BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 38063319)

  • 1. Design, Synthesis, and Bioactivity Evaluations of 3-Methylenechroman-2-one Derivatives as Thioredoxin Reductase (TrxR) Inhibitors.
    Nikitjuka A; Ozola M; Krims-Davis K; Žalubovskis R
    ChemMedChem; 2024 Feb; 19(3):e202300504. PubMed ID: 38063319
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exploration of 3,4-unsubstituted coumarins as thioredoxin reductase 1 inhibitors for cancer therapy.
    Nikitjuka A; Ozola M; Jackevica L; Bobrovs R; Žalubovskis R
    Org Biomol Chem; 2023 Dec; 21(48):9630-9639. PubMed ID: 38018884
    [TBL] [Abstract][Full Text] [Related]  

  • 3. May 1,2-Dithiolane-4-carboxylic Acid and Its Derivatives Serve as a Specific Thioredoxin Reductase 1 Inhibitor?
    Nikitjuka A; Krims-Davis K; Kaņepe-Lapsa I; Ozola M; Žalubovskis R
    Molecules; 2023 Sep; 28(18):. PubMed ID: 37764424
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of Michael acceptor-centric pharmacophores with substituents that yield strong thioredoxin reductase inhibitory character correlated to antiproliferative activity.
    Gan FF; Kaminska KK; Yang H; Liew CY; Leow PC; So CL; Tu LN; Roy A; Yap CW; Kang TS; Chui WK; Chew EH
    Antioxid Redox Signal; 2013 Oct; 19(11):1149-65. PubMed ID: 23311917
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sublethal concentrations of diverse gold compounds inhibit mammalian cytosolic thioredoxin reductase (TrxR1).
    Omata Y; Folan M; Shaw M; Messer RL; Lockwood PE; Hobbs D; Bouillaguet S; Sano H; Lewis JB; Wataha JC
    Toxicol In Vitro; 2006 Sep; 20(6):882-90. PubMed ID: 16510263
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity.
    Ng HL; Chen S; Chew EH; Chui WK
    Eur J Med Chem; 2016 Jun; 115():63-74. PubMed ID: 26994844
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of benzylidenecyclohexenones as TrxR inhibitors displaying high anticancer activity and inducing ROS, apoptosis, and autophagy.
    Qian J; Xu Z; Meng C; Liu J; Hsu PL; Li Y; Zhu W; Yang Y; Morris-Natschke SL; Lee KH; Zhang Y; Ling Y
    Eur J Med Chem; 2020 Oct; 204():112610. PubMed ID: 32736231
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and biological evaluation of a novel indoleamine 2,3-dioxigenase 1 (IDO1) and thioredoxin reductase (TrxR) dual inhibitor.
    Fan QZ; Zhou J; Zhu YB; He LJ; Miao DD; Zhang SP; Liu XP; Zhang C
    Bioorg Chem; 2020 Dec; 105():104401. PubMed ID: 33113415
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recent advances in the development of thioredoxin reductase inhibitors as anticancer agents.
    Liu Y; Li Y; Yu S; Zhao G
    Curr Drug Targets; 2012 Oct; 13(11):1432-44. PubMed ID: 22876886
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent Inhibition of Thioredoxin Reductase by the Rh Derivatives of Anticancer M(arene/Cp*)(NHC)Cl
    Truong D; Sullivan MP; Tong KKH; Steel TR; Prause A; Lovett JH; Andersen JW; Jamieson SMF; Harris HH; Ott I; Weekley CM; Hummitzsch K; Söhnel T; Hanif M; Metzler-Nolte N; Goldstone DC; Hartinger CG
    Inorg Chem; 2020 Mar; 59(5):3281-3289. PubMed ID: 32073260
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening.
    Ni Y; Luo Z; Lv Y; Ma S; Luo C; Du D
    Biochem Biophys Res Commun; 2023 Apr; 650():117-122. PubMed ID: 36780763
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thioredoxin reductase inhibitors: a patent review.
    Zhang B; Zhang J; Peng S; Liu R; Li X; Hou Y; Han X; Fang J
    Expert Opin Ther Pat; 2017 May; 27(5):547-556. PubMed ID: 27977313
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads.
    Kaminska KK; Bertrand HC; Tajima H; Stafford WC; Cheng Q; Chen W; Wells G; Arner ES; Chew EH
    Oncotarget; 2016 Jun; 7(26):40233-40251. PubMed ID: 27244886
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of curcumin analogues as potential thioredoxin reductase inhibitors.
    Qiu X; Liu Z; Shao WY; Liu X; Jing DP; Yu YJ; An LK; Huang SL; Bu XZ; Huang ZS; Gu LQ
    Bioorg Med Chem; 2008 Sep; 16(17):8035-41. PubMed ID: 18678491
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase.
    Hashemy SI; Ungerstedt JS; Zahedi Avval F; Holmgren A
    J Biol Chem; 2006 Apr; 281(16):10691-7. PubMed ID: 16481328
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ethaselen: a potent mammalian thioredoxin reductase 1 inhibitor and novel organoselenium anticancer agent.
    Wang L; Yang Z; Fu J; Yin H; Xiong K; Tan Q; Jin H; Li J; Wang T; Tang W; Yin J; Cai G; Liu M; Kehr S; Becker K; Zeng H
    Free Radic Biol Med; 2012 Mar; 52(5):898-908. PubMed ID: 22210352
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acetaminophen reactive intermediates target hepatic thioredoxin reductase.
    Jan YH; Heck DE; Dragomir AC; Gardner CR; Laskin DL; Laskin JD
    Chem Res Toxicol; 2014 May; 27(5):882-94. PubMed ID: 24661219
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel electrophilic amides amenable by the Ugi reaction perturb thioredoxin system via thioredoxin reductase 1 (TrxR1) inhibition: Identification of DVD-445 as a new lead compound for anticancer therapy.
    Jovanović M; Zhukovsky D; Podolski-Renić A; Domračeva I; Žalubovskis R; Senćanski M; Glišić S; Sharoyko V; Tennikova T; Dar'in D; Pešić M; Krasavin M
    Eur J Med Chem; 2019 Nov; 181():111580. PubMed ID: 31400708
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure modification and biological evaluation of indole-chalcone derivatives as anti-tumor agents through dual targeting tubulin and TrxR.
    Yan J; Xu Y; Jin X; Zhang Q; Ouyang F; Han L; Zhan M; Li X; Liang B; Huang X
    Eur J Med Chem; 2022 Jan; 227():113897. PubMed ID: 34649064
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Noble metal targeting of thioredoxin reductase--covalent complexes with thioredoxin and thioredoxin-related protein of 14 kDa triggered by cisplatin.
    Prast-Nielsen S; Cebula M; Pader I; Arnér ES
    Free Radic Biol Med; 2010 Dec; 49(11):1765-78. PubMed ID: 20851179
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.