BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 37976356)

  • 1. The SMYD3-MAP3K2 signaling axis promotes tumor aggressiveness and metastasis in prostate cancer.
    Ikram S; Rege A; Negesse MY; Casanova AG; Reynoird N; Green EM
    Sci Adv; 2023 Nov; 9(46):eadi5921. PubMed ID: 37976356
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
    Mazur PK; Reynoird N; Khatri P; Jansen PW; Wilkinson AW; Liu S; Barbash O; Van Aller GS; Huddleston M; Dhanak D; Tummino PJ; Kruger RG; Garcia BA; Butte AJ; Vermeulen M; Sage J; Gozani O
    Nature; 2014 Jun; 510(7504):283-7. PubMed ID: 24847881
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lysine methylation in cancer: SMYD3-MAP3K2 teaches us new lessons in the Ras-ERK pathway.
    Colón-Bolea P; Crespo P
    Bioessays; 2014 Dec; 36(12):1162-9. PubMed ID: 25382779
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase.
    Fu W; Liu N; Qiao Q; Wang M; Min J; Zhu B; Xu RM; Yang N
    J Biol Chem; 2016 Apr; 291(17):9173-80. PubMed ID: 26929412
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3.
    Vieira FQ; Costa-Pinheiro P; Almeida-Rios D; Graça I; Monteiro-Reis S; Simões-Sousa S; Carneiro I; Sousa EJ; Godinho MI; Baltazar F; Henrique R; Jerónimo C
    Oncotarget; 2015 May; 6(15):13644-57. PubMed ID: 25980436
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histone lysine methyltransferase SMYD3 promotes oral squamous cell carcinoma tumorigenesis via H3K4me3-mediated HMGA2 transcription.
    Yang Z; Liu F; Li Z; Liu N; Yao X; Zhou Y; Zhang L; Jiang P; Liu H; Kong L; Lang C; Xu X; Jia J; Nakajima T; Gu W; Zheng L; Zhang Z
    Clin Epigenetics; 2023 May; 15(1):92. PubMed ID: 37237385
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Smyd3-associated regulatory pathways in cancer.
    Giakountis A; Moulos P; Sarris ME; Hatzis P; Talianidis I
    Semin Cancer Biol; 2017 Feb; 42():70-80. PubMed ID: 27554136
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
    Yoshioka Y; Suzuki T; Matsuo Y; Tsurita G; Watanabe T; Dohmae N; Nakamura Y; Hamamoto R
    Cancer Med; 2017 Jul; 6(7):1665-1672. PubMed ID: 28639750
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5.
    Fulford L; Milewski D; Ustiyan V; Ravishankar N; Cai Y; Le T; Masineni S; Kasper S; Aronow B; Kalinichenko VV; Kalin TV
    Sci Signal; 2016 May; 9(427):ra48. PubMed ID: 27165781
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SMYD3: a regulator of epigenetic and signaling pathways in cancer.
    Bernard BJ; Nigam N; Burkitt K; Saloura V
    Clin Epigenetics; 2021 Feb; 13(1):45. PubMed ID: 33637115
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Therapeutical potential of deregulated lysine methyltransferase SMYD3 as a safe target for novel anticancer agents.
    Rajajeyabalachandran G; Kumar S; Murugesan T; Ekambaram S; Padmavathy R; Jegatheesan SK; Mullangi R; Rajagopal S
    Expert Opin Ther Targets; 2017 Feb; 21(2):145-157. PubMed ID: 28019723
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SMYD3 promotes hepatocellular carcinoma progression by methylating S1PR1 promoters.
    Zhang H; Zheng Z; Zhang R; Yan Y; Peng Y; Ye H; Lin L; Xu J; Li W; Huang P
    Cell Death Dis; 2021 Jul; 12(8):731. PubMed ID: 34301921
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting INMT and interrupting its methylation pathway for the treatment of castration resistant prostate cancer.
    Zhong S; Jeong JH; Huang C; Chen X; Dickinson SI; Dhillon J; Yang L; Luo JL
    J Exp Clin Cancer Res; 2021 Sep; 40(1):307. PubMed ID: 34587977
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amplification of SMYD3 promotes tumorigenicity and intrahepatic metastasis of hepatocellular carcinoma via upregulation of CDK2 and MMP2.
    Wang Y; Xie BH; Lin WH; Huang YH; Ni JY; Hu J; Cui W; Zhou J; Shen L; Xu LF; Lian F; Li HP
    Oncogene; 2019 Jun; 38(25):4948-4961. PubMed ID: 30842588
    [TBL] [Abstract][Full Text] [Related]  

  • 15. VHL-HIF-2α axis-induced SMYD3 upregulation drives renal cell carcinoma progression via direct trans-activation of EGFR.
    Liu C; Liu L; Wang K; Li XF; Ge LY; Ma RZ; Fan YD; Li LC; Liu ZF; Qiu M; Hao YC; Shi ZF; Xia CY; Strååt K; Huang Y; Ma LL; Xu D
    Oncogene; 2020 May; 39(21):4286-4298. PubMed ID: 32291411
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SMYD3 promotes epithelial ovarian cancer metastasis by downregulating p53 protein stability and promoting p53 ubiquitination.
    Zhang L; Jin Y; Yang H; Li Y; Wang C; Shi Y; Wang Y
    Carcinogenesis; 2019 Dec; 40(12):1492-1503. PubMed ID: 31002112
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-Based Design of a Novel SMYD3 Inhibitor that Bridges the SAM-and MEKK2-Binding Pockets.
    Van Aller GS; Graves AP; Elkins PA; Bonnette WG; McDevitt PJ; Zappacosta F; Annan RS; Dean TW; Su DS; Carpenter CL; Mohammad HP; Kruger RG
    Structure; 2016 May; 24(5):774-781. PubMed ID: 27066749
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exploration of the Substrate Preference of Lysine Methyltransferase SMYD3 by Molecular Dynamics Simulations.
    Sun J; Shi F; Yang N
    ACS Omega; 2019 Nov; 4(22):19573-19581. PubMed ID: 31788587
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High expression of SMYD3 indicates poor survival outcome and promotes tumour progression through an IGF-1R/AKT/E2F-1 positive feedback loop in bladder cancer.
    Wang G; Huang Y; Yang F; Tian X; Wang K; Liu L; Fan Y; Li X; Li L; Shi B; Hao Y; Xia C; Nie Q; Xin Y; Shi Z; Ma L; Xu D; Liu C
    Aging (Albany NY); 2020 Feb; 12(3):2030-2048. PubMed ID: 32007952
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SMYD3 controls a Wnt-responsive epigenetic switch for ASCL2 activation and cancer stem cell maintenance.
    Wang T; Wu H; Liu S; Lei Z; Qin Z; Wen L; Liu K; Wang X; Guo Y; Liu Q; Liu L; Wang J; Lin L; Mao C; Zhu X; Xiao H; Bian X; Chen D; Xu C; Wang B
    Cancer Lett; 2018 Aug; 430():11-24. PubMed ID: 29746925
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.