BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 38006927)

  • 1. The variability in CYP3A4 activity determines the metabolic kinetic characteristics of ketamine.
    Li M; Li Q; Lin D; Zheng X; Jin L; Cai J; Hu G; Qian J
    Toxicology; 2023 Dec; 500():153682. PubMed ID: 38006927
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of drug-drug interactions and CYP3A4 variants on alectinib metabolism.
    Liu YN; Chen J; Wang J; Li Q; Hu GX; Cai JP; Lin G; Xu RA
    Arch Toxicol; 2023 Aug; 97(8):2133-2142. PubMed ID: 37209178
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effect of CYP3A4 genetic polymorphism and drug interaction on the metabolism of istradefylline.
    Hu X; Ni J; Gao N; Ye Z; Hu G; Cai J; Qian J
    Chem Biol Interact; 2022 Oct; 366():110123. PubMed ID: 36007633
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes.
    Murayama N; Imai N; Nakane T; Shimizu M; Yamazaki H
    Biochem Pharmacol; 2007 Jun; 73(12):2020-6. PubMed ID: 17433262
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gene Polymorphisms and Drug-Drug Interactions Determine the Metabolic Profile of Blonanserin.
    Ye F; Li X; Ni J; Xu X; Luo J; Zhong Y; Wang Y; Wang S; Zhang Y; Hu G; Qian J
    J Pharmacol Exp Ther; 2024 Jan; 388(1):190-200. PubMed ID: 37863485
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The impacts of CYP3A4 genetic polymorphism and drug interactions on the metabolism of lurasidone.
    Li Q; Wang J; Wang ZL; Shen Y; Zhou Q; Liu YN; Hu GX; Cai JP; Xu RA
    Biomed Pharmacother; 2023 Dec; 168():115833. PubMed ID: 37935069
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro ketamine CYP3A-mediated metabolism study using mammalian liver S9 fractions, cDNA expressed enzymes and liquid chromatography tandem mass spectrometry.
    Santamaria R; Pailleux F; Beaudry F
    Biomed Chromatogr; 2014 Dec; 28(12):1660-9. PubMed ID: 24729431
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes.
    Hijazi Y; Boulieu R
    Drug Metab Dispos; 2002 Jul; 30(7):853-8. PubMed ID: 12065445
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of Ethanol on the Metabolic Characteristics of HIV-1 Integrase Inhibitor Elvitegravir and Elvitegravir/Cobicistat with CYP3A: An Analysis Using a Newly Developed LC-MS/MS Method.
    Midde NM; Rahman MA; Rathi C; Li J; Meibohm B; Li W; Kumar S
    PLoS One; 2016; 11(2):e0149225. PubMed ID: 26872388
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans.
    Mössner LD; Schmitz A; Theurillat R; Thormann W; Mevissen M
    Am J Vet Res; 2011 Nov; 72(11):1505-13. PubMed ID: 22023129
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The effect of shikonin on the metabolism of lapatinib in vitro, and in vivo.
    Hu Y; Xie S; Xia H; Chen J; Yang Y; Zhan R
    Toxicol Appl Pharmacol; 2024 Jan; 482():116797. PubMed ID: 38160892
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Microsomal cytochrome p450-mediated metabolism of protopanaxatriol ginsenosides: metabolite profile, reaction phenotyping, and structure-metabolism relationship.
    Hao H; Lai L; Zheng C; Wang Q; Yu G; Zhou X; Wu L; Gong P; Wang G
    Drug Metab Dispos; 2010 Oct; 38(10):1731-9. PubMed ID: 20639434
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of CYP2B6 in n-demethylation of ketamine in human liver microsomes.
    Yanagihara Y; Kariya S; Ohtani M; Uchino K; Aoyama T; Yamamura Y; Iga T
    Drug Metab Dispos; 2001 Jun; 29(6):887-90. PubMed ID: 11353758
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of flavonoids and CYP3A4 variants on midostaurin metabolism.
    Xu RA; Li QQ; Gao NY; Wang J; Li XY; Ye F; Ni JH; Hu GX; Qian JC
    Food Chem Toxicol; 2023 Apr; 174():113669. PubMed ID: 36805545
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Physiologically Based Pharmacokinetic Model of Voriconazole Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Predictions of Drug-Drug Interactions.
    Li X; Frechen S; Moj D; Lehr T; Taubert M; Hsin CH; Mikus G; Neuvonen PJ; Olkkola KT; Saari TI; Fuhr U
    Clin Pharmacokinet; 2020 Jun; 59(6):781-808. PubMed ID: 31853755
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro hepatic metabolism explains higher clearance of voriconazole in children versus adults: role of CYP2C19 and flavin-containing monooxygenase 3.
    Yanni SB; Annaert PP; Augustijns P; Ibrahim JG; Benjamin DK; Thakker DR
    Drug Metab Dispos; 2010 Jan; 38(1):25-31. PubMed ID: 19841059
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of the inhibitory effect of azoles on pharmacokinetics of lenvatinib in rats both in vivo and in vitro by UPLC-MS/MS.
    Xia M; Song X; Lu Z; Wang Y; Zhou Q; Geng P; Wang S; Zhou Y; Wu Q; Han A
    Thorac Cancer; 2023 Nov; 14(33):3331-3341. PubMed ID: 37771131
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE) a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs.
    Brandes LJ; Queen GM; LaBella FS
    Cancer Chemother Pharmacol; 2000; 45(4):298-304. PubMed ID: 10755318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The CYP2B6*6 allele significantly alters the N-demethylation of ketamine enantiomers in vitro.
    Li Y; Coller JK; Hutchinson MR; Klein K; Zanger UM; Stanley NJ; Abell AD; Somogyi AA
    Drug Metab Dispos; 2013 Jun; 41(6):1264-72. PubMed ID: 23550066
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In-vitro metabolism of glycyrrhetinic acid by human and rat liver microsomes and its interactions with six CYP substrates.
    Zhao K; Ding M; Cao H; Cao ZX
    J Pharm Pharmacol; 2012 Oct; 64(10):1445-51. PubMed ID: 22943175
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.