408 related articles for article (PubMed ID: 37974279)
21. Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice.
So E; Mitchell JC; Memmi C; Chennell G; Vizcay-Barrena G; Allison L; Shaw CE; Vance C
Hum Mol Genet; 2018 Feb; 27(3):463-474. PubMed ID: 29194538
[TBL] [Abstract][Full Text] [Related]
22. Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD.
Kumar S; Phaneuf D; Cordeau P; Boutej H; Kriz J; Julien JP
Mol Neurodegener; 2021 Jan; 16(1):1. PubMed ID: 33413517
[TBL] [Abstract][Full Text] [Related]
23. Extensive splicing changes in an ALS/FTD transgenic mouse model overexpressing cytoplasmic fused in sarcoma.
Ito D; Taguchi R; Deguchi M; Ogasawara H; Inoue E
Sci Rep; 2020 Mar; 10(1):4857. PubMed ID: 32184412
[TBL] [Abstract][Full Text] [Related]
24. Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice.
Shelkovnikova TA; Peters OM; Deykin AV; Connor-Robson N; Robinson H; Ustyugov AA; Bachurin SO; Ermolkevich TG; Goldman IL; Sadchikova ER; Kovrazhkina EA; Skvortsova VI; Ling SC; Da Cruz S; Parone PA; Buchman VL; Ninkina NN
J Biol Chem; 2013 Aug; 288(35):25266-25274. PubMed ID: 23867462
[TBL] [Abstract][Full Text] [Related]
25. Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD.
Starr A; Sattler R
Brain Res; 2018 Aug; 1693(Pt A):98-108. PubMed ID: 29453960
[TBL] [Abstract][Full Text] [Related]
26. FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Huang C; Zhou H; Tong J; Chen H; Liu YJ; Wang D; Wei X; Xia XG
PLoS Genet; 2011 Mar; 7(3):e1002011. PubMed ID: 21408206
[TBL] [Abstract][Full Text] [Related]
27. Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis.
Korobeynikov VA; Lyashchenko AK; Blanco-Redondo B; Jafar-Nejad P; Shneider NA
Nat Med; 2022 Jan; 28(1):104-116. PubMed ID: 35075293
[TBL] [Abstract][Full Text] [Related]
28. Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease.
Gelon PA; Dutchak PA; Sephton CF
Front Mol Neurosci; 2022; 15():1000183. PubMed ID: 36263379
[TBL] [Abstract][Full Text] [Related]
29. Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss.
White MA; Lin Z; Kim E; Henstridge CM; Pena Altamira E; Hunt CK; Burchill E; Callaghan I; Loreto A; Brown-Wright H; Mead R; Simmons C; Cash D; Coleman MP; Sreedharan J
Acta Neuropathol Commun; 2019 Oct; 7(1):166. PubMed ID: 31661035
[TBL] [Abstract][Full Text] [Related]
30. Identification of a novel interaction of FUS and syntaphilin may explain synaptic and mitochondrial abnormalities caused by ALS mutations.
Salam S; Tacconelli S; Smith BN; Mitchell JC; Glennon E; Nikolaou N; Houart C; Vance C
Sci Rep; 2021 Jun; 11(1):13613. PubMed ID: 34193962
[TBL] [Abstract][Full Text] [Related]
31. Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 mice.
McCann EP; Fifita JA; Grima N; Galper J; Mehta P; Freckleton SE; Zhang KY; Henden L; Hogan AL; Chan Moi Fat S; Wu SS; Jagaraj CJ; Berning BA; Williams KL; Twine NA; Bauer D; Piguet O; Hodges J; Kwok JBJ; Halliday GM; Kiernan MC; Atkin J; Rowe DB; Nicholson GA; Walker AK; Blair IP; Yang S
J Neurol Neurosurg Psychiatry; 2020 Feb; 91(2):162-171. PubMed ID: 31690696
[TBL] [Abstract][Full Text] [Related]
32. Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.
Scekic-Zahirovic J; Oussini HE; Mersmann S; Drenner K; Wagner M; Sun Y; Allmeroth K; Dieterlé S; Sinniger J; Dirrig-Grosch S; René F; Dormann D; Haass C; Ludolph AC; Lagier-Tourenne C; Storkebaum E; Dupuis L
Acta Neuropathol; 2017 Jun; 133(6):887-906. PubMed ID: 28243725
[TBL] [Abstract][Full Text] [Related]
33. The
Yokoi S; Ito T; Sahashi K; Nakatochi M; Nakamura R; Tohnai G; Fujioka Y; Ishigaki S; Udagawa T; Izumi Y; Morita M; Kano O; Oda M; Sone T; Okano H; Atsuta N; Katsuno M; Okada Y; Sobue G
J Neurosci; 2022 Nov; 42(47):8881-8896. PubMed ID: 36261283
[TBL] [Abstract][Full Text] [Related]
34. A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia.
Vernay A; Therreau L; Blot B; Risson V; Dirrig-Grosch S; Waegaert R; Lequeu T; Sellal F; Schaeffer L; Sadoul R; Loeffler JP; René F
Hum Mol Genet; 2016 Aug; 25(15):3341-3360. PubMed ID: 27329763
[TBL] [Abstract][Full Text] [Related]
35. Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations.
Finelli MJ; Liu KX; Wu Y; Oliver PL; Davies KE
Hum Mol Genet; 2015 Jun; 24(12):3529-44. PubMed ID: 25792726
[TBL] [Abstract][Full Text] [Related]
36. ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.
Stoica R; Paillusson S; Gomez-Suaga P; Mitchell JC; Lau DH; Gray EH; Sancho RM; Vizcay-Barrena G; De Vos KJ; Shaw CE; Hanger DP; Noble W; Miller CC
EMBO Rep; 2016 Sep; 17(9):1326-42. PubMed ID: 27418313
[TBL] [Abstract][Full Text] [Related]
37. Longitudinal transcriptomic analysis of altered pathways in a CHMP2B
Waegaert R; Dirrig-Grosch S; Parisot F; Keime C; Henriques A; Loeffler JP; René F
Neurobiol Dis; 2020 Mar; 136():104710. PubMed ID: 31837425
[TBL] [Abstract][Full Text] [Related]
38. Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations.
Tradewell ML; Yu Z; Tibshirani M; Boulanger MC; Durham HD; Richard S
Hum Mol Genet; 2012 Jan; 21(1):136-49. PubMed ID: 21965298
[TBL] [Abstract][Full Text] [Related]
39. FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins.
Steyaert J; Scheveneels W; Vanneste J; Van Damme P; Robberecht W; Callaerts P; Bogaert E; Van Den Bosch L
Hum Mol Genet; 2018 Dec; 27(23):4103-4116. PubMed ID: 30379317
[TBL] [Abstract][Full Text] [Related]
40. Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis.
Tyzack GE; Luisier R; Taha DM; Neeves J; Modic M; Mitchell JS; Meyer I; Greensmith L; Newcombe J; Ule J; Luscombe NM; Patani R
Brain; 2019 Sep; 142(9):2572-2580. PubMed ID: 31368485
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]