BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 38071533)

  • 1. Utilizing a Dual Human Transporter MDCKII-MDR1-BCRP Cell Line to Assess Efflux at the Blood Brain Barrier.
    Colclough N; Alluri RV; Tucker JW; Gozalpour E; Li D; Du H; Li W; Harlfinger S; O'Neill DJ; Sproat GG; Chen K; Yan Y; McGinnity DF
    Drug Metab Dispos; 2024 Jan; 52(2):95-105. PubMed ID: 38071533
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization and Validation of Canine P-Glycoprotein-Deficient MDCK II Cell Lines for Efflux Substrate Screening.
    Ye D; Harder A; Fang Z; Weinheimer M; Laplanche L; Mezler M
    Pharm Res; 2020 Sep; 37(10):194. PubMed ID: 32918191
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of Human Breast Cancer Related Protein versus P-Glycoprotein as an Efflux Transporter for Benzylpenicillin: Potential Importance at the Blood-Brain Barrier.
    Li Y; Wu Q; Li C; Liu L; Du K; Shen J; Wu Y; Zhao X; Zhao M; Bao L; Gao J; Keep RF; Xiang J
    PLoS One; 2016; 11(6):e0157576. PubMed ID: 27300692
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Validation of Human MDR1-MDCK and BCRP-MDCK Cell Lines to Improve the Prediction of Brain Penetration.
    Feng B; West M; Patel NC; Wager T; Hou X; Johnson J; Tremaine L; Liras J
    J Pharm Sci; 2019 Jul; 108(7):2476-2483. PubMed ID: 30794795
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of Drug Transport in MDCKII-Wild Type, MDCKII-MDR1, MDCKII-BCRP and Caco-2 Cell Lines.
    Mukkavilli R; Jadhav G; Vangala S
    Curr Pharm Biotechnol; 2017; 18(14):1151-1158. PubMed ID: 29521222
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro transport of gimatecan (7-t-butoxyiminomethylcamptothecin) by breast cancer resistance protein, P-glycoprotein, and multidrug resistance protein 2.
    Marchetti S; Oostendorp RL; Pluim D; van Eijndhoven M; van Tellingen O; Schinkel AH; Versace R; Beijnen JH; Mazzanti R; Schellens JH
    Mol Cancer Ther; 2007 Dec; 6(12 Pt 1):3307-13. PubMed ID: 18089724
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of a high-resolution in vitro human MDR1-MDCK assay and in vivo studies in preclinical species to improve prediction of CNS drug penetration.
    Jiang L; Kumar S; Nuechterlein M; Reyes M; Tran D; Cabebe C; Chiang P; Reynolds J; Carrier S; Sun Y; Eddershaw P; Hay T; Chen W; Feng B
    Pharmacol Res Perspect; 2022 Feb; 10(1):e00932. PubMed ID: 35156331
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Investigation of MDR1-overexpressing cell lines to derive a quantitative prediction approach for brain disposition using in vitro efflux activities.
    Sato S; Tohyama K; Kosugi Y
    Eur J Pharm Sci; 2020 Jan; 142():105119. PubMed ID: 31682973
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT).
    Guo A; Marinaro W; Hu P; Sinko PJ
    Drug Metab Dispos; 2002 Apr; 30(4):457-63. PubMed ID: 11901101
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MDR1 and BCRP Transporter-Mediated Drug-Drug Interaction between Rilpivirine and Abacavir and Effect on Intestinal Absorption.
    Reznicek J; Ceckova M; Ptackova Z; Martinec O; Tupova L; Cerveny L; Staud F
    Antimicrob Agents Chemother; 2017 Sep; 61(9):. PubMed ID: 28696229
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expanding the Efflux In Vitro Assay Toolbox: A CRISPR-Cas9 Edited MDCK Cell Line with Human BCRP and Completely Lacking Canine MDR1.
    Wegler C; Gazit M; Issa K; Subramaniam S; Artursson P; Karlgren M
    J Pharm Sci; 2021 Jan; 110(1):388-396. PubMed ID: 33007277
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prediction of Human Brain Penetration of P-glycoprotein and Breast Cancer Resistance Protein Substrates Using In Vitro Transporter Studies and Animal Models.
    Feng B; Doran AC; Di L; West MA; Osgood SM; Mancuso JY; Shaffer CL; Tremaine L; Liras J
    J Pharm Sci; 2018 Aug; 107(8):2225-2235. PubMed ID: 29608887
    [TBL] [Abstract][Full Text] [Related]  

  • 13. (R)-[(11)C]verapamil is selectively transported by murine and human P-glycoprotein at the blood-brain barrier, and not by MRP1 and BCRP.
    Römermann K; Wanek T; Bankstahl M; Bankstahl JP; Fedrowitz M; Müller M; Löscher W; Kuntner C; Langer O
    Nucl Med Biol; 2013 Oct; 40(7):873-8. PubMed ID: 23845421
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Black ginger extract and its active compound, 5,7-dimethoxyflavone, increase intestinal drug absorption via efflux drug transporter inhibitions.
    Boonnop R; Meetam P; Siangjong L; Tuchinda P; Thongphasuk P; Soodvilai S; Soodvilai S
    Drug Metab Pharmacokinet; 2023 Jun; 50():100500. PubMed ID: 36948091
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The antiepileptic drug lamotrigine is a substrate of mouse and human breast cancer resistance protein (ABCG2).
    Römermann K; Helmer R; Löscher W
    Neuropharmacology; 2015 Jun; 93():7-14. PubMed ID: 25645391
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Harnessing Preclinical Data as a Predictive Tool for Human Brain Tissue Targeting.
    Patel NC; Feng B; Hou X; West MA; Trapa PE; Sciabola S; Verhoest P; Liras JL; Maurer TS; Wager TT
    ACS Chem Neurosci; 2021 Mar; 12(6):1007-1017. PubMed ID: 33651587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro assessment of the interactions of dopamine β-hydroxylase inhibitors with human P-glycoprotein and Breast Cancer Resistance Protein.
    Bicker J; Alves G; Fortuna A; Soares-da-Silva P; Falcão A
    Eur J Pharm Sci; 2018 May; 117():35-40. PubMed ID: 29428540
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of aripiprazole and its active metabolite dehydroaripiprazole on the activities of drug efflux transporters expressed both in the intestine and at the blood-brain barrier.
    Nagasaka Y; Oda K; Iwatsubo T; Kawamura A; Usui T
    Biopharm Drug Dispos; 2012 Sep; 33(6):304-15. PubMed ID: 22847220
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tetrahydrocannabinol and Its Major Metabolites Are Not (or Are Poor) Substrates or Inhibitors of Human P-Glycoprotein [ATP-Binding Cassette (ABC) B1] and Breast Cancer Resistance Protein (ABCG2).
    Chen X; Unadkat JD; Mao Q
    Drug Metab Dispos; 2021 Oct; 49(10):910-918. PubMed ID: 34326138
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ketamine Pharmacokinetics and Pharmacodynamics Are Altered by P-Glycoprotein and Breast Cancer Resistance Protein Efflux Transporters in Mice.
    Ganguly S; Panetta JC; Roberts JK; Schuetz EG
    Drug Metab Dispos; 2018 Jul; 46(7):1014-1022. PubMed ID: 29674491
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.