167 related articles for article (PubMed ID: 38015832)
21. Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities.
Podtelezhnikov AA; Monroe JJ; Aslamkhan AG; Pearson K; Qin C; Tamburino AM; Loboda AP; Glaab WE; Sistare FD; Tanis KQ
Toxicol Sci; 2020 May; 175(1):98-112. PubMed ID: 32119089
[TBL] [Abstract][Full Text] [Related]
22. Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury.
Tolosa L; Jiménez N; Pérez G; Castell JV; Gómez-Lechón MJ; Donato MT
Arch Toxicol; 2018 Jan; 92(1):383-399. PubMed ID: 28762043
[TBL] [Abstract][Full Text] [Related]
23. High content analysis assay for prediction of human hepatotoxicity in HepaRG and HepG2 cells.
Saito J; Okamura A; Takeuchi K; Hanioka K; Okada A; Ohata T
Toxicol In Vitro; 2016 Jun; 33():63-70. PubMed ID: 26921665
[TBL] [Abstract][Full Text] [Related]
24. Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems.
Rodrigues RM; Heymans A; De Boe V; Sachinidis A; Chaudhari U; Govaere O; Roskams T; Vanhaecke T; Rogiers V; De Kock J
Toxicol Lett; 2016 Jan; 240(1):50-9. PubMed ID: 26497421
[TBL] [Abstract][Full Text] [Related]
25. Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline.
Kang W; Podtelezhnikov AA; Tanis KQ; Pacchione S; Su M; Bleicher KB; Wang Z; Laws GM; Griffiths TG; Kuhls MC; Chen Q; Knemeyer I; Marsh DJ; Mitra K; Lebron J; Sistare FD
Toxicol Sci; 2020 Sep; 177(1):121-139. PubMed ID: 32559289
[TBL] [Abstract][Full Text] [Related]
26. Toxicogenomics of drug induced liver injury - from mechanistic understanding to early prediction.
Lauschke VM
Drug Metab Rev; 2021 May; 53(2):245-252. PubMed ID: 33683927
[TBL] [Abstract][Full Text] [Related]
27. A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.
Sison-Young RL; Lauschke VM; Johann E; Alexandre E; Antherieu S; Aerts H; Gerets HHJ; Labbe G; Hoët D; Dorau M; Schofield CA; Lovatt CA; Holder JC; Stahl SH; Richert L; Kitteringham NR; Jones RP; Elmasry M; Weaver RJ; Hewitt PG; Ingelman-Sundberg M; Goldring CE; Park BK
Arch Toxicol; 2017 Mar; 91(3):1385-1400. PubMed ID: 27344343
[TBL] [Abstract][Full Text] [Related]
28. Exploring the Immune Landscape of Cirrhosis through Weighted Gene Co-expression Network Analysis.
Zhuoma B; Yang C; Wang W; Ranhen Y
Cell Mol Biol (Noisy-le-grand); 2023 Jun; 69(6):168-174. PubMed ID: 37605574
[TBL] [Abstract][Full Text] [Related]
29. Comparing in vitro human liver models to in vivo human liver using RNA-Seq.
Gupta R; Schrooders Y; Hauser D; van Herwijnen M; Albrecht W; Ter Braak B; Brecklinghaus T; Castell JV; Elenschneider L; Escher S; Guye P; Hengstler JG; Ghallab A; Hansen T; Leist M; Maclennan R; Moritz W; Tolosa L; Tricot T; Verfaillie C; Walker P; van de Water B; Kleinjans J; Caiment F
Arch Toxicol; 2021 Feb; 95(2):573-589. PubMed ID: 33106934
[TBL] [Abstract][Full Text] [Related]
30. Predose and Postdose Blood Gene Expression Profiles Identify the Individuals Susceptible to Acetaminophen-Induced Liver Injury in Rats.
Lu X; Hu B; Zheng J; Ji C; Fan X; Gao Y
PLoS One; 2015; 10(10):e0141750. PubMed ID: 26512990
[TBL] [Abstract][Full Text] [Related]
31. Development of an in vitro cholestatic drug-induced liver injury evaluation system using HepG2-hNTCP-C4 cells in sandwich configuration.
Sakai Y; Okumura H; Iwao T; Watashi K; Ito K; Matsunaga T
Toxicol In Vitro; 2019 Dec; 61():104619. PubMed ID: 31394163
[TBL] [Abstract][Full Text] [Related]
32. 3,3',5-triiodo-l-thyronine inhibits drug-induced liver injury through activation of PPARα as revealed by network pharmacology and biological experimental verification.
Liu K; Chen X; Ren Y; Liu C; Zhang J; Wang Z; Li Y; Zhang Y
Toxicol Appl Pharmacol; 2022 Aug; 448():116098. PubMed ID: 35662663
[TBL] [Abstract][Full Text] [Related]
33. Cell-based assay using glutathione-depleted HepaRG and HepG2 human liver cells for predicting drug-induced liver injury.
Xu J; Oda S; Yokoi T
Toxicol In Vitro; 2018 Apr; 48():286-301. PubMed ID: 29407385
[TBL] [Abstract][Full Text] [Related]
34. Assessment of Drug-Induced Liver Injury through Cell Morphology and Gene Expression Analysis.
Lejal V; Cerisier N; Rouquié D; Taboureau O
Chem Res Toxicol; 2023 Sep; 36(9):1456-1470. PubMed ID: 37652439
[TBL] [Abstract][Full Text] [Related]
35. Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment.
Kunnen SJ; Arnesdotter E; Willenbockel CT; Vinken M; van de Water B
ALTEX; 2024; 41(2):213-232. PubMed ID: 38376873
[TBL] [Abstract][Full Text] [Related]
36. Validation of gene expression profiles from cholestatic hepatotoxicants in vitro against human in vivo cholestasis.
Van den Hof WFPM; Coonen MLJ; van Herwijnen M; Brauers K; Jennen D; Olde Damink SWM; Schaap FG; Kleinjans JCS
Toxicol In Vitro; 2017 Oct; 44():322-329. PubMed ID: 28778767
[TBL] [Abstract][Full Text] [Related]
37. Evaluation of the use of imaging parameters for the detection of compound-induced hepatotoxicity in 384-well cultures of HepG2 cells and cryopreserved primary human hepatocytes.
Garside H; Marcoe KF; Chesnut-Speelman J; Foster AJ; Muthas D; Kenna JG; Warrior U; Bowes J; Baumgartner J
Toxicol In Vitro; 2014 Mar; 28(2):171-81. PubMed ID: 24189122
[TBL] [Abstract][Full Text] [Related]
38. Editor's Highlight: Candidate Risk Factors and Mechanisms for Tolvaptan-Induced Liver Injury Are Identified Using a Collaborative Cross Approach.
Mosedale M; Kim Y; Brock WJ; Roth SE; Wiltshire T; Eaddy JS; Keele GR; Corty RW; Xie Y; Valdar W; Watkins PB
Toxicol Sci; 2017 Apr; 156(2):438-454. PubMed ID: 28115652
[TBL] [Abstract][Full Text] [Related]
39. A novel cell-based assay for the evaluation of immune- and inflammatory-related gene expression as biomarkers for the risk assessment of drug-induced liver injury.
Oda S; Matsuo K; Nakajima A; Yokoi T
Toxicol Lett; 2016 Jan; 241():60-70. PubMed ID: 26546780
[TBL] [Abstract][Full Text] [Related]
40. A high content screening assay to predict human drug-induced liver injury during drug discovery.
Persson M; Løye AF; Mow T; Hornberg JJ
J Pharmacol Toxicol Methods; 2013; 68(3):302-13. PubMed ID: 23933113
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
