217 related articles for article (PubMed ID: 38086799)
1. Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes.
Rönn T; Ofori JK; Perfilyev A; Hamilton A; Pircs K; Eichelmann F; Garcia-Calzon S; Karagiannopoulos A; Stenlund H; Wendt A; Volkov P; Schulze MB; Mulder H; Eliasson L; Ruhrmann S; Bacos K; Ling C
Nat Commun; 2023 Dec; 14(1):8040. PubMed ID: 38086799
[TBL] [Abstract][Full Text] [Related]
2. Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.
Dayeh T; Volkov P; Salö S; Hall E; Nilsson E; Olsson AH; Kirkpatrick CL; Wollheim CB; Eliasson L; Rönn T; Bacos K; Ling C
PLoS Genet; 2014 Mar; 10(3):e1004160. PubMed ID: 24603685
[TBL] [Abstract][Full Text] [Related]
3. Whole-Genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis.
Volkov P; Bacos K; Ofori JK; Esguerra JL; Eliasson L; Rönn T; Ling C
Diabetes; 2017 Apr; 66(4):1074-1085. PubMed ID: 28052964
[TBL] [Abstract][Full Text] [Related]
4. MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation.
Daneshpajooh M; Eliasson L; Bacos K; Ling C
Acta Diabetol; 2018 Dec; 55(12):1231-1235. PubMed ID: 30088095
[TBL] [Abstract][Full Text] [Related]
5. Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets.
Bacos K; Perfilyev A; Karagiannopoulos A; Cowan E; Ofori JK; Bertonnier-Brouty L; Rönn T; Lindqvist A; Luan C; Ruhrmann S; Ngara M; Nilsson Å; Gheibi S; Lyons CL; Lagerstedt JO; Barghouth M; Esguerra JL; Volkov P; Fex M; Mulder H; Wierup N; Krus U; Artner I; Eliasson L; Prasad RB; Cataldo LR; Ling C
J Clin Invest; 2023 Feb; 133(4):. PubMed ID: 36656641
[TBL] [Abstract][Full Text] [Related]
6. Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion.
Ling C; Del Guerra S; Lupi R; Rönn T; Granhall C; Luthman H; Masiello P; Marchetti P; Groop L; Del Prato S
Diabetologia; 2008 Apr; 51(4):615-22. PubMed ID: 18270681
[TBL] [Abstract][Full Text] [Related]
7. Does epigenetic dysregulation of pancreatic islets contribute to impaired insulin secretion and type 2 diabetes?
Dayeh T; Ling C
Biochem Cell Biol; 2015 Oct; 93(5):511-21. PubMed ID: 26369706
[TBL] [Abstract][Full Text] [Related]
8. Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes.
Sharoyko VV; Abels M; Sun J; Nicholas LM; Mollet IG; Stamenkovic JA; Göhring I; Malmgren S; Storm P; Fadista J; Spégel P; Metodiev MD; Larsson NG; Eliasson L; Wierup N; Mulder H
Hum Mol Genet; 2014 Nov; 23(21):5733-49. PubMed ID: 24916378
[TBL] [Abstract][Full Text] [Related]
9. Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes.
Yang BT; Dayeh TA; Volkov PA; Kirkpatrick CL; Malmgren S; Jing X; Renström E; Wollheim CB; Nitert MD; Ling C
Mol Endocrinol; 2012 Jul; 26(7):1203-12. PubMed ID: 22570331
[TBL] [Abstract][Full Text] [Related]
10. Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes.
Habibe JJ; Clemente-Olivo MP; Scheithauer TPM; Rampanelli E; Herrema H; Vos M; Mieremet A; Nieuwdorp M; van Raalte DH; Eringa EC; de Vries CJM
Diabetologia; 2022 Oct; 65(10):1721-1733. PubMed ID: 35802167
[TBL] [Abstract][Full Text] [Related]
11. Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.
Hall E; Volkov P; Dayeh T; Bacos K; Rönn T; Nitert MD; Ling C
BMC Med; 2014 Jun; 12():103. PubMed ID: 24953961
[TBL] [Abstract][Full Text] [Related]
12. HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells.
Daneshpajooh M; Bacos K; Bysani M; Bagge A; Ottosson Laakso E; Vikman P; Eliasson L; Mulder H; Ling C
Diabetologia; 2017 Jan; 60(1):116-125. PubMed ID: 27796421
[TBL] [Abstract][Full Text] [Related]
13. A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
Koeck T; Olsson AH; Nitert MD; Sharoyko VV; Ladenvall C; Kotova O; Reiling E; Rönn T; Parikh H; Taneera J; Eriksson JG; Metodiev MD; Larsson NG; Balhuizen A; Luthman H; Stančáková A; Kuusisto J; Laakso M; Poulsen P; Vaag A; Groop L; Lyssenko V; Mulder H; Ling C
Cell Metab; 2011 Jan; 13(1):80-91. PubMed ID: 21195351
[TBL] [Abstract][Full Text] [Related]
14. DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets.
Hall E; Dayeh T; Kirkpatrick CL; Wollheim CB; Dekker Nitert M; Ling C
BMC Med Genet; 2013 Jul; 14():76. PubMed ID: 23879380
[TBL] [Abstract][Full Text] [Related]
15. Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.
Olsson AH; Volkov P; Bacos K; Dayeh T; Hall E; Nilsson EA; Ladenvall C; Rönn T; Ling C
PLoS Genet; 2014 Nov; 10(11):e1004735. PubMed ID: 25375650
[TBL] [Abstract][Full Text] [Related]
16. Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes.
Bacos K; Gillberg L; Volkov P; Olsson AH; Hansen T; Pedersen O; Gjesing AP; Eiberg H; Tuomi T; Almgren P; Groop L; Eliasson L; Vaag A; Dayeh T; Ling C
Nat Commun; 2016 Mar; 7():11089. PubMed ID: 27029739
[TBL] [Abstract][Full Text] [Related]
17. Epigenetic regulation of insulin action and secretion - role in the pathogenesis of type 2 diabetes.
Ling C
J Intern Med; 2020 Aug; 288(2):158-167. PubMed ID: 32363639
[TBL] [Abstract][Full Text] [Related]
18. A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.
Peiris H; Duffield MD; Fadista J; Jessup CF; Kashmir V; Genders AJ; McGee SL; Martin AM; Saiedi M; Morton N; Carter R; Cousin MA; Kokotos AC; Oskolkov N; Volkov P; Hough TA; Fisher EM; Tybulewicz VL; Busciglio J; Coskun PE; Becker A; Belichenko PV; Mobley WC; Ryan MT; Chan JY; Laybutt DR; Coates PT; Yang S; Ling C; Groop L; Pritchard MA; Keating DJ
PLoS Genet; 2016 May; 12(5):e1006033. PubMed ID: 27195491
[TBL] [Abstract][Full Text] [Related]
19. Glucolipotoxicity Alters Insulin Secretion via Epigenetic Changes in Human Islets.
Hall E; Jönsson J; Ofori JK; Volkov P; Perfilyev A; Dekker Nitert M; Eliasson L; Ling C; Bacos K
Diabetes; 2019 Oct; 68(10):1965-1974. PubMed ID: 31420409
[TBL] [Abstract][Full Text] [Related]
20. Fat mass and obesity-associated (FTO) gene is essential for insulin secretion and β-cell function: In vitro studies using INS-1 cells and human pancreatic islets.
Taneera J; Khalique A; Abdrabh S; Mohammed AK; Bouzid A; El-Huneidi W; Bustanji Y; Sulaiman N; Albasha S; Saber-Ayad M; Hamad M
Life Sci; 2024 Feb; 339():122421. PubMed ID: 38232799
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
