These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 38044090)

  • 1. Framework-Directed Amino-Acid Insertions Generated over 55-Fold Affinity-Matured Antibody Fragments That Enabled Sensitive Luminescent Immunoassays of Cortisol.
    Kiguchi Y; Morita I; Yamaki K; Takegami S; Kobayashi N
    Biol Pharm Bull; 2023; 46(12):1661-1665. PubMed ID: 38044090
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NanoLuc luciferase as a suitable fusion partner of recombinant antibody fragments for developing sensitive luminescent immunoassays.
    Oyama H; Kiguchi Y; Morita I; Miyashita T; Ichimura A; Miyaoka H; Izumi A; Terasawa S; Osumi N; Tanaka H; Niwa T; Kobayashi N
    Anal Chim Acta; 2021 May; 1161():238180. PubMed ID: 33896564
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Single-Step "Breeding" Generated a Diagnostic Anti-cortisol Antibody Fragment with Over 30-Fold Enhanced Affinity.
    Oyama H; Morita I; Kiguchi Y; Morishita T; Fukushima S; Nishimori Y; Niwa T; Kobayashi N
    Biol Pharm Bull; 2017; 40(12):2191-2198. PubMed ID: 29199242
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Retrieving Dissociation-Resistant Antibody Mutants: An Efficient Strategy for Developing Immunoassays with Improved Sensitivities.
    Kiguchi Y; Morita I; Tsuruno A; Kobayashi N
    Biol Pharm Bull; 2022; 45(10):1432-1437. PubMed ID: 36184500
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [A Novel System for Discovering High-affinity Antibody Mutants That Enables Immunoassays with Higher Sensitivities -Development and Application of Clonal Array Profiling (CAP)].
    Kiguchi Y
    Yakugaku Zasshi; 2022; 142(11):1153-1159. PubMed ID: 36328444
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gaussia Luciferase as a Genetic Fusion Partner with Antibody Fragments for Sensitive Immunoassay Monitoring of Clinical Biomarkers.
    Oyama H; Morita I; Kiguchi Y; Miyake S; Moriuchi A; Akisada T; Niwa T; Kobayashi N
    Anal Chem; 2015 Dec; 87(24):12387-95. PubMed ID: 26625180
    [TBL] [Abstract][Full Text] [Related]  

  • 7. One-Shot In Vitro Evolution Generated an Antibody Fragment for Testing Urinary Cotinine with More Than 40-Fold Enhanced Affinity.
    Oyama H; Morita I; Kiguchi Y; Banzono E; Ishii K; Kubo S; Watanabe Y; Hirai A; Kaede C; Ohta M; Kobayashi N
    Anal Chem; 2017 Jan; 89(1):988-995. PubMed ID: 27983781
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antibody Fragments for On-Site Testing of Cannabinoids Generated via in Vitro Affinity Maturation.
    Morita I; Oyama H; Yasuo M; Matsuda K; Katagi K; Ito A; Tatsuda H; Tanaka H; Morimoto S; Kobayashi N
    Biol Pharm Bull; 2017; 40(2):174-181. PubMed ID: 28154257
    [TBL] [Abstract][Full Text] [Related]  

  • 9. "Breeding" diagnostic antibodies for higher assay performance: a 250-fold affinity-matured antibody mutant targeting a small biomarker.
    Oyama H; Yamaguchi S; Nakata S; Niwa T; Kobayashi N
    Anal Chem; 2013 May; 85(10):4930-7. PubMed ID: 23631394
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The V
    Kiguchi Y; Oyama H; Morita I; Nagata Y; Umezawa N; Kobayashi N
    Sci Rep; 2021 Apr; 11(1):8201. PubMed ID: 33859250
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Clonal array profiling of scFv-displaying phages for high-throughput discovery of affinity-matured antibody mutants.
    Kiguchi Y; Oyama H; Morita I; Morikawa M; Nakano A; Fujihara W; Inoue Y; Sasaki M; Saijo Y; Kanemoto Y; Murayama K; Baba Y; Takeuchi A; Kobayashi N
    Sci Rep; 2020 Aug; 10(1):14103. PubMed ID: 32839506
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recombinant single-chain Fv fragments carrying C-terminal cysteine residues: production of bivalent and biotinylated miniantibodies.
    Kipriyanov SM; Dübel S; Breitling F; Kontermann RE; Little M
    Mol Immunol; 1994 Oct; 31(14):1047-58. PubMed ID: 7935496
    [TBL] [Abstract][Full Text] [Related]  

  • 13. More than 370-Fold Increase in Antibody Affinity to Estradiol-17β by Exploring Substitutions in the V
    Morita I; Kiguchi Y; Nakamura S; Yoshida A; Kubo H; Ishida M; Oyama H; Kobayashi N
    Biol Pharm Bull; 2022; 45(7):851-855. PubMed ID: 35786593
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Two-step in vitro antibody affinity maturation enables estradiol-17beta assays with more than 10-fold higher sensitivity.
    Kobayashi N; Oyama H; Kato Y; Goto J; Söderlind E; Borrebaeck CA
    Anal Chem; 2010 Feb; 82(3):1027-38. PubMed ID: 20047279
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fluorophor-linked immunosorbent assay: a time- and cost-saving method for the characterization of antibody fragments using a fusion protein of a single-chain antibody fragment and enhanced green fluorescent protein.
    Oelschlaeger P; Srikant-Iyer S; Lange S; Schmitt J; Schmid RD
    Anal Biochem; 2002 Oct; 309(1):27-34. PubMed ID: 12381358
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selection of single-chain variable fragment antibodies against fenitrothion by ribosome display.
    Luo Y; Xia Y
    Anal Biochem; 2012 Feb; 421(1):130-7. PubMed ID: 22138186
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Seeking high-priority mutations enabling successful antibody-breeding: systematic analysis of a mutant that gained over 100-fold enhanced affinity.
    Oyama H; Kiguchi Y; Morita I; Yamamoto C; Higashi Y; Taguchi M; Tagawa T; Enami Y; Takamine Y; Hasegawa H; Takeuchi A; Kobayashi N
    Sci Rep; 2020 Mar; 10(1):4807. PubMed ID: 32179767
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Generation of bioluminescent enzyme immunoassay for ferritin by single-chain variable fragment and its NanoLuc luciferase fusion.
    He Q; Yang L; Lin M; Yang H; Cui X; McCoy MR; Hammock BD; Fang Y; Zhao S
    Anal Bioanal Chem; 2022 Sep; 414(23):6939-6946. PubMed ID: 35945290
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Efficient refolding and immobilization of PMMA-tag-fused single-chain Fv antibodies for sensitive immunological detection on a PMMA plate.
    Kumada Y; Ishikawa Y; Fujiwara Y; Takeda R; Miyamoto R; Niwa D; Momose S; Kang B; Kishimoto M
    J Immunol Methods; 2014 Sep; 411():1-10. PubMed ID: 24910412
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of humanization by variable domain resurfacing on the antiviral activity of a single-chain antibody against respiratory syncytial virus.
    Delagrave S; Catalan J; Sweet C; Drabik G; Henry A; Rees A; Monath TP; Guirakhoo F
    Protein Eng; 1999 Apr; 12(4):357-62. PubMed ID: 10325407
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.