136 related articles for article (PubMed ID: 37977812)
1. Significance of Organic Anion Transporter 2 and Organic Cation Transporter 2 in Creatinine Clearance: Mechanistic Evaluation Using Freshly Prepared Human Primary Renal Proximal Tubule Cells.
Mathialagan S; Chung G; Pye K; Rodrigues AD; Varma MVS; Brown C
J Pharmacol Exp Ther; 2024 Jan; 388(1):201-208. PubMed ID: 37977812
[TBL] [Abstract][Full Text] [Related]
2. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression.
Shen H; Liu T; Morse BL; Zhao Y; Zhang Y; Qiu X; Chen C; Lewin AC; Wang XT; Liu G; Christopher LJ; Marathe P; Lai Y
Drug Metab Dispos; 2015 Jul; 43(7):984-93. PubMed ID: 25904762
[TBL] [Abstract][Full Text] [Related]
3. Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat.
Lepist EI; Zhang X; Hao J; Huang J; Kosaka A; Birkus G; Murray BP; Bannister R; Cihlar T; Huang Y; Ray AS
Kidney Int; 2014 Aug; 86(2):350-7. PubMed ID: 24646860
[TBL] [Abstract][Full Text] [Related]
4. Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K.
Xiao G; Rowbottom C; Boiselle C; Gan LS
Pharm Res; 2018 Jun; 35(8):159. PubMed ID: 29915999
[TBL] [Abstract][Full Text] [Related]
5. Role of organic cation transporter OCT2 and multidrug and toxin extrusion proteins MATE1 and MATE2-K for transport and drug interactions of the antiviral lamivudine.
Müller F; König J; Hoier E; Mandery K; Fromm MF
Biochem Pharmacol; 2013 Sep; 86(6):808-15. PubMed ID: 23876341
[TBL] [Abstract][Full Text] [Related]
6. Tucatinib Inhibits Renal Transporters OCT2 and MATE Without Impacting Renal Function in Healthy Subjects.
Topletz-Erickson AR; Lee AJ; Mayor JG; Rustia EL; Abdulrasool LI; Wise AL; Dailey B; DeChenne S; Walker LN; Alley SC; Endres CJ
J Clin Pharmacol; 2021 Apr; 61(4):461-471. PubMed ID: 32989831
[TBL] [Abstract][Full Text] [Related]
7. Expression of organic anion transporter 2 in the human kidney and its potential role in the tubular secretion of guanine-containing antiviral drugs.
Cheng Y; Vapurcuyan A; Shahidullah M; Aleksunes LM; Pelis RM
Drug Metab Dispos; 2012 Mar; 40(3):617-24. PubMed ID: 22190696
[TBL] [Abstract][Full Text] [Related]
8. Renal Excretion of Dabigatran: The Potential Role of Multidrug and Toxin Extrusion (MATE) Proteins.
Shen H; Yao M; Sinz M; Marathe P; Rodrigues AD; Zhu M
Mol Pharm; 2019 Sep; 16(9):4065-4076. PubMed ID: 31335150
[TBL] [Abstract][Full Text] [Related]
9. Importance of OCT2 and MATE1 for the Cimetidine-Metformin Interaction: Insights from Investigations of Polarized Transport in Single- And Double-Transfected MDCK Cells with a Focus on Perpetrator Disposition.
Müller F; Weitz D; Mertsch K; König J; Fromm MF
Mol Pharm; 2018 Aug; 15(8):3425-3433. PubMed ID: 29975542
[TBL] [Abstract][Full Text] [Related]
10. Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein.
Knop J; Misaka S; Singer K; Hoier E; Müller F; Glaeser H; König J; Fromm MF
PLoS One; 2015; 10(10):e0139370. PubMed ID: 26426900
[TBL] [Abstract][Full Text] [Related]
11. The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.
Misaka S; Knop J; Singer K; Hoier E; Keiser M; Müller F; Glaeser H; König J; Fromm MF
Mol Pharm; 2016 Feb; 13(2):512-9. PubMed ID: 26702643
[TBL] [Abstract][Full Text] [Related]
12. Precise comparison of protein localization among OCT, OAT, and MATE in human kidney.
Motohashi H; Nakao Y; Masuda S; Katsura T; Kamba T; Ogawa O; Inui K
J Pharm Sci; 2013 Sep; 102(9):3302-8. PubMed ID: 23630107
[TBL] [Abstract][Full Text] [Related]
13. Contribution of MATE1 to Renal Secretion of the NMDA Receptor Antagonist Memantine.
Müller F; Weitz D; Derdau V; Sandvoss M; Mertsch K; König J; Fromm MF
Mol Pharm; 2017 Sep; 14(9):2991-2998. PubMed ID: 28708400
[TBL] [Abstract][Full Text] [Related]
14. Assessment of vandetanib as an inhibitor of various human renal transporters: inhibition of multidrug and toxin extrusion as a possible mechanism leading to decreased cisplatin and creatinine clearance.
Shen H; Yang Z; Zhao W; Zhang Y; Rodrigues AD
Drug Metab Dispos; 2013 Dec; 41(12):2095-103. PubMed ID: 24026623
[TBL] [Abstract][Full Text] [Related]
15. Genetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes.
Song IS; Shin HJ; Shin JG
Xenobiotica; 2008 Sep; 38(9):1252-62. PubMed ID: 18728938
[TBL] [Abstract][Full Text] [Related]
16. Elucidation of
Miyake T; Mizuno T; Takehara I; Mochizuki T; Kimura M; Matsuki S; Irie S; Watanabe N; Kato Y; Ieiri I; Maeda K; Ando O; Kusuhara H
Drug Metab Dispos; 2019 Nov; 47(11):1270-1280. PubMed ID: 31511257
[TBL] [Abstract][Full Text] [Related]
17. Molecular mechanism of renal tubular secretion of the antimalarial drug chloroquine.
Müller F; König J; Glaeser H; Schmidt I; Zolk O; Fromm MF; Maas R
Antimicrob Agents Chemother; 2011 Jul; 55(7):3091-8. PubMed ID: 21518836
[TBL] [Abstract][Full Text] [Related]
18. Evaluation of Renal Transporter Inhibition Using Creatinine as a Substrate In Vitro to Assess the Clinical Risk of Elevated Serum Creatinine.
Mathialagan S; Rodrigues AD; Feng B
J Pharm Sci; 2017 Sep; 106(9):2535-2541. PubMed ID: 28416419
[TBL] [Abstract][Full Text] [Related]
19. Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.
Nishizawa K; Yoda N; Morokado F; Komori H; Nakanishi T; Tamai I
PLoS One; 2019; 14(4):e0214862. PubMed ID: 30951542
[TBL] [Abstract][Full Text] [Related]
20. Mechanistic in vitro studies confirm that inhibition of the renal apical efflux transporter multidrug and toxin extrusion (MATE) 1, and not altered absorption, underlies the increased metformin exposure observed in clinical interactions with cimetidine, trimethoprim or pyrimethamine.
Elsby R; Chidlaw S; Outteridge S; Pickering S; Radcliffe A; Sullivan R; Jones H; Butler P
Pharmacol Res Perspect; 2017 Oct; 5(5):. PubMed ID: 28971610
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
