng J; Zhang H; Yang Z; Zhang L; Ding W; Zhao Y
    Cell Mol Immunol; 2016 Sep; 13(5):640-50. PubMed ID: 27593484
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia.
    Wolff NC; Vega-Rubin-de-Celis S; Xie XJ; Castrillon DH; Kabbani W; Brugarolas J
    Mol Cell Biol; 2011 May; 31(9):1870-84. PubMed ID: 21383064
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis.
    Pan H; Zhong XP; Lee S
    BMC Biochem; 2016 Jul; 17(1):14. PubMed ID: 27387347
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.
    Kim SH; Kowalski ML; Carson RP; Bridges LR; Ess KC
    Dis Model Mech; 2013 Jul; 6(4):925-33. PubMed ID: 23580196
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tsc1 is a Critical Regulator of Macrophage Survival and Function.
    Fang C; Yu J; Luo Y; Chen S; Wang W; Zhao C; Sun Z; Wu W; Guo W; Han Z; Hu X; Liao F; Feng X
    Cell Physiol Biochem; 2015; 36(4):1406-18. PubMed ID: 26159807
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of tuberous sclerosis complex 1 in regulating innate immunity.
    Pan H; O'Brien TF; Zhang P; Zhong XP
    J Immunol; 2012 Apr; 188(8):3658-66. PubMed ID: 22412198
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors.
    Huang J; Wu S; Wu CL; Manning BD
    Cancer Res; 2009 Aug; 69(15):6107-14. PubMed ID: 19602587
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.
    Di Nardo A; Wertz MH; Kwiatkowski E; Tsai PT; Leech JD; Greene-Colozzi E; Goto J; Dilsiz P; Talos DM; Clish CB; Kwiatkowski DJ; Sahin M
    Hum Mol Genet; 2014 Jul; 23(14):3865-74. PubMed ID: 24599401
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response.
    Babcock JT; Nguyen HB; He Y; Hendricks JW; Wek RC; Quilliam LA
    J Biol Chem; 2013 May; 288(22):15687-98. PubMed ID: 23612979
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hyperactivation of mammalian target of rapamycin complex 1 (mTORC1) promotes breast cancer progression through enhancing glucose starvation-induced autophagy and Akt signaling.
    Chen Y; Wei H; Liu F; Guan JL
    J Biol Chem; 2014 Jan; 289(2):1164-73. PubMed ID: 24275666
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tumor suppressors TSC1 and TSC2 differentially modulate actin cytoskeleton and motility of mouse embryonic fibroblasts.
    Goncharova EA; James ML; Kudryashova TV; Goncharov DA; Krymskaya VP
    PLoS One; 2014; 9(10):e111476. PubMed ID: 25360538
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel Hap1-Tsc1 interaction regulates neuronal mTORC1 signaling and morphogenesis in the brain.
    Mejia LA; Litterman N; Ikeuchi Y; de la Torre-Ubieta L; Bennett EJ; Zhang C; Harper JW; Bonni A
    J Neurosci; 2013 Nov; 33(46):18015-21. PubMed ID: 24227713
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension.
    Houssaini A; Abid S; Derumeaux G; Wan F; Parpaleix A; Rideau D; Marcos E; Kebe K; Czibik G; Sawaki D; Treins C; Dubois-Randé JL; Li Z; Amsellem V; Lipskaia L; Pende M; Adnot S
    Am J Respir Cell Mol Biol; 2016 Sep; 55(3):352-67. PubMed ID: 26991739
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway.
    Yoshida S; Hong S; Suzuki T; Nada S; Mannan AM; Wang J; Okada M; Guan KL; Inoki K
    J Biol Chem; 2011 Sep; 286(37):32651-60. PubMed ID: 21784859
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.