BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 37971069)

  • 1. Design, synthesis of novel chromene-based scaffolds targeting hepatocellular carcinoma: Cell cycle arrest, cytotoxic effect against resistant cancer cells, apoptosis induction, and c-Src inhibition.
    Abdelall EKA; Elshemy HAH; Labib MB; Mohamed FEA
    Drug Dev Res; 2024 Feb; 85(1):e22133. PubMed ID: 37971069
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of novel heterocyclic compounds based on 4-aryl-4H-chromene scaffold as anticancer agents: Design, synthesis, antiprofilerative activity against resistant cancer cells, dual β-tubulin/c-Src inhibition, cell cycle arrest and apoptosis induction.
    Abdelall EKA; A H Elshemy H; Labib MB; E A Mohamed F
    Bioorg Chem; 2022 Mar; 120():105591. PubMed ID: 34998122
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel pyrazole-based COX-2 inhibitors as potential anticancer agents: Design, synthesis, cytotoxic effect against resistant cancer cells, cell cycle arrest, apoptosis induction and dual EGFR/Topo-1 inhibition.
    Halim PA; Sharkawi SMZ; Labib MB
    Bioorg Chem; 2023 Feb; 131():106273. PubMed ID: 36444790
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analogue based drug design, synthesis, molecular docking and anticancer evaluation of novel chromene sulfonamide hybrids as aromatase inhibitors and apoptosis enhancers.
    Ghorab MM; Alsaid MS; Al-Ansary GH; Abdel-Latif GA; Abou El Ella DA
    Eur J Med Chem; 2016 Nov; 124():946-958. PubMed ID: 27770735
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo[h]chromene.
    Alblewi FF; Okasha RM; Hritani ZM; Mohamed HM; El-Nassag MAA; Halawa AH; Mora A; Fouda AM; Assiri MA; Al-Dies AM; Afifi TH; El-Agrody AM
    Bioorg Chem; 2019 Jun; 87():560-571. PubMed ID: 30928878
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of novel hybrids targeting mTOR and HDACs for potential treatment of hepatocellular carcinoma.
    Zhai S; Zhang H; Chen R; Wu J; Ai D; Tao S; Cai Y; Zhang JQ; Wang L
    Eur J Med Chem; 2021 Dec; 225():113824. PubMed ID: 34509167
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of new series of hexahydroquinoline and fused quinoline derivatives as potent inhibitors of wild-type EGFR and mutant EGFR (L858R and T790M).
    Shaheen MA; El-Emam AA; El-Gohary NS
    Bioorg Chem; 2020 Dec; 105():104274. PubMed ID: 33339080
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and molecular docking studies of thymol based 1,2,3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast cancer cells.
    Alam MM; Malebari AM; Syed N; Neamatallah T; Almalki ASA; Elhenawy AA; Obaid RJ; Alsharif MA
    Bioorg Med Chem; 2021 May; 38():116136. PubMed ID: 33894490
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines.
    Badawi WA; Samir M; Fathy HM; Okda TM; Noureldin MH; Atwa GMK; AboulWafa OM
    Bioorg Chem; 2023 Sep; 138():106610. PubMed ID: 37210828
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of potential anticancer agents and apoptotic inducers based on 4-aryl-4H chromene scaffold: Design, synthesis, biological evaluation and insight on their proliferation inhibition mechanism.
    Elshemy HAH; Zaki MA; Mahmoud AM; Khan SI; Chittiboyina AG; Kamal AM
    Bioorg Chem; 2022 Jan; 118():105475. PubMed ID: 34800886
    [TBL] [Abstract][Full Text] [Related]  

  • 11. meta-Ureidophenoxy-1,2,3-triazole hybrid as a novel scaffold for promising HepG2 hepatocellular carcinoma inhibitors: Synthesis, biological evaluation and molecular docking studies.
    Limpachayaporn P; Nuchpun S; Sirirak J; Charoensuksai P; Wongprayoon P; Chuaypen N; Tangkijvanich P; Suksamrarn A
    Bioorg Med Chem; 2022 Nov; 74():117048. PubMed ID: 36270111
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
    Qin J; Qu S; Zhu K; Cheng Y; Pan G; Jing W; Liu X; Sun X; Liu L
    Bioorg Med Chem; 2021 Feb; 32():116003. PubMed ID: 33461148
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones.
    Mohamed MF; Hassaneen HM; Abdelhamid IA
    Eur J Med Chem; 2018 Jan; 143():532-541. PubMed ID: 29207336
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New proapoptotic chemotherapeutic agents based on the quinolone-3-carboxamide scaffold acting by VEGFR-2 inhibition.
    El-Fakharany ZS; Nissan YM; Sedky NK; Arafa RK; Abou-Seri SM
    Sci Rep; 2023 Jul; 13(1):11346. PubMed ID: 37443185
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study.
    AboulWafa OM; Daabees HMG; Badawi WA
    Bioorg Chem; 2020 Jun; 99():103798. PubMed ID: 32247112
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis.
    Mohamed TK; Batran RZ; Elseginy SA; Ali MM; Mahmoud AE
    Bioorg Chem; 2019 Apr; 85():253-273. PubMed ID: 30641320
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, molecular docking, in vitro, and in vivo studies of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors with potential activity against hepatocellular carcinoma.
    Eissa IH; Ibrahim MK; Metwaly AM; Belal A; Mehany ABM; Abdelhady AA; Elhendawy MA; Radwan MM; ElSohly MA; Mahdy HA
    Bioorg Chem; 2021 Feb; 107():104532. PubMed ID: 33334586
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, molecular docking and cytotoxic evaluation of novel 2-furybenzimidazoles as VEGFR-2 inhibitors.
    Abdullaziz MA; Abdel-Mohsen HT; El Kerdawy AM; Ragab FAF; Ali MM; Abu-Bakr SM; Girgis AS; El Diwani HI
    Eur J Med Chem; 2017 Aug; 136():315-329. PubMed ID: 28505536
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel 2-Sulfanylquinazolin-4(3
    Altharawi A; Alanazi MM; Alossaimi MA; Alanazi AS; Alqahtani SM; Geesi MH; Riadi Y
    Molecules; 2023 Jul; 28(14):. PubMed ID: 37513420
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity.
    ElZahabi HSA; Nafie MS; Osman D; Elghazawy NH; Soliman DH; El-Helby AAH; Arafa RK
    Eur J Med Chem; 2021 Oct; 222():113609. PubMed ID: 34119830
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.