143 related articles for article (PubMed ID: 38056464)
1. Bexmarilimab-induced macrophage activation leads to treatment benefit in solid tumors: The phase I/II first-in-human MATINS trial.
Rannikko JH; Verlingue L; de Miguel M; Pasanen A; Robbrecht D; Skytta T; Iivanainen S; Shetty S; Ma YT; Graham DM; Arora SP; Jaakkola P; Yap C; Xiang Y; Mandelin J; Karvonen MK; Jalkanen J; Karaman S; Koivunen JP; Minchom A; Hollmén M; Bono P
Cell Rep Med; 2023 Dec; 4(12):101307. PubMed ID: 38056464
[TBL] [Abstract][Full Text] [Related]
2. Nonclinical Characterization of Bexmarilimab, a Clever-1-Targeting Antibody for Supporting Immune Defense Against Cancers.
Hollmén M; Maksimow M; Rannikko JH; Karvonen MK; Vainio M; Jalkanen S; Jalkanen M; Mandelin J
Mol Cancer Ther; 2022 Jul; 21(7):1207-1218. PubMed ID: 35500016
[TBL] [Abstract][Full Text] [Related]
3. Systemic Blockade of Clever-1 Elicits Lymphocyte Activation Alongside Checkpoint Molecule Downregulation in Patients with Solid Tumors: Results from a Phase I/II Clinical Trial.
Virtakoivu R; Rannikko JH; Viitala M; Vaura F; Takeda A; Lönnberg T; Koivunen J; Jaakkola P; Pasanen A; Shetty S; de Jonge MJA; Robbrecht D; Ma YT; Skyttä T; Minchom A; Jalkanen S; Karvonen MK; Mandelin J; Bono P; Hollmén M
Clin Cancer Res; 2021 Aug; 27(15):4205-4220. PubMed ID: 34078651
[TBL] [Abstract][Full Text] [Related]
4. Bexmarilimab Activates Human Tumor-Associated Macrophages to Support Adaptive Immune Responses in Interferon-Poor Immune Microenvironments.
Rannikko JH; Bono P; Hynninen J; Hollmén M
Cancer Immunol Res; 2024 Jan; 12(1):48-59. PubMed ID: 37922365
[TBL] [Abstract][Full Text] [Related]
5. Preclinical Evaluation of
Moisio O; Virta J; Yatkin E; Liljenbäck H; Palani S; Viitanen R; Miner MWG; Oikonen V; Tolvanen T; Vugts DJ; Taimen P; Li XG; Hollmén M; Jalkanen S; Roivainen A
J Nucl Med; 2023 Apr; 64(4):555-560. PubMed ID: 36302655
[TBL] [Abstract][Full Text] [Related]
6. Safety, tolerability, pharmacokinetics, and pharmacodynamics of the afucosylated, humanized anti-EPHA2 antibody DS-8895a: a first-in-human phase I dose escalation and dose expansion study in patients with advanced solid tumors.
Shitara K; Satoh T; Iwasa S; Yamaguchi K; Muro K; Komatsu Y; Nishina T; Esaki T; Hasegawa J; Kakurai Y; Kamiyama E; Nakata T; Nakamura K; Sakaki H; Hyodo I
J Immunother Cancer; 2019 Aug; 7(1):219. PubMed ID: 31412935
[TBL] [Abstract][Full Text] [Related]
7. Intratumoral OH2, an oncolytic herpes simplex virus 2, in patients with advanced solid tumors: a multicenter, phase I/II clinical trial.
Zhang B; Huang J; Tang J; Hu S; Luo S; Luo Z; Zhou F; Tan S; Ying J; Chang Q; Zhang R; Geng C; Wu D; Gu X; Liu B
J Immunother Cancer; 2021 Apr; 9(4):. PubMed ID: 33837053
[TBL] [Abstract][Full Text] [Related]
8. First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid tumors and lymphomas.
Piha-Paul SA; Geva R; Tan TJ; Lim DW; Hierro C; Doi T; Rahma O; Lesokhin A; Luke JJ; Otero J; Nardi L; Singh A; Xyrafas A; Chen X; Mataraza J; Bedard PL
J Immunother Cancer; 2021 Aug; 9(8):. PubMed ID: 34389618
[TBL] [Abstract][Full Text] [Related]
9. Clever-1/stabilin-1 controls cancer growth and metastasis.
Karikoski M; Marttila-Ichihara F; Elima K; Rantakari P; Hollmén M; Kelkka T; Gerke H; Huovinen V; Irjala H; Holmdahl R; Salmi M; Jalkanen S
Clin Cancer Res; 2014 Dec; 20(24):6452-64. PubMed ID: 25320356
[TBL] [Abstract][Full Text] [Related]
10. Evorpacept alone and in combination with pembrolizumab or trastuzumab in patients with advanced solid tumours (ASPEN-01): a first-in-human, open-label, multicentre, phase 1 dose-escalation and dose-expansion study.
Lakhani NJ; Chow LQM; Gainor JF; LoRusso P; Lee KW; Chung HC; Lee J; Bang YJ; Hodi FS; Kim WS; Santana-Davila R; Fanning P; Squifflet P; Jin F; Kuo TC; Wan HI; Pons J; Randolph SS; Messersmith WA
Lancet Oncol; 2021 Dec; 22(12):1740-1751. PubMed ID: 34793719
[TBL] [Abstract][Full Text] [Related]
11. Phase I, first-in-human study of MSC-1 (AZD0171), a humanized anti-leukemia inhibitory factor monoclonal antibody, for advanced solid tumors.
Borazanci E; Schram AM; Garralda E; Brana I; Vieito Villar M; Spreafico A; Oliva M; Lakhani NJ; Hoffman K; Hallett RM; Maetzel D; Hua F; Hilbert J; Giblin P; Anido J; Kelly A; Vickers PJ; Wasserman R; Seoane J; Siu LL; Hyman DM; Hoff DV; Tabernero J
ESMO Open; 2022 Aug; 7(4):100530. PubMed ID: 35921760
[TBL] [Abstract][Full Text] [Related]
12. First-in-human phase 1 study of MK-1248, an anti-glucocorticoid-induced tumor necrosis factor receptor agonist monoclonal antibody, as monotherapy or with pembrolizumab in patients with advanced solid tumors.
Geva R; Voskoboynik M; Dobrenkov K; Mayawala K; Gwo J; Wnek R; Chartash E; Long GV
Cancer; 2020 Nov; 126(22):4926-4935. PubMed ID: 32809217
[TBL] [Abstract][Full Text] [Related]
13. Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy.
Prokopi A; Tripp CH; Tummers B; Hornsteiner F; Spoeck S; Crawford JC; Clements DR; Efremova M; Hutter K; Bellmann L; Cappellano G; Cadilha BL; Kobold S; Boon L; Ortner D; Trajanoski Z; Chen S; de Gruijl TD; Idoyaga J; Green DR; Stoitzner P
J Immunother Cancer; 2021 Jan; 9(1):. PubMed ID: 33408092
[TBL] [Abstract][Full Text] [Related]
14. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates.
Brahmer JR; Drake CG; Wollner I; Powderly JD; Picus J; Sharfman WH; Stankevich E; Pons A; Salay TM; McMiller TL; Gilson MM; Wang C; Selby M; Taube JM; Anders R; Chen L; Korman AJ; Pardoll DM; Lowy I; Topalian SL
J Clin Oncol; 2010 Jul; 28(19):3167-75. PubMed ID: 20516446
[TBL] [Abstract][Full Text] [Related]
15. Immunotherapeutic Blockade of Macrophage Clever-1 Reactivates the CD8
Viitala M; Virtakoivu R; Tadayon S; Rannikko J; Jalkanen S; Hollmén M
Clin Cancer Res; 2019 Jun; 25(11):3289-3303. PubMed ID: 30755440
[TBL] [Abstract][Full Text] [Related]
16. Phase I study with ONCOS-102 for the treatment of solid tumors - an evaluation of clinical response and exploratory analyses of immune markers.
Ranki T; Pesonen S; Hemminki A; Partanen K; Kairemo K; Alanko T; Lundin J; Linder N; Turkki R; Ristimäki A; Jäger E; Karbach J; Wahle C; Kankainen M; Backman C; von Euler M; Haavisto E; Hakonen T; Heiskanen R; Jaderberg M; Juhila J; Priha P; Suoranta L; Vassilev L; Vuolanto A; Joensuu T
J Immunother Cancer; 2016; 4():17. PubMed ID: 26981247
[TBL] [Abstract][Full Text] [Related]
17. A first-in-human, open-label, dose-escalation and dose-expansion phase I study to evaluate the safety, tolerability, pharmacokinetics/pharmacodynamics, and antitumor activity of QL1604, a humanized anti-PD-1 mAb, in patients with advanced or metastatic solid tumors.
Huang Z; Xu Y; Hong W; Gong L; Chen K; Qin J; Xie F; Wang F; Tian X; Meng X; Feng W; Li L; Zhang B; Kang X; Fan Y
Front Immunol; 2023; 14():1258573. PubMed ID: 37936687
[TBL] [Abstract][Full Text] [Related]
18. First-in-human study of an OX40 (ivuxolimab) and 4-1BB (utomilumab) agonistic antibody combination in patients with advanced solid tumors.
Hamid O; Chiappori AA; Thompson JA; Doi T; Hu-Lieskovan S; Eskens FALM; Ros W; Diab A; Spano JP; Rizvi NA; Wasser JS; Angevin E; Ott PA; Forgie A; Yang W; Guo C; Chou J; El-Khoueiry AB
J Immunother Cancer; 2022 Oct; 10(10):. PubMed ID: 36302562
[TBL] [Abstract][Full Text] [Related]
19. Stabilin-1/CLEVER-1, a type 2 macrophage marker, is an adhesion and scavenging molecule on human placental macrophages.
Palani S; Maksimow M; Miiluniemi M; Auvinen K; Jalkanen S; Salmi M
Eur J Immunol; 2011 Jul; 41(7):2052-63. PubMed ID: 21480214
[TBL] [Abstract][Full Text] [Related]
20. Phase II trial of erlotinib and docetaxel in advanced and refractory hepatocellular and biliary cancers: Hoosier Oncology Group GI06-101.
Chiorean EG; Ramasubbaiah R; Yu M; Picus J; Bufill JA; Tong Y; Coleman N; Johnston EL; Currie C; Loehrer PJ
Oncologist; 2012; 17(1):13. PubMed ID: 22210086
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
