BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 37988788)

  • 1. Unveiling local and global conformational changes and allosteric communications in SOD1 systems using molecular dynamics simulation and network analyses.
    Basith S; Manavalan B; Lee G
    Comput Biol Med; 2024 Jan; 168():107688. PubMed ID: 37988788
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amyotrophic lateral sclerosis disease-related mutations disrupt the dimerization of superoxide dismutase 1 - A comparative molecular dynamics simulation study.
    Basith S; Manavalan B; Lee G
    Comput Biol Med; 2022 Dec; 151(Pt B):106319. PubMed ID: 36446187
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular dynamics of far positioned surface mutations of Cu/Zn SOD1 promotes altered structural stability and metal-binding site: Structural clues to the pathogenesis of amyotrophic lateral sclerosis.
    Tompa DR; Muthusamy S; Srikanth S; Kadhirvel S
    J Mol Graph Model; 2020 Nov; 100():107678. PubMed ID: 32768728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS.
    Vassall KA; Stubbs HR; Primmer HA; Tong MS; Sullivan SM; Sobering R; Srinivasan S; Briere LA; Dunn SD; Colón W; Meiering EM
    Proc Natl Acad Sci U S A; 2011 Feb; 108(6):2210-5. PubMed ID: 21257910
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural instability and Cu-dependent pro-oxidant activity acquired by the apo form of mutant SOD1 associated with amyotrophic lateral sclerosis.
    Kitamura F; Fujimaki N; Okita W; Hiramatsu H; Takeuchi H
    Biochemistry; 2011 May; 50(20):4242-50. PubMed ID: 21506602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SOD1 exhibits allosteric frustration to facilitate metal binding affinity.
    Das A; Plotkin SS
    Proc Natl Acad Sci U S A; 2013 Mar; 110(10):3871-6. PubMed ID: 23431152
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Immature ALS-associated mutant superoxide dismutases form variable aggregate structures through distinct oligomerization processes.
    Deol HK; Broom HR; Siebeneichler B; Lee B; Leonenko Z; Meiering EM
    Biophys Chem; 2022 Sep; 288():106844. PubMed ID: 35872467
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Folding of Cu, Zn superoxide dismutase and familial amyotrophic lateral sclerosis.
    Khare SD; Ding F; Dokholyan NV
    J Mol Biol; 2003 Nov; 334(3):515-25. PubMed ID: 14623191
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformational dynamics of superoxide dismutase (SOD1) in osmolytes: a molecular dynamics simulation study.
    Jahan I; Nayeem SM
    RSC Adv; 2020 Jul; 10(46):27598-27614. PubMed ID: 35516947
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular dynamics of a far positioned SOD1 mutant V14M reveals pathogenic misfolding behavior.
    Tompa DR; Kadhirvel S
    J Biomol Struct Dyn; 2018 Nov; 36(15):4085-4098. PubMed ID: 29157189
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conformational Disorder of the Most Immature Cu, Zn-Superoxide Dismutase Leading to Amyotrophic Lateral Sclerosis.
    Furukawa Y; Anzai I; Akiyama S; Imai M; Cruz FJ; Saio T; Nagasawa K; Nomura T; Ishimori K
    J Biol Chem; 2016 Feb; 291(8):4144-55. PubMed ID: 26694608
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unveiling the unfolding pathway of FALS associated G37R SOD1 mutant: a computational study.
    Milardi D; Pappalardo M; Grasso DM; La Rosa C
    Mol Biosyst; 2010 Jun; 6(6):1032-9. PubMed ID: 20485746
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation.
    Chattopadhyay M; Nwadibia E; Strong CD; Gralla EB; Valentine JS; Whitelegge JP
    J Biol Chem; 2015 Dec; 290(51):30624-36. PubMed ID: 26511321
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alterations in local stability and dynamics of A4V SOD1 in the presence of trifluoroethanol.
    Kumar V; Prakash A; Lynn AM
    Biopolymers; 2018 Mar; 109(3):e23102. PubMed ID: 29369331
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis.
    Rotunno MS; Auclair JR; Maniatis S; Shaffer SA; Agar J; Bosco DA
    J Biol Chem; 2014 Oct; 289(41):28527-38. PubMed ID: 25164820
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Superoxide Dismutase 1 Folding Stability as a Target for Molecular Tweezers in SOD1-Related Amyotrophic Lateral Sclerosis.
    Samanta N; Ruiz-Blanco YB; Fetahaj Z; Gnutt D; Lantz C; Loo JA; Sanchez-Garcia E; Ebbinghaus S
    Chembiochem; 2022 Nov; 23(21):e202200396. PubMed ID: 36083789
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Global structural motions from the strain of a single hydrogen bond.
    Danielsson J; Awad W; Saraboji K; Kurnik M; Lang L; Leinartaite L; Marklund SL; Logan DT; Oliveberg M
    Proc Natl Acad Sci U S A; 2013 Mar; 110(10):3829-34. PubMed ID: 23431167
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V.
    Schmidlin T; Kennedy BK; Daggett V
    Biophys J; 2009 Sep; 97(6):1709-18. PubMed ID: 19751676
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanical probes of SOD1 predict systematic trends in metal and dimer affinity of ALS-associated mutants.
    Das A; Plotkin SS
    J Mol Biol; 2013 Mar; 425(5):850-74. PubMed ID: 23291526
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Computational investigation of the human SOD1 mutant, Cys146Arg, that directs familial amyotrophic lateral sclerosis.
    Srinivasan E; Rajasekaran R
    Mol Biosyst; 2017 Jul; 13(8):1495-1503. PubMed ID: 28621357
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.