BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 37974279)

  • 1. Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition.
    Pelaez MC; Desmeules A; Gelon PA; Glasson B; Marcadet L; Rodgers A; Phaneuf D; Pozzi S; Dutchak PA; Julien JP; Sephton CF
    Acta Neuropathol Commun; 2023 Nov; 11(1):182. PubMed ID: 37974279
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.
    López-Erauskin J; Tadokoro T; Baughn MW; Myers B; McAlonis-Downes M; Chillon-Marinas C; Asiaban JN; Artates J; Bui AT; Vetto AP; Lee SK; Le AV; Sun Y; Jambeau M; Boubaker J; Swing D; Qiu J; Hicks GG; Ouyang Z; Fu XD; Tessarollo L; Ling SC; Parone PA; Shaw CE; Marsala M; Lagier-Tourenne C; Cleveland DW; Da Cruz S
    Neuron; 2018 Nov; 100(4):816-830.e7. PubMed ID: 30344044
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits.
    Ho WY; Agrawal I; Tyan SH; Sanford E; Chang WT; Lim K; Ong J; Tan BSY; Moe AAK; Yu R; Wong P; Tucker-Kellogg G; Koo E; Chuang KH; Ling SC
    Acta Neuropathol Commun; 2021 Jan; 9(1):9. PubMed ID: 33407930
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
    Scekic-Zahirovic J; Sendscheid O; El Oussini H; Jambeau M; Sun Y; Mersmann S; Wagner M; Dieterlé S; Sinniger J; Dirrig-Grosch S; Drenner K; Birling MC; Qiu J; Zhou Y; Li H; Fu XD; Rouaux C; Shelkovnikova T; Witting A; Ludolph AC; Kiefer F; Storkebaum E; Lagier-Tourenne C; Dupuis L
    EMBO J; 2016 May; 35(10):1077-97. PubMed ID: 26951610
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The
    Yokoi S; Ito T; Sahashi K; Nakatochi M; Nakamura R; Tohnai G; Fujioka Y; Ishigaki S; Udagawa T; Izumi Y; Morita M; Kano O; Oda M; Sone T; Okano H; Atsuta N; Katsuno M; Okada Y; Sobue G
    J Neurosci; 2022 Nov; 42(47):8881-8896. PubMed ID: 36261283
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion.
    Mitchell JC; McGoldrick P; Vance C; Hortobagyi T; Sreedharan J; Rogelj B; Tudor EL; Smith BN; Klasen C; Miller CC; Cooper JD; Greensmith L; Shaw CE
    Acta Neuropathol; 2013 Feb; 125(2):273-88. PubMed ID: 22961620
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders.
    Matveeva A; Watters O; Rukhadze A; Khemka N; Gentile D; Perez IF; Llorente-Folch I; Farrell C; Lo Cacciato E; Jackson J; Piazzesi A; Wischhof L; Woods I; Halang L; Hogg M; Muñoz AG; Dillon ET; Matallanas D; Arijs I; Lambrechts D; Bano D; Connolly NMC; Prehn JHM
    Amyotroph Lateral Scler Frontotemporal Degener; 2024 Feb; 25(1-2):135-149. PubMed ID: 37779364
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
    Scekic-Zahirovic J; Sanjuan-Ruiz I; Kan V; Megat S; De Rossi P; Dieterlé S; Cassel R; Jamet M; Kessler P; Wiesner D; Tzeplaeff L; Demais V; Sahadevan S; Hembach KM; Muller HP; Picchiarelli G; Mishra N; Antonucci S; Dirrig-Grosch S; Kassubek J; Rasche V; Ludolph A; Boutillier AL; Roselli F; Polymenidou M; Lagier-Tourenne C; Liebscher S; Dupuis L
    Nat Commun; 2021 May; 12(1):3028. PubMed ID: 34021132
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice.
    Devoy A; Kalmar B; Stewart M; Park H; Burke B; Noy SJ; Redhead Y; Humphrey J; Lo K; Jaeger J; Mejia Maza A; Sivakumar P; Bertolin C; Soraru G; Plagnol V; Greensmith L; Acevedo Arozena A; Isaacs AM; Davies B; Fratta P; Fisher EMC
    Brain; 2017 Nov; 140(11):2797-2805. PubMed ID: 29053787
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutant FUS induces chromatin reorganization in the hippocampus and alters memory processes.
    Tzeplaeff L; Seguin J; Le Gras S; Megat S; Cosquer B; Plassard D; Dieterlé S; Paiva I; Picchiarelli G; Decraene C; Alcala-Vida R; Cassel JC; Merienne K; Dupuis L; Boutillier AL
    Prog Neurobiol; 2023 Aug; 227():102483. PubMed ID: 37327984
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.
    Rhine K; Makurath MA; Liu J; Skanchy S; Lopez C; Catalan KF; Ma Y; Fare CM; Shorter J; Ha T; Chemla YR; Myong S
    Mol Cell; 2020 Nov; 80(4):666-681.e8. PubMed ID: 33159856
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TDP-43 pathology and functional deficits in wild-type and ALS/FTD mutant cyclin F mouse models.
    van Hummel A; Sabale M; Przybyla M; van der Hoven J; Chan G; Feiten AF; Chung RS; Ittner LM; Ke YD
    Neuropathol Appl Neurobiol; 2023 Apr; 49(2):e12902. PubMed ID: 36951214
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia.
    Marques C; Held A; Dorfman K; Sung J; Song C; Kavuturu AS; Aguilar C; Russo T; Oakley DH; Albers MW; Hyman BT; Petrucelli L; Lagier-Tourenne C; Wainger BJ
    Acta Neuropathol; 2024 Mar; 147(1):56. PubMed ID: 38478117
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear-import receptors as gatekeepers of pathological phase transitions in ALS/FTD.
    Khalil B; Linsenmeier M; Smith CL; Shorter J; Rossoll W
    Mol Neurodegener; 2024 Jan; 19(1):8. PubMed ID: 38254150
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neuroprotective effects of niclosamide on disease progression via inflammatory pathways modulation in SOD1-G93A and FUS-associated amyotrophic lateral sclerosis models.
    Milani M; Della Valle I; Rossi S; Fabbrizio P; Margotta C; Nardo G; Cozzolino M; D'Ambrosi N; Apolloni S
    Neurotherapeutics; 2024 Apr; 21(3):e00346. PubMed ID: 38493058
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Zebrafish CCNF and FUS Mediate Stress-Specific Motor Responses.
    Aksoy YA; Cole AJ; Deng W; Hesselson D
    Cells; 2024 Feb; 13(5):. PubMed ID: 38474336
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
    Jutzi D; Campagne S; Schmidt R; Reber S; Mechtersheimer J; Gypas F; Schweingruber C; Colombo M; von Schroetter C; Loughlin FE; Devoy A; Hedlund E; Zavolan M; Allain FH; Ruepp MD
    Nat Commun; 2020 Dec; 11(1):6341. PubMed ID: 33311468
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease.
    Kodavati M; Wang H; Guo W; Mitra J; Hegde PM; Provasek V; Rao VHM; Vedula I; Zhang A; Mitra S; Tomkinson AE; Hamilton DJ; Van Den Bosch L; Hegde ML
    Nat Commun; 2024 Mar; 15(1):2156. PubMed ID: 38461154
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43.
    Godoy-Corchuelo JM; Ali Z; Brito Armas JM; Martins-Bach AB; García-Toledo I; Fernández-Beltrán LC; López-Carbonero JI; Bascuñana P; Spring S; Jimenez-Coca I; Muñoz de Bustillo Alfaro RA; Sánchez-Barrena MJ; Nair RR; Nieman BJ; Lerch JP; Miller KL; Ozdinler HP; Fisher EMC; Cunningham TJ; Acevedo-Arozena A; Corrochano S
    Neurobiol Dis; 2024 Apr; 193():106437. PubMed ID: 38367882
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutation of the ALS/FTD-associated RNA-binding protein FUS affects axonal development.
    Tartwijk FWV; Wunderlich LCS; Mela I; Makarchuk S; Jakobs MAH; Qamar S; Franze K; Schierle GSK; George-Hyslop PHS; Lin JQ; Holt CE; Kaminski CF
    J Neurosci; 2024 May; ():. PubMed ID: 38692734
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.