These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
6. Tethered Agonism: A Common Activation Mechanism of Adhesion GPCRs. Liebscher I; Schöneberg T Handb Exp Pharmacol; 2016; 234():111-125. PubMed ID: 27832486 [TBL] [Abstract][Full Text] [Related]
7. A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133. Liebscher I; Schön J; Petersen SC; Fischer L; Auerbach N; Demberg LM; Mogha A; Cöster M; Simon KU; Rothemund S; Monk KR; Schöneberg T Cell Rep; 2014 Dec; 9(6):2018-26. PubMed ID: 25533341 [TBL] [Abstract][Full Text] [Related]
8. The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist. Wilde C; Fischer L; Lede V; Kirchberger J; Rothemund S; Schöneberg T; Liebscher I FASEB J; 2016 Feb; 30(2):666-73. PubMed ID: 26499266 [TBL] [Abstract][Full Text] [Related]
9. Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Xiao P; Guo S; Wen X; He QT; Lin H; Huang SM; Gou L; Zhang C; Yang Z; Zhong YN; Yang CC; Li Y; Gong Z; Tao XN; Yang ZS; Lu Y; Li SL; He JY; Wang C; Zhang L; Kong L; Sun JP; Yu X Nature; 2022 Apr; 604(7907):771-778. PubMed ID: 35418677 [TBL] [Abstract][Full Text] [Related]
10. Adhesion G protein-coupled receptors-Structure and functions. Thor D; Liebscher I Prog Mol Biol Transl Sci; 2023; 195():1-25. PubMed ID: 36707149 [TBL] [Abstract][Full Text] [Related]
11. Understanding the Structural Basis of Adhesion GPCR Functions. Araç D; Sträter N; Seiradake E Handb Exp Pharmacol; 2016; 234():67-82. PubMed ID: 27832484 [TBL] [Abstract][Full Text] [Related]
12. Classification, Nomenclature, and Structural Aspects of Adhesion GPCRs. Krishnan A; Nijmeijer S; de Graaf C; Schiöth HB Handb Exp Pharmacol; 2016; 234():15-41. PubMed ID: 27832482 [TBL] [Abstract][Full Text] [Related]
13. Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain. Beliu G; Altrichter S; Guixà-González R; Hemberger M; Brauer I; Dahse AK; Scholz N; Wieduwild R; Kuhlemann A; Batebi H; Seufert F; Pérez-Hernández G; Hildebrand PW; Sauer M; Langenhan T Mol Cell; 2021 Mar; 81(5):905-921.e5. PubMed ID: 33497605 [TBL] [Abstract][Full Text] [Related]
15. GAIN domain-mediated cleavage is required for activation of G protein-coupled receptor 56 (GPR56) by its natural ligands and a small-molecule agonist. Zhu B; Luo R; Jin P; Li T; Oak HC; Giera S; Monk KR; Lak P; Shoichet BK; Piao X J Biol Chem; 2019 Dec; 294(50):19246-19254. PubMed ID: 31628191 [TBL] [Abstract][Full Text] [Related]
16. The Evolutionary History of Vertebrate Adhesion GPCRs and Its Implication on Their Classification. Wittlake A; Prömel S; Schöneberg T Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34769233 [TBL] [Abstract][Full Text] [Related]
17. Conformational transitions and activation of the adhesion receptor CD97. Mao C; Zhao RJ; Dong YJ; Gao M; Chen LN; Zhang C; Xiao P; Guo J; Qin J; Shen DD; Ji SY; Zang SK; Zhang H; Wang WW; Shen Q; Sun JP; Zhang Y Mol Cell; 2024 Feb; 84(3):570-583.e7. PubMed ID: 38215752 [TBL] [Abstract][Full Text] [Related]
18. Emerging roles of adhesion G protein-coupled receptors. Rosa M; Noel T; Harris M; Ladds G Biochem Soc Trans; 2021 Aug; 49(4):1695-1709. PubMed ID: 34282836 [TBL] [Abstract][Full Text] [Related]
19. Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors. Dates AN; Jones DTD; Smith JS; Skiba MA; Rich MF; Burruss MM; Kruse AC; Blacklow SC Cell Chem Biol; 2024 Aug; 31(8):1542-1553.e4. PubMed ID: 38608683 [TBL] [Abstract][Full Text] [Related]
20. Adhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms. Monk KR; Hamann J; Langenhan T; Nijmeijer S; Schöneberg T; Liebscher I Mol Pharmacol; 2015 Sep; 88(3):617-23. PubMed ID: 25956432 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]