These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

500 related articles for article (PubMed ID: 37974279)

  • 1. Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition.
    Pelaez MC; Desmeules A; Gelon PA; Glasson B; Marcadet L; Rodgers A; Phaneuf D; Pozzi S; Dutchak PA; Julien JP; Sephton CF
    Acta Neuropathol Commun; 2023 Nov; 11(1):182. PubMed ID: 37974279
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms.
    Wächter N; Storch A; Hermann A
    Amyotroph Lateral Scler Frontotemporal Degener; 2015; 16(7-8):431-41. PubMed ID: 26174443
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma.
    Shiihashi G; Ito D; Arai I; Kobayashi Y; Hayashi K; Otsuka S; Nakajima K; Yuzaki M; Itohara S; Suzuki N
    EBioMedicine; 2017 Oct; 24():102-115. PubMed ID: 28928015
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.
    López-Erauskin J; Tadokoro T; Baughn MW; Myers B; McAlonis-Downes M; Chillon-Marinas C; Asiaban JN; Artates J; Bui AT; Vetto AP; Lee SK; Le AV; Sun Y; Jambeau M; Boubaker J; Swing D; Qiu J; Hicks GG; Ouyang Z; Fu XD; Tessarollo L; Ling SC; Parone PA; Shaw CE; Marsala M; Lagier-Tourenne C; Cleveland DW; Da Cruz S
    Neuron; 2018 Nov; 100(4):816-830.e7. PubMed ID: 30344044
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha.
    Kia A; McAvoy K; Krishnamurthy K; Trotti D; Pasinelli P
    Glia; 2018 May; 66(5):1016-1033. PubMed ID: 29380416
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting TNFα produced by astrocytes expressing amyotrophic lateral sclerosis-linked mutant fused in sarcoma prevents neurodegeneration and motor dysfunction in mice.
    Jensen BK; McAvoy KJ; Heinsinger NM; Lepore AC; Ilieva H; Haeusler AR; Trotti D; Pasinelli P
    Glia; 2022 Jul; 70(7):1426-1449. PubMed ID: 35474517
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS.
    Xia R; Liu Y; Yang L; Gal J; Zhu H; Jia J
    Mol Neurodegener; 2012 Mar; 7():10. PubMed ID: 22443542
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.
    Verbeeck C; Deng Q; Dejesus-Hernandez M; Taylor G; Ceballos-Diaz C; Kocerha J; Golde T; Das P; Rademakers R; Dickson DW; Kukar T
    Mol Neurodegener; 2012 Oct; 7():53. PubMed ID: 23046583
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activity-dependent FUS dysregulation disrupts synaptic homeostasis.
    Sephton CF; Tang AA; Kulkarni A; West J; Brooks M; Stubblefield JJ; Liu Y; Zhang MQ; Green CB; Huber KM; Huang EJ; Herz J; Yu G
    Proc Natl Acad Sci U S A; 2014 Nov; 111(44):E4769-78. PubMed ID: 25324524
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rapid in vitro quantification of TDP-43 and FUS mislocalisation for screening of gene variants implicated in frontotemporal dementia and amyotrophic lateral sclerosis.
    Oyston LJ; Ubiparipovic S; Fitzpatrick L; Hallupp M; Boccanfuso LM; Kwok JB; Dobson-Stone C
    Sci Rep; 2021 Jul; 11(1):14881. PubMed ID: 34290285
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Defects in synapse structure and function precede motor neuron degeneration in Drosophila models of FUS-related ALS.
    Shahidullah M; Le Marchand SJ; Fei H; Zhang J; Pandey UB; Dalva MB; Pasinelli P; Levitan IB
    J Neurosci; 2013 Dec; 33(50):19590-8. PubMed ID: 24336723
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits.
    Ho WY; Agrawal I; Tyan SH; Sanford E; Chang WT; Lim K; Ong J; Tan BSY; Moe AAK; Yu R; Wong P; Tucker-Kellogg G; Koo E; Chuang KH; Ling SC
    Acta Neuropathol Commun; 2021 Jan; 9(1):9. PubMed ID: 33407930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
    Japtok J; Lojewski X; Naumann M; Klingenstein M; Reinhardt P; Sterneckert J; Putz S; Demestre M; Boeckers TM; Ludolph AC; Liebau S; Storch A; Hermann A
    Neurobiol Dis; 2015 Oct; 82():420-429. PubMed ID: 26253605
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis.
    Tibshirani M; Zhao B; Gentil BJ; Minotti S; Marques C; Keith J; Rogaeva E; Zinman L; Rouaux C; Robertson J; Durham HD
    Hum Mol Genet; 2017 Nov; 26(21):4142-4152. PubMed ID: 28973294
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pathogenesis of FUS-associated ALS and FTD: insights from rodent models.
    Nolan M; Talbot K; Ansorge O
    Acta Neuropathol Commun; 2016 Sep; 4(1):99. PubMed ID: 27600654
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Vascular regression precedes motor neuron loss in the FUS (1-359) ALS mouse model.
    Crivello M; Hogg MC; Jirström E; Halang L; Woods I; Rayner M; Coughlan KS; Lewandowski SA; Prehn JHM
    Dis Model Mech; 2019 Aug; 12(8):. PubMed ID: 31383794
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
    Scekic-Zahirovic J; Sendscheid O; El Oussini H; Jambeau M; Sun Y; Mersmann S; Wagner M; Dieterlé S; Sinniger J; Dirrig-Grosch S; Drenner K; Birling MC; Qiu J; Zhou Y; Li H; Fu XD; Rouaux C; Shelkovnikova T; Witting A; Ludolph AC; Kiefer F; Storkebaum E; Lagier-Tourenne C; Dupuis L
    EMBO J; 2016 May; 35(10):1077-97. PubMed ID: 26951610
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitigation of ALS Pathology by Neuron-Specific Inhibition of Nuclear Factor Kappa B Signaling.
    Dutta K; Thammisetty SS; Boutej H; Bareil C; Julien JP
    J Neurosci; 2020 Jun; 40(26):5137-5154. PubMed ID: 32457070
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FUS causes synaptic hyperexcitability in Drosophila dendritic arborization neurons.
    Machamer JB; Woolums BM; Fuller GG; Lloyd TE
    Brain Res; 2018 Aug; 1693(Pt A):55-66. PubMed ID: 29625118
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trichostatin A Relieves Growth Suppression and Restores Histone Acetylation at Specific Sites in a FUS ALS/FTD Yeast Model.
    Bennett SA; Cobos SN; Mirzakandova M; Fallah M; Son E; Angelakakis G; Rana N; Hugais M; Torrente MP
    Biochemistry; 2021 Dec; 60(48):3671-3675. PubMed ID: 34788013
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.