BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 37971069)

  • 21. Nicotinonitrile-derived apoptotic inducers: Design, synthesis, X-ray crystal structure and Pim kinase inhibition.
    Aboukhatwa SM; Ibrahim AO; Aoyama H; Al-Behery AS; Shaldam MA; El-Ashmawy G; Tawfik HO
    Bioorg Chem; 2022 Dec; 129():106126. PubMed ID: 36108589
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers.
    Sherbiny FF; Bayoumi AH; El-Morsy AM; Sobhy M; Hagras M
    Bioorg Chem; 2021 Nov; 116():105325. PubMed ID: 34507234
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
    Mohamed MF; Hassaneen HM; Elzayat EM; El-Hallouty SM; El-Manawaty M; Saleh FM; Mohamed Y; El-Zohiry D; Fahmy G; Abdelaal N; Hassanin N; Hossam N
    Anticancer Agents Med Chem; 2019; 19(9):1141-1149. PubMed ID: 30843494
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Design, synthesis, and antitumor activity of novel compounds based on 1,2,4-triazolophthalazine scaffold: Apoptosis-inductive and PCAF-inhibitory effects.
    Turky A; Bayoumi AH; Ghiaty A; El-Azab AS; A-M Abdel-Aziz A; Abulkhair HS
    Bioorg Chem; 2020 Aug; 101():104019. PubMed ID: 32615465
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Dual EGFR/VEGFR2 inhibitors and apoptosis inducers: Synthesis and antitumor activity of novel pyrazoline derivatives.
    Alkamaly OM; Altwaijry N; Sabour R; Harras MF
    Arch Pharm (Weinheim); 2021 Apr; 354(4):e2000351. PubMed ID: 33252142
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Design, synthesis, biological evaluation, and modeling studies of novel conformationally-restricted analogues of sorafenib as selective kinase-inhibitory antiproliferative agents against hepatocellular carcinoma cells.
    Sbenati RM; Zaraei SO; El-Gamal MI; Anbar HS; Tarazi H; Zoghbor MM; Mohamood NA; Khakpour MM; Zaher DM; Omar HA; Alach NN; Shehata MK; El-Gamal R
    Eur J Med Chem; 2021 Jan; 210():113081. PubMed ID: 33310290
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Discovery of PIM-1 kinase inhibitors based on the 2,5-disubstituted 1,3,4-oxadiazole scaffold against prostate cancer: Design, synthesis, in vitro and in vivo cytotoxicity investigation.
    Castanet AS; Nafie MS; Said SA; Arafa RK
    Eur J Med Chem; 2023 Mar; 250():115220. PubMed ID: 36848846
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Discovery of 5-aryl-3-thiophen-2-yl-1H-pyrazoles as a new class of Hsp90 inhibitors in hepatocellular carcinoma.
    Mohamady S; Ismail MI; Mogheith SM; Attia YM; Taylor SD
    Bioorg Chem; 2020 Jan; 94():103433. PubMed ID: 31785857
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
    Li B; Zhu F; He F; Huang Q; Liu X; Wu T; Zhao T; Qiu Y; Wu Z; Xue Y; Fang M
    Bioorg Chem; 2020 Mar; 96():103592. PubMed ID: 32044517
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Design, synthesis and in vitro antitumor activity of novel N-substituted-4-phenyl/benzylphthalazin-1-ones.
    Eldehna WM; Ibrahim HS; Abdel-Aziz HA; Farrag NN; Youssef MM
    Eur J Med Chem; 2015 Jan; 89():549-60. PubMed ID: 25462265
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy.
    Ibrahim TS; Hawwas MM; Taher ES; Alhakamy NA; Alfaleh MA; Elagawany M; Elgendy B; Zayed GM; Mohamed MFA; Abdel-Samii ZK; Elshaier YAMM
    Bioorg Chem; 2020 Dec; 105():104352. PubMed ID: 33080494
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, synthesis and biological evaluation of novel 1,3,4-trisubstituted pyrazole derivatives as potential chemotherapeutic agents for hepatocellular carcinoma.
    Harras MF; Sabour R
    Bioorg Chem; 2018 Aug; 78():149-157. PubMed ID: 29567429
    [TBL] [Abstract][Full Text] [Related]  

  • 33. New brefeldin A-cinnamic acid ester derivatives as potential antitumor agents: Design, synthesis and biological evaluation.
    Jiang YY; Wu S; Wu YW; Gao Y; Chong D; Sun C; Wei MY; Gu YC; Shao CL; Gu Y
    Eur J Med Chem; 2022 Oct; 240():114598. PubMed ID: 35849940
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Discovery of penipanoid C-inspired 2-(3,4,5-trimethoxybenzoyl)quinazolin-4(3H)-one derivatives as potential anticancer agents by inhibiting cell proliferation and inducing apoptosis in hepatocellular carcinoma cells.
    Wang CJ; Guo X; Zhai RQ; Sun C; Xiao G; Chen J; Wei MY; Shao CL; Gu Y
    Eur J Med Chem; 2021 Nov; 224():113671. PubMed ID: 34237623
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design, synthesis, and antitumor screening of new thiazole, thiazolopyrimidine, and thiazolotriazine derivatives as potent inhibitors of VEGFR-2.
    Abd Elhameed AA; Ali AR; Ghabbour HA; Bayomi SM; El-Gohary NS
    Drug Dev Res; 2023 Dec; 84(8):1664-1698. PubMed ID: 37661648
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking.
    Eldehna WM; Fares M; Ibrahim HS; Aly MH; Zada S; Ali MM; Abou-Seri SM; Abdel-Aziz HA; Abou El Ella DA
    Eur J Med Chem; 2015 Jul; 100():89-97. PubMed ID: 26071861
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Novel benzotriazole N-acylarylhydrazone hybrids: Design, synthesis, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and FAK inhibition.
    Kassab AE; Hassan RA
    Bioorg Chem; 2018 Oct; 80():531-544. PubMed ID: 30014921
    [TBL] [Abstract][Full Text] [Related]  

  • 38. 4-Aryl-4H-chromene-3-carbonitrile derivatives: evaluation of Src kinase inhibitory and anticancer activities.
    Fallah-Tafti A; Tiwari R; Shirazi AN; Akbarzadeh T; Mandal D; Shafiee A; Parang K; Foroumadi A
    Med Chem; 2011 Sep; 7(5):466-72. PubMed ID: 21801146
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design and synthesis of parthenolide and 5-fluorouracil conjugates as potential anticancer agents against drug resistant hepatocellular carcinoma.
    Ding Y; Li S; Ge W; Liu Z; Zhang X; Wang M; Chen T; Chen Y; Zhang Q
    Eur J Med Chem; 2019 Dec; 183():111706. PubMed ID: 31553932
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design, synthesis, modeling studies and biological evaluation of pyrazole derivatives linked to oxime and nitrate moieties as nitric oxide donor selective COX-2 and aromatase inhibitors with dual anti-inflammatory and anti-neoplastic activities.
    A A Fadaly W; A M M Elshaier Y; T M Nemr M; R A Abdellatif K
    Bioorg Chem; 2023 May; 134():106428. PubMed ID: 36893546
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.