213 related articles for article (PubMed ID: 38021158)
1. Lapatinib dysregulates HER2 signaling and impairs the viability of human uveal melanoma cells.
Shu W; Wang JZ; Zhu X; Wang K; Cherepanoff S; Conway RM; Madigan MC; Lim LA; Zhu H; Zhu L; Murray M; Zhou F
J Cancer; 2023; 14(18):3477-3495. PubMed ID: 38021158
[TBL] [Abstract][Full Text] [Related]
2. The multi-kinase inhibitor afatinib serves as a novel candidate for the treatment of human uveal melanoma.
Shu W; Zhu X; Wang K; Cherepanoff S; Conway RM; Madigan MC; Zhu H; Zhu L; Murray M; Zhou F
Cell Oncol (Dordr); 2022 Aug; 45(4):601-619. PubMed ID: 35781872
[TBL] [Abstract][Full Text] [Related]
3. Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway.
Yan F; Liao R; Silva M; Li S; Jiang Y; Peng T; Lazarovici P; Zheng W
J Cell Mol Med; 2020 Jun; 24(11):6208-6219. PubMed ID: 32347651
[TBL] [Abstract][Full Text] [Related]
4. Dual mTORC1/2 and HER2 blockade results in antitumor activity in preclinical models of breast cancer resistant to anti-HER2 therapy.
García-García C; Ibrahim YH; Serra V; Calvo MT; Guzmán M; Grueso J; Aura C; Pérez J; Jessen K; Liu Y; Rommel C; Tabernero J; Baselga J; Scaltriti M
Clin Cancer Res; 2012 May; 18(9):2603-12. PubMed ID: 22407832
[TBL] [Abstract][Full Text] [Related]
5. Elevated ZNF704 expression is associated with poor prognosis of uveal melanoma and promotes cancer cell growth by regulating AKT/mTOR signaling.
Luo J; Li H; Xiu J; Zeng J; Feng Z; Zhao H; Li Y; Wei W
Biomark Res; 2023 Apr; 11(1):38. PubMed ID: 37038184
[TBL] [Abstract][Full Text] [Related]
6. Natural withanolide withaferin A induces apoptosis in uveal melanoma cells by suppression of Akt and c-MET activation.
Samadi AK; Cohen SM; Mukerji R; Chaguturu V; Zhang X; Timmermann BN; Cohen MS; Person EA
Tumour Biol; 2012 Aug; 33(4):1179-89. PubMed ID: 22477711
[TBL] [Abstract][Full Text] [Related]
7. Lapatinib alters the malignant phenotype of osteosarcoma cells via downregulation of the activity of the HER2-PI3K/AKT-FASN axis in vitro.
Long XH; Zhang GM; Peng AF; Luo QF; Zhang L; Wen HC; Zhou RP; Gao S; Zhou Y; Liu ZL
Oncol Rep; 2014 Jan; 31(1):328-34. PubMed ID: 24172910
[TBL] [Abstract][Full Text] [Related]
8. Elucidating the role of the FoxO3a transcription factor in the IGF-1-induced migration and invasion of uveal melanoma cancer cells.
Yan F; Liao R; Farhan M; Wang T; Chen J; Wang Z; Little PJ; Zheng W
Biomed Pharmacother; 2016 Dec; 84():1538-1550. PubMed ID: 27881235
[TBL] [Abstract][Full Text] [Related]
9. Ergolide mediates anti-cancer effects on metastatic uveal melanoma cells and modulates their cellular and extracellular vesicle proteomes.
Sundaramurthi H; Tonelotto V; Wynne K; O'Connell F; O'Reilly E; Costa-Garcia M; Kovácsházi C; Kittel A; Marcone S; Blanco A; Pallinger E; Hambalkó S; Piulats Rodriguez JM; Ferdinandy P; O'Sullivan J; Matallanas D; Jensen LD; Giricz Z; Kennedy BN
Open Res Eur; 2023; 3():88. PubMed ID: 37981907
[TBL] [Abstract][Full Text] [Related]
10. Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo.
Wainberg ZA; Anghel A; Desai AJ; Ayala R; Luo T; Safran B; Fejzo MS; Hecht JR; Slamon DJ; Finn RS
Clin Cancer Res; 2010 Mar; 16(5):1509-19. PubMed ID: 20179222
[TBL] [Abstract][Full Text] [Related]
11. A preclinical evaluation of the MEK inhibitor refametinib in HER2-positive breast cancer cell lines including those with acquired resistance to trastuzumab or lapatinib.
O'Shea J; Cremona M; Morgan C; Milewska M; Holmes F; Espina V; Liotta L; O'Shaughnessy J; Toomey S; Madden SF; Carr A; Elster N; Hennessy BT; Eustace AJ
Oncotarget; 2017 Oct; 8(49):85120-85135. PubMed ID: 29156708
[TBL] [Abstract][Full Text] [Related]
12. Targeting primary and metastatic uveal melanoma with a G protein inhibitor.
Onken MD; Makepeace CM; Kaltenbronn KM; Choi J; Hernandez-Aya L; Weilbaecher KN; Piggott KD; Rao PK; Yuede CM; Dixon AJ; Osei-Owusu P; Cooper JA; Blumer KJ
J Biol Chem; 2021; 296():100403. PubMed ID: 33577798
[TBL] [Abstract][Full Text] [Related]
13. Depsipeptide inhibits migration of primary and metastatic uveal melanoma cell lines in vitro: a potential strategy for uveal melanoma.
Klisovic DD; Klisovic MI; Effron D; Liu S; Marcucci G; Katz SE
Melanoma Res; 2005 Jun; 15(3):147-53. PubMed ID: 15917695
[TBL] [Abstract][Full Text] [Related]
14. High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells.
Slater K; Heeran AB; Garcia-Mulero S; Kalirai H; Sanz-Pamplona R; Rahman A; Al-Attar N; Helmi M; O'Connell F; Bosch R; Portela A; Villanueva A; Gallagher WM; Jensen LD; Piulats JM; Coupland SE; O'Sullivan J; Kennedy BN
Cancers (Basel); 2020 Oct; 12(10):. PubMed ID: 33066024
[TBL] [Abstract][Full Text] [Related]
15. Overexpression of microRNA-130a represses uveal melanoma cell migration and invasion through inactivation of the Wnt/β-catenin signaling pathway by downregulating USP6.
Wu S; Han M; Zhang C
Cancer Gene Ther; 2022 Jul; 29(7):930-939. PubMed ID: 34522027
[TBL] [Abstract][Full Text] [Related]
16. Dual HER2 targeting impedes growth of HER2 gene-amplified uterine serous carcinoma xenografts.
Groeneweg JW; Hernandez SF; Byron VF; DiGloria CM; Lopez H; Scialabba V; Kim M; Zhang L; Borger DR; Tambouret R; Foster R; Rueda BR; Growdon WB
Clin Cancer Res; 2014 Dec; 20(24):6517-6528. PubMed ID: 25294905
[TBL] [Abstract][Full Text] [Related]
17. Dual Targeting of CDK4/6 and cMET in Metastatic Uveal Melanoma.
Ohara M; Saito K; Kageyama K; Terai M; Cheng H; Aplin AE; Sato T
Cancers (Basel); 2021 Mar; 13(5):. PubMed ID: 33806615
[TBL] [Abstract][Full Text] [Related]
18. MEK inhibition increases lapatinib sensitivity via modulation of FOXM1.
Gayle SS; Castellino RC; Buss MC; Nahta R
Curr Med Chem; 2013; 20(19):2486-99. PubMed ID: 23531216
[TBL] [Abstract][Full Text] [Related]
19. Preclinical evaluation of drug combinations identifies co-inhibition of Bcl-2/XL/W and MDM2 as a potential therapy in uveal melanoma.
Decaudin D; Frisch Dit Leitz E; Nemati F; Tarin M; Naguez A; Zerara M; Marande B; Vivet-Noguer R; Halilovic E; Fabre C; Jochemsen A; Roman-Roman S; Alsafadi S
Eur J Cancer; 2020 Feb; 126():93-103. PubMed ID: 31927215
[TBL] [Abstract][Full Text] [Related]
20. Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression.
Nencioni A; Cea M; Garuti A; Passalacqua M; Raffaghello L; Soncini D; Moran E; Zoppoli G; Pistoia V; Patrone F; Ballestrero A
PLoS One; 2010 Feb; 5(2):e9024. PubMed ID: 20126311
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
