BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 38002337)

  • 1.
    Ütkür K; Schmidt S; Mayer K; Klassen R; Brinkmann U; Schaffrath R
    Biomolecules; 2023 Nov; 13(11):. PubMed ID: 38002337
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The asymmetric function of Dph1-Dph2 heterodimer in diphthamide biosynthesis.
    Dong M; Dando EE; Kotliar I; Su X; Dzikovski B; Freed JH; Lin H
    J Biol Inorg Chem; 2019 Sep; 24(6):777-782. PubMed ID: 31463593
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional Integrity of Radical SAM Enzyme Dph1•Dph2 Requires Non-Canonical Cofactor Motifs with Tandem Cysteines.
    Ütkür K; Mayer K; Liu S; Brinkmann U; Schaffrath R
    Biomolecules; 2024 Apr; 14(4):. PubMed ID: 38672486
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dph3 is an electron donor for Dph1-Dph2 in the first step of eukaryotic diphthamide biosynthesis.
    Dong M; Su X; Dzikovski B; Dando EE; Zhu X; Du J; Freed JH; Lin H
    J Am Chem Soc; 2014 Feb; 136(5):1754-7. PubMed ID: 24422557
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dph3 Enables Aerobic Diphthamide Biosynthesis by Donating One Iron Atom to Transform a [3Fe-4S] to a [4Fe-4S] Cluster in Dph1-Dph2.
    Zhang Y; Su D; Dzikovski B; Majer SH; Coleman R; Chandrasekaran S; Fenwick MK; Crane BR; Lancaster KM; Freed JH; Lin H
    J Am Chem Soc; 2021 Jun; 143(25):9314-9319. PubMed ID: 34154323
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.
    Liu S; Milne GT; Kuremsky JG; Fink GR; Leppla SH
    Mol Cell Biol; 2004 Nov; 24(21):9487-97. PubMed ID: 15485916
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DPH1 and DPH2 variants that confer susceptibility to diphthamide deficiency syndrome in human cells and yeast models.
    Ütkür K; Mayer K; Khan M; Manivannan T; Schaffrath R; Brinkmann U
    Dis Model Mech; 2023 Sep; 16(9):. PubMed ID: 37675463
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis.
    Dong M; Horitani M; Dzikovski B; Freed JH; Ealick SE; Hoffman BM; Lin H
    J Am Chem Soc; 2017 Apr; 139(16):5680-5683. PubMed ID: 28383907
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme.
    Zhang Y; Zhu X; Torelli AT; Lee M; Dzikovski B; Koralewski RM; Wang E; Freed J; Krebs C; Ealick SE; Lin H
    Nature; 2010 Jun; 465(7300):891-6. PubMed ID: 20559380
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methods for Studying the Radical SAM Enzymes in Diphthamide Biosynthesis.
    Dong M; Zhang Y; Lin H
    Methods Enzymol; 2018; 606():421-438. PubMed ID: 30097101
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insights into diphthamide, key diphtheria toxin effector.
    Abdel-Fattah W; Scheidt V; Uthman S; Stark MJ; Schaffrath R
    Toxins (Basel); 2013 May; 5(5):958-68. PubMed ID: 23645155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The diphthamide modification pathway from Saccharomyces cerevisiae--revisited.
    Schaffrath R; Abdel-Fattah W; Klassen R; Stark MJ
    Mol Microbiol; 2014 Dec; 94(6):1213-26. PubMed ID: 25352115
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast.
    Hawer H; Ütkür K; Arend M; Mayer K; Adrian L; Brinkmann U; Schaffrath R
    PLoS One; 2018; 13(10):e0205870. PubMed ID: 30335802
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Noncanonical Radical SAM Enzyme Chemistry Learned from Diphthamide Biosynthesis.
    Dong M; Zhang Y; Lin H
    Biochemistry; 2018 Jun; 57(25):3454-3459. PubMed ID: 29708734
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Diphthamide-deficiency syndrome: a novel human developmental disorder and ribosomopathy.
    Hawer H; Mendelsohn BA; Mayer K; Kung A; Malhotra A; Tuupanen S; Schleit J; Brinkmann U; Schaffrath R
    Eur J Hum Genet; 2020 Nov; 28(11):1497-1508. PubMed ID: 32576952
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanistic understanding of Pyrococcus horikoshii Dph2, a [4Fe-4S] enzyme required for diphthamide biosynthesis.
    Zhu X; Dzikovski B; Su X; Torelli AT; Zhang Y; Ealick SE; Freed JH; Lin H
    Mol Biosyst; 2011 Jan; 7(1):74-81. PubMed ID: 20931132
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Crystal Structure of Dph2 in Complex with Elongation Factor 2 Reveals the Structural Basis for the First Step of Diphthamide Biosynthesis.
    Fenwick MK; Dong M; Lin H; Ealick SE
    Biochemistry; 2019 Oct; 58(43):4343-4351. PubMed ID: 31566354
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development.
    Webb TR; Cross SH; McKie L; Edgar R; Vizor L; Harrison J; Peters J; Jackson IJ
    J Cell Sci; 2008 Oct; 121(Pt 19):3140-5. PubMed ID: 18765564
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of diphthamide pre-activates NF-κB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor.
    Stahl S; da Silva Mateus Seidl AR; Ducret A; Kux van Geijtenbeek S; Michel S; Racek T; Birzele F; Haas AK; Rueger R; Gerg M; Niederfellner G; Pastan I; Brinkmann U
    Proc Natl Acad Sci U S A; 2015 Aug; 112(34):10732-7. PubMed ID: 26261303
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The amidation step of diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network.
    Uthman S; Bär C; Scheidt V; Liu S; ten Have S; Giorgini F; Stark MJ; Schaffrath R
    PLoS Genet; 2013; 9(2):e1003334. PubMed ID: 23468660
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.