These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 38063257)

  • 1. Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease.
    Salcedo C; Pozo Garcia V; García-Adán B; Ameen AO; Gegelashvili G; Waagepetersen HS; Freude KK; Aldana BI
    J Neurochem; 2024 May; 168(5):822-840. PubMed ID: 38063257
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease.
    Salcedo C; Wagner A; Andersen JV; Vinten KT; Waagepetersen HS; Schousboe A; Freude KK; Aldana BI
    Neurochem Res; 2021 Oct; 46(10):2676-2686. PubMed ID: 33710537
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease.
    Salcedo C; Andersen JV; Vinten KT; Pinborg LH; Waagepetersen HS; Freude KK; Aldana BI
    Front Aging Neurosci; 2021; 13():736580. PubMed ID: 34603012
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease.
    Andersen JV; Christensen SK; Westi EW; Diaz-delCastillo M; Tanila H; Schousboe A; Aldana BI; Waagepetersen HS
    Neurobiol Dis; 2021 Jan; 148():105198. PubMed ID: 33242587
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
    Ochalek A; Mihalik B; Avci HX; Chandrasekaran A; Téglási A; Bock I; Giudice ML; Táncos Z; Molnár K; László L; Nielsen JE; Holst B; Freude K; Hyttel P; Kobolák J; Dinnyés A
    Alzheimers Res Ther; 2017 Dec; 9(1):90. PubMed ID: 29191219
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia.
    Aldana BI; Zhang Y; Jensen P; Chandrasekaran A; Christensen SK; Nielsen TT; Nielsen JE; Hyttel P; Larsen MR; Waagepetersen HS; Freude KK
    Mol Brain; 2020 Sep; 13(1):125. PubMed ID: 32928252
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ceftriaxone regulates glutamate production and vesicular assembly in presynaptic terminals through GLT-1 in APP/PS1 mice.
    Fan S; Li L; Xian X; Liu L; Gao J; Li W
    Neurobiol Learn Mem; 2021 Sep; 183():107480. PubMed ID: 34153453
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration.
    Andersen JV; Markussen KH; Jakobsen E; Schousboe A; Waagepetersen HS; Rosenberg PA; Aldana BI
    Neuropharmacology; 2021 Sep; 196():108719. PubMed ID: 34273389
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons.
    Aldana BI; Zhang Y; Lihme MF; Bak LK; Nielsen JE; Holst B; Hyttel P; Freude KK; Waagepetersen HS
    Neurochem Int; 2017 Jun; 106():48-61. PubMed ID: 28237843
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ.
    Kwart D; Gregg A; Scheckel C; Murphy EA; Paquet D; Duffield M; Fak J; Olsen O; Darnell RB; Tessier-Lavigne M
    Neuron; 2019 Oct; 104(2):256-270.e5. PubMed ID: 31416668
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability.
    Siman R; Reaume AG; Savage MJ; Trusko S; Lin YG; Scott RW; Flood DG
    J Neurosci; 2000 Dec; 20(23):8717-26. PubMed ID: 11102478
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neuronal Dynamics and miRNA Signaling Differ between SH-SY5Y
    Garcia G; Pinto S; Cunha M; Fernandes A; Koistinaho J; Brites D
    Cells; 2021 Sep; 10(9):. PubMed ID: 34572073
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Exploring the Role of PSEN Mutations in the Pathogenesis of Alzheimer's Disease.
    Kabir MT; Uddin MS; Setu JR; Ashraf GM; Bin-Jumah MN; Abdel-Daim MM
    Neurotox Res; 2020 Dec; 38(4):833-849. PubMed ID: 32556937
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression.
    Corsi GI; Gadekar VP; Haukedal H; Doncheva NT; Anthon C; Ambardar S; Palakodeti D; Hyttel P; Freude K; Seemann SE; Gorodkin J
    Neurobiol Dis; 2023 Mar; 178():105980. PubMed ID: 36572121
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived Astrocytes.
    Arnst N; Belio-Mairal P; García-González L; Arnaud L; Greetham L; Nivet E; Rivera S; Dityatev A
    Cells; 2021 Jul; 10(7):. PubMed ID: 34359875
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer's Disease Mutations.
    Woodruff G; Reyna SM; Dunlap M; Van Der Kant R; Callender JA; Young JE; Roberts EA; Goldstein LS
    Cell Rep; 2016 Oct; 17(3):759-773. PubMed ID: 27732852
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease.
    Andersen JV; Skotte NH; Christensen SK; Polli FS; Shabani M; Markussen KH; Haukedal H; Westi EW; Diaz-delCastillo M; Sun RC; Kohlmeier KA; Schousboe A; Gentry MS; Tanila H; Freude KK; Aldana BI; Mann M; Waagepetersen HS
    Cell Death Dis; 2021 Oct; 12(11):954. PubMed ID: 34657143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential effects of familial Alzheimer's disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity.
    Schilling S; Pradhan A; Heesch A; Helbig A; Blennow K; Koch C; Bertgen L; Koo EH; Brinkmalm G; Zetterberg H; Kins S; Eggert S
    Acta Neuropathol Commun; 2023 Jun; 11(1):87. PubMed ID: 37259128
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ceftriaxone Improves Cognitive Function and Upregulates GLT-1-Related Glutamate-Glutamine Cycle in APP/PS1 Mice.
    Fan S; Xian X; Li L; Yao X; Hu Y; Zhang M; Li W
    J Alzheimers Dis; 2018; 66(4):1731-1743. PubMed ID: 30452416
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel interaction between Alzheimer's disease-related protein presenilin 1 and glutamate transporter 1.
    Zoltowska KM; Maesako M; Meier J; Berezovska O
    Sci Rep; 2018 Jun; 8(1):8718. PubMed ID: 29880815
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.