348 related articles for article (PubMed ID: 3807895)
1. Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine.
Elfarra AA; Lash LH; Anders MW
Mol Pharmacol; 1987 Feb; 31(2):208-12. PubMed ID: 3807895
[TBL] [Abstract][Full Text] [Related]
2. The role of mitochondrial matrix enzymes in the metabolism and toxicity of cysteine conjugates.
Stevens JL; Ayoubi N; Robbins JD
J Biol Chem; 1988 Mar; 263(7):3395-401. PubMed ID: 3343250
[TBL] [Abstract][Full Text] [Related]
3. Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine sulfoxide.
Lash LH; Sausen PJ; Duescher RJ; Cooley AJ; Elfarra AA
J Pharmacol Exp Ther; 1994 Apr; 269(1):374-83. PubMed ID: 8169843
[TBL] [Abstract][Full Text] [Related]
4. Purification of glutamine transaminase K/cysteine conjugate beta-lyase from rat renal cytosol based on hydrophobic interaction HPLC and gel permeation FPLC.
Yamauchi A; Stijntjes GJ; Commandeur JN; Vermeulen NP
Protein Expr Purif; 1993 Dec; 4(6):552-62. PubMed ID: 8286953
[TBL] [Abstract][Full Text] [Related]
5. Bioactivation of selenocysteine Se-conjugates by a highly purified rat renal cysteine conjugate beta-lyase/glutamine transaminase K.
Commandeur JN; Andreadou I; Rooseboom M; Out M; de Leur LJ; Groot E; Vermeulen NP
J Pharmacol Exp Ther; 2000 Aug; 294(2):753-61. PubMed ID: 10900257
[TBL] [Abstract][Full Text] [Related]
6. Purification and characterization of human kidney cytosolic cysteine conjugate beta-lyase activity.
Lash LH; Nelson RM; Van Dyke RA; Anders MW
Drug Metab Dispos; 1990; 18(1):50-4. PubMed ID: 2139845
[TBL] [Abstract][Full Text] [Related]
7. Glutamine transaminase K is not a major cysteine S-conjugate beta-lyase of rat kidney mitochondria: evidence that a high-molecular weight enzyme fulfills this role.
Abraham DG; Thomas RJ; Cooper AJ
Mol Pharmacol; 1995 Nov; 48(5):855-60. PubMed ID: 7476916
[TBL] [Abstract][Full Text] [Related]
8. Quantitation of multiple pathways for the metabolism of nephrotoxic cysteine conjugates using selective inhibitors of L-alpha-hydroxy acid oxidase (L-amino acid oxidase) and cysteine conjugate beta-lyase.
Stevens JL; Hatzinger PB; Hayden PJ
Drug Metab Dispos; 1989; 17(3):297-303. PubMed ID: 2568912
[TBL] [Abstract][Full Text] [Related]
9. Renal cysteine conjugate beta-lyase. Bioactivation of nephrotoxic cysteine S-conjugates in mitochondrial outer membrane.
Lash LH; Elfarra AA; Anders MW
J Biol Chem; 1986 May; 261(13):5930-5. PubMed ID: 3700378
[TBL] [Abstract][Full Text] [Related]
10. Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells.
McGoldrick TA; Lock EA; Rodilla V; Hawksworth GM
Arch Toxicol; 2003 Jul; 77(7):365-70. PubMed ID: 12700887
[TBL] [Abstract][Full Text] [Related]
11. Role of cysteine S-conjugate beta-lyase in the metabolism of cisplatin.
Zhang L; Hanigan MH
J Pharmacol Exp Ther; 2003 Sep; 306(3):988-94. PubMed ID: 12750429
[TBL] [Abstract][Full Text] [Related]
12. A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K.
Stevens JL; Robbins JD; Byrd RA
J Biol Chem; 1986 Nov; 261(33):15529-37. PubMed ID: 3782077
[TBL] [Abstract][Full Text] [Related]
13. The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants.
Cooper AJ
Neurochem Int; 2004 Jun; 44(8):557-77. PubMed ID: 15016471
[TBL] [Abstract][Full Text] [Related]
14. Cysteine conjugate toxicity, metabolism, and binding to macromolecules in isolated rat kidney mitochondria.
Hayden PJ; Stevens JL
Mol Pharmacol; 1990 Mar; 37(3):468-76. PubMed ID: 2314393
[TBL] [Abstract][Full Text] [Related]
15. Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells.
Lash LH; Anders MW
J Pharmacol Exp Ther; 1989 Feb; 248(2):531-7. PubMed ID: 2918469
[TBL] [Abstract][Full Text] [Related]
16. Aminotransferase, L-amino acid oxidase and beta-lyase reactions involving L-cysteine S-conjugates found in allium extracts. Relevance to biological activity?
Cooper AJ; Pinto JT
Biochem Pharmacol; 2005 Jan; 69(2):209-20. PubMed ID: 15627473
[TBL] [Abstract][Full Text] [Related]
17. Glutamine transaminase K and cysteine S-conjugate beta-lyase activity stains.
Abraham DG; Cooper AJ
Anal Biochem; 1991 Sep; 197(2):421-7. PubMed ID: 1723851
[TBL] [Abstract][Full Text] [Related]
18. Glutathione-dependent biosynthesis and bioactivation of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine, the glutathione and cysteine S-conjugates of dichloroacetylene, in rat tissues and subcellular fractions.
Patel N; Birner G; Dekant W; Anders MW
Drug Metab Dispos; 1994; 22(1):143-7. PubMed ID: 8149874
[TBL] [Abstract][Full Text] [Related]
19. Cysteine S-conjugates may act as kidney-selective prodrugs: formation of 6-mercaptopurine by the renal metabolism of S-(6-purinyl)-L-cysteine.
Hwang IY; Elfarra AA
J Pharmacol Exp Ther; 1989 Nov; 251(2):448-54. PubMed ID: 2810108
[TBL] [Abstract][Full Text] [Related]
20. Immunohistochemical localization of glutamine transaminase K, a rat kidney cysteine conjugate beta-lyase, and the relationship to the segment specificity of cysteine conjugate nephrotoxicity.
Jones TW; Qin C; Schaeffer VH; Stevens JL
Mol Pharmacol; 1988 Nov; 34(5):621-7. PubMed ID: 3193955
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]