These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 38103557)

  • 1. MORG1 limits mTORC1 signaling by inhibiting Rag GTPases.
    Abudu YP; Kournoutis A; Brenne HB; Lamark T; Johansen T
    Mol Cell; 2024 Feb; 84(3):552-569.e11. PubMed ID: 38103557
    [TBL] [Abstract][Full Text] [Related]  

  • 2. WDR83/MORG1 inhibits RRAG GTPase-MTORC1 signaling to facilitate basal autophagy.
    Kournoutis A; Lamark T; Johansen T; Abudu YP
    Autophagy; 2024 Jul; 20(7):1687-1688. PubMed ID: 38450633
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
    Oshiro N; Rapley J; Avruch J
    J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.
    Schweitzer LD; Comb WC; Bar-Peled L; Sabatini DM
    Cell Rep; 2015 Sep; 12(9):1445-55. PubMed ID: 26299971
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glutamine and asparagine activate mTORC1 independently of Rag GTPases.
    Meng D; Yang Q; Wang H; Melick CH; Navlani R; Frank AR; Jewell JL
    J Biol Chem; 2020 Mar; 295(10):2890-2899. PubMed ID: 32019866
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids.
    Egri SB; Shen K
    J Biol Chem; 2021 Jul; 297(1):100861. PubMed ID: 34116056
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1).
    Shibutani S; Okazaki H; Iwata H
    J Biol Chem; 2017 Nov; 292(44):18052-18061. PubMed ID: 28808055
    [TBL] [Abstract][Full Text] [Related]  

  • 8. C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.
    Wang M; Wang H; Tao Z; Xia Q; Hao Z; Prehn JHM; Zhen X; Wang G; Ying Z
    Aging Cell; 2020 Apr; 19(4):e13126. PubMed ID: 32100453
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of mTORC1 by the Rag GTPases.
    Lama-Sherpa TD; Jeong MH; Jewell JL
    Biochem Soc Trans; 2023 Apr; 51(2):655-664. PubMed ID: 36929165
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway.
    Lee M; Kim JH; Yoon I; Lee C; Fallahi Sichani M; Kang JS; Kang J; Guo M; Lee KY; Han G; Kim S; Han JM
    Proc Natl Acad Sci U S A; 2018 Jun; 115(23):E5279-E5288. PubMed ID: 29784813
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Purification and biochemical characterization of the Rag GTPase heterodimer.
    Doxsey DD; Shen K
    Methods Enzymol; 2022; 675():131-158. PubMed ID: 36220268
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rag-Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathway.
    Valenstein ML; Lalgudi PV; Gu X; Kedir JF; Taylor MS; Chivukula RR; Sabatini DM
    Proc Natl Acad Sci U S A; 2024 Aug; 121(35):e2322755121. PubMed ID: 39163330
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.
    Shen K; Sabatini DM
    Proc Natl Acad Sci U S A; 2018 Sep; 115(38):9545-9550. PubMed ID: 30181260
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold.
    Lawrence RE; Cho KF; Rappold R; Thrun A; Tofaute M; Kim DJ; Moldavski O; Hurley JH; Zoncu R
    Nat Cell Biol; 2018 Sep; 20(9):1052-1063. PubMed ID: 30061680
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity.
    Li M; Khambu B; Zhang H; Kang JH; Chen X; Chen D; Vollmer L; Liu PQ; Vogt A; Yin XM
    J Biol Chem; 2013 Dec; 288(50):35769-80. PubMed ID: 24174532
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.
    Jung J; Genau HM; Behrends C
    Mol Cell Biol; 2015 Jul; 35(14):2479-94. PubMed ID: 25963655
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p62 is a key regulator of nutrient sensing in the mTORC1 pathway.
    Duran A; Amanchy R; Linares JF; Joshi J; Abu-Baker S; Porollo A; Hansen M; Moscat J; Diaz-Meco MT
    Mol Cell; 2011 Oct; 44(1):134-46. PubMed ID: 21981924
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability.
    Shen K; Choe A; Sabatini DM
    Mol Cell; 2017 Nov; 68(3):552-565.e8. PubMed ID: 29056322
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
    Efeyan A; Zoncu R; Chang S; Gumper I; Snitkin H; Wolfson RL; Kirak O; Sabatini DD; Sabatini DM
    Nature; 2013 Jan; 493(7434):679-83. PubMed ID: 23263183
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nudix-type motif 2 contributes to cancer proliferation through the regulation of Rag GTPase-mediated mammalian target of rapamycin complex 1 localization.
    Kwon O; Kwak D; Ha SH; Jeon H; Park M; Chang Y; Suh PG; Ryu SH
    Cell Signal; 2017 Apr; 32():24-35. PubMed ID: 28089905
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.