184 related articles for article (PubMed ID: 38055822)
1. RAD54L2 counters TOP2-DNA adducts to promote genome stability.
D'Alessandro G; Morales-Juarez DA; Richards SL; Nitiss KC; Serrano-Benitez A; Wang J; Thomas JC; Gupta V; Voigt A; Belotserkovskaya R; Goh CG; Bowden AR; Galanty Y; Beli P; Nitiss JL; Zagnoli-Vieira G; Jackson SP
Sci Adv; 2023 Dec; 9(49):eadl2108. PubMed ID: 38055822
[TBL] [Abstract][Full Text] [Related]
2. Genome-Wide CRISPR Screens Reveal ZATT as a Synthetic Lethal Target of TOP2-Poison Etoposide That Can Act in a TDP2-Independent Pathway.
Park JM; Zhang H; Nie L; Wang C; Huang M; Feng X; Tang M; Chen Z; Xiong Y; Lee N; Li S; Yin L; Hart T; Chen J
Int J Mol Sci; 2023 Mar; 24(7):. PubMed ID: 37047518
[TBL] [Abstract][Full Text] [Related]
3. Repair of trapped topoisomerase II covalent cleavage complexes: Novel proteasome-independent mechanisms.
Tsuda M; Kitamasu K; Hosokawa S; Nakano T; Ide H
Nucleosides Nucleotides Nucleic Acids; 2020; 39(1-3):170-184. PubMed ID: 31608820
[TBL] [Abstract][Full Text] [Related]
4. RAD54L2-mediated DNA damage avoidance pathway specifically preserves genome integrity in response to topoisomerase 2 poisons.
Zhang H; Xiong Y; Sun Y; Park JM; Su D; Feng X; Keast S; Tang M; Huang M; Wang C; Srivastava M; Yang C; Zhu D; Chen Z; Li S; Yin L; Pommier Y; Chen J
Sci Adv; 2023 Dec; 9(49):eadi6681. PubMed ID: 38055811
[TBL] [Abstract][Full Text] [Related]
5. ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
Schellenberg MJ; Lieberman JA; Herrero-Ruiz A; Butler LR; Williams JG; Muñoz-Cabello AM; Mueller GA; London RE; Cortés-Ledesma F; Williams RS
Science; 2017 Sep; 357(6358):1412-1416. PubMed ID: 28912134
[TBL] [Abstract][Full Text] [Related]
6. Proteolytic degradation of topoisomerase II (Top2) enables the processing of Top2·DNA and Top2·RNA covalent complexes by tyrosyl-DNA-phosphodiesterase 2 (TDP2).
Gao R; Schellenberg MJ; Huang SY; Abdelmalak M; Marchand C; Nitiss KC; Nitiss JL; Williams RS; Pommier Y
J Biol Chem; 2014 Jun; 289(26):17960-9. PubMed ID: 24808172
[TBL] [Abstract][Full Text] [Related]
7. Depletion of tyrosyl DNA phosphodiesterase 2 activity enhances etoposide-mediated double-strand break formation and cell killing.
Kont YS; Dutta A; Mallisetty A; Mathew J; Minas T; Kraus C; Dhopeshwarkar P; Kallakury B; Mitra S; Üren A; Adhikari S
DNA Repair (Amst); 2016 Jul; 43():38-47. PubMed ID: 27235629
[TBL] [Abstract][Full Text] [Related]
8. Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes.
Lee KC; Swan RL; Sondka Z; Padget K; Cowell IG; Austin CA
Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30011940
[TBL] [Abstract][Full Text] [Related]
9. TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands.
Al Mahmud MR; Ishii K; Bernal-Lozano C; Delgado-Sainz I; Toi M; Akamatsu S; Fukumoto M; Watanabe M; Takeda S; Cortés-Ledesma F; Sasanuma H
Genes Cells; 2020 Jul; 25(7):450-465. PubMed ID: 32277721
[TBL] [Abstract][Full Text] [Related]
10. TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
Gómez-Herreros F; Romero-Granados R; Zeng Z; Alvarez-Quilón A; Quintero C; Ju L; Umans L; Vermeire L; Huylebroeck D; Caldecott KW; Cortés-Ledesma F
PLoS Genet; 2013; 9(3):e1003226. PubMed ID: 23505375
[TBL] [Abstract][Full Text] [Related]
11. Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity.
Sciascia N; Wu W; Zong D; Sun Y; Wong N; John S; Wangsa D; Ried T; Bunting SF; Pommier Y; Nussenzweig A
Elife; 2020 Feb; 9():. PubMed ID: 32057297
[TBL] [Abstract][Full Text] [Related]
12. Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA.
Morimoto S; Tsuda M; Bunch H; Sasanuma H; Austin C; Takeda S
Genes (Basel); 2019 Oct; 10(11):. PubMed ID: 31671674
[TBL] [Abstract][Full Text] [Related]
13. Molecular mechanisms of topoisomerase 2 DNA-protein crosslink resolution.
Riccio AA; Schellenberg MJ; Williams RS
Cell Mol Life Sci; 2020 Jan; 77(1):81-91. PubMed ID: 31728578
[TBL] [Abstract][Full Text] [Related]
14. BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes.
Sasanuma H; Tsuda M; Morimoto S; Saha LK; Rahman MM; Kiyooka Y; Fujiike H; Cherniack AD; Itou J; Callen Moreu E; Toi M; Nakada S; Tanaka H; Tsutsui K; Yamada S; Nussenzweig A; Takeda S
Proc Natl Acad Sci U S A; 2018 Nov; 115(45):E10642-E10651. PubMed ID: 30352856
[TBL] [Abstract][Full Text] [Related]
15. MDM2 provides TOP2 poison resistance by promoting proteolysis of TOP2βcc in a p53-independent manner.
Shu J; Jiang J; Wang X; Yang X; Zhao G; Cai T
Cell Death Dis; 2024 Jan; 15(1):83. PubMed ID: 38263255
[TBL] [Abstract][Full Text] [Related]
16. Physiological concentrations of glucocorticoids induce pathological DNA double-strand breaks.
Akter S; Shimba A; Ikuta K; Mahmud MRA; Yamada S; Sasanuma H; Tsuda M; Sone M; Ago Y; Murai K; Tanaka H; Takeda S
Genes Cells; 2023 Jan; 28(1):53-67. PubMed ID: 36415926
[TBL] [Abstract][Full Text] [Related]
17. Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding.
Shimizu N; Hamada Y; Morozumi R; Yamamoto J; Iwai S; Sugiyama KI; Ide H; Tsuda M
J Biol Chem; 2023 Aug; 299(8):104988. PubMed ID: 37392847
[TBL] [Abstract][Full Text] [Related]
18. Untangling trapped topoisomerases with tyrosyl-DNA phosphodiesterases.
Zagnoli-Vieira G; Caldecott KW
DNA Repair (Amst); 2020 Oct; 94():102900. PubMed ID: 32653827
[TBL] [Abstract][Full Text] [Related]
19. TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage.
Zeng Z; Cortés-Ledesma F; El Khamisy SF; Caldecott KW
J Biol Chem; 2011 Jan; 286(1):403-9. PubMed ID: 21030584
[TBL] [Abstract][Full Text] [Related]
20. Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Schellenberg MJ; Perera L; Strom CN; Waters CA; Monian B; Appel CD; Vilas CK; Williams JG; Ramsden DA; Williams RS
Nucleic Acids Res; 2016 May; 44(8):3829-44. PubMed ID: 27060144
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
