BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 38012390)

  • 1. H3K36 methyltransferase NSD1 protects against osteoarthritis through regulating chondrocyte differentiation and cartilage homeostasis.
    Shao R; Suo J; Zhang Z; Kong M; Ma Y; Wen Y; Liu M; Zhuang L; Ge K; Bi Q; Zhang C; Zou W
    Cell Death Differ; 2024 Jan; 31(1):106-118. PubMed ID: 38012390
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis.
    Yang S; Ryu JH; Oh H; Jeon J; Kwak JS; Kim JH; Kim HA; Chun CH; Chun JS
    Ann Rheum Dis; 2015 Mar; 74(3):595-602. PubMed ID: 24347567
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis.
    Won Y; Shin Y; Chun CH; Cho Y; Ha CW; Kim JH; Chun JS
    Ann Rheum Dis; 2016 Nov; 75(11):2045-2052. PubMed ID: 26903440
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular regulation of articular chondrocyte function and its significance in osteoarthritis.
    Schroeppel JP; Crist JD; Anderson HC; Wang J
    Histol Histopathol; 2011 Mar; 26(3):377-94. PubMed ID: 21210351
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chaperonin 60 regulation of SOX9 ubiquitination mitigates the development of knee osteoarthritis.
    Ko JY; Sun YC; Li WC; Wang FS
    J Mol Med (Berl); 2016 Jul; 94(7):755-69. PubMed ID: 27118120
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.
    Wang Q; Tan QY; Xu W; Qi HB; Chen D; Zhou S; Ni ZH; Kuang L; Guo JY; Huang JL; Wang XX; Wang ZQ; Su N; Chen L; Chen B; Jiang WL; Gao Y; Chen HG; Du XL; Xie YL; Chen L
    Osteoarthritis Cartilage; 2017 Nov; 25(11):1868-1879. PubMed ID: 28716756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis.
    Wang C; Shen J; Ying J; Xiao D; O'Keefe RJ
    Proc Natl Acad Sci U S A; 2020 Dec; 117(48):30488-30497. PubMed ID: 33199631
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kdm6b regulates cartilage development and homeostasis through anabolic metabolism.
    Dai J; Yu D; Wang Y; Chen Y; Sun H; Zhang X; Zhu S; Pan Z; Heng BC; Zhang S; Ouyang H
    Ann Rheum Dis; 2017 Jul; 76(7):1295-1303. PubMed ID: 28314754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transcription factor Nfat1 deficiency causes osteoarthritis through dysfunction of adult articular chondrocytes.
    Wang J; Gardner BM; Lu Q; Rodova M; Woodbury BG; Yost JG; Roby KF; Pinson DM; Tawfik O; Anderson HC
    J Pathol; 2009 Oct; 219(2):163-72. PubMed ID: 19526482
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chemically modified curcumin (CMC2.24) alleviates osteoarthritis progression by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis via the NF-κB/HIF-2α axis.
    Zhou Y; Ming J; Deng M; Li Y; Li B; Li J; Ma Y; Chen Z; Wang G; Liu S
    J Mol Med (Berl); 2020 Oct; 98(10):1479-1491. PubMed ID: 32860098
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The H3.3 G34W oncohistone mutation increases K36 methylation by the protein lysine methyltransferase NSD1.
    Bröhm A; Schoch T; Grünberger D; Khella MS; Schuhmacher MK; Weirich S; Jeltsch A
    Biochimie; 2022 Jul; 198():86-91. PubMed ID: 35341929
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Low-density lipoprotein receptor-related protein 5 governs Wnt-mediated osteoarthritic cartilage destruction.
    Shin Y; Huh YH; Kim K; Kim S; Park KH; Koh JT; Chun JS; Ryu JH
    Arthritis Res Ther; 2014 Jan; 16(1):R37. PubMed ID: 24479426
    [TBL] [Abstract][Full Text] [Related]  

  • 13. EGFR signaling is critical for maintaining the superficial layer of articular cartilage and preventing osteoarthritis initiation.
    Jia H; Ma X; Tong W; Doyran B; Sun Z; Wang L; Zhang X; Zhou Y; Badar F; Chandra A; Lu XL; Xia Y; Han L; Enomoto-Iwamoto M; Qin L
    Proc Natl Acad Sci U S A; 2016 Dec; 113(50):14360-14365. PubMed ID: 27911782
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reciprocal activation of hypoxia-inducible factor (HIF)-2α and the zinc-ZIP8-MTF1 axis amplifies catabolic signaling in osteoarthritis.
    Lee M; Won Y; Shin Y; Kim JH; Chun JS
    Osteoarthritis Cartilage; 2016 Jan; 24(1):134-45. PubMed ID: 26241779
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.
    Ijiri K; Zerbini LF; Peng H; Otu HH; Tsuchimochi K; Otero M; Dragomir C; Walsh N; Bierbaum BE; Mattingly D; van Flandern G; Komiya S; Aigner T; Libermann TA; Goldring MB
    Arthritis Rheum; 2008 Jul; 58(7):2075-87. PubMed ID: 18576389
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inducible chondrocyte-specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage.
    Blaney Davidson EN; Vitters EL; Bennink MB; van Lent PL; van Caam AP; Blom AB; van den Berg WB; van de Loo FA; van der Kraan PM
    Ann Rheum Dis; 2015 Jun; 74(6):1257-64. PubMed ID: 24448347
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice.
    Zhu M; Tang D; Wu Q; Hao S; Chen M; Xie C; Rosier RN; O'Keefe RJ; Zuscik M; Chen D
    J Bone Miner Res; 2009 Jan; 24(1):12-21. PubMed ID: 18767925
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone.
    Xuan F; Yano F; Mori D; Chijimatsu R; Maenohara Y; Nakamoto H; Mori Y; Makii Y; Oichi T; Taketo MM; Hojo H; Ohba S; Chung UI; Tanaka S; Saito T
    Arthritis Res Ther; 2019 Nov; 21(1):247. PubMed ID: 31771658
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Macrophage-derived ectosomal miR-350-3p promotes osteoarthritis progression through downregulating chondrocyte H3K36 methyltransferase NSD1.
    Lin R; Yin J; Huang J; Zou L; Liu L; Tang W; Zhang H; Yang L; Zhang Y; Li G; Wang G; Cai D; Zhang H; Liu Y; Shao Y
    Cell Death Discov; 2024 May; 10(1):223. PubMed ID: 38719811
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function.
    Zhuang L; Jang Y; Park YK; Lee JE; Jain S; Froimchuk E; Broun A; Liu C; Gavrilova O; Ge K
    Nat Commun; 2018 May; 9(1):1796. PubMed ID: 29728617
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.