These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 38110432)

  • 1. Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma.
    Mohamed MF; Ibrahim NS; Saddiq AA; Abdelhamid IA
    Sci Rep; 2023 Dec; 13(1):22486. PubMed ID: 38110432
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p53-dependent and -independent mechanisms are involved in (E)-1-(2-hydroxyphenyl)-3-(2-methoxynaphthalen-1-yl)prop-2-en-1-one (HMP)-induced apoptosis in HCT116 colon cancer cells.
    Shin SY; Ahn S; Koh D; Lim Y
    Biochem Biophys Res Commun; 2016 Oct; 479(4):913-919. PubMed ID: 27641669
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel [l,2,4]triazolo[3,4-a]isoquinoline chalcones as new chemotherapeutic agents: Block IAP tyrosine kinase domain and induce both intrinsic and extrinsic pathways of apoptosis.
    Mohamed MF; Sroor FM; Ibrahim NS; Salem GS; El-Sayed HH; Mahmoud MM; Wagdy MM; Ahmed AM; Mahmoud AT; Ibrahim SS; Ismail MM; Eldin SM; Saleh FM; Hassaneen HM; Abdelhamid IA
    Invest New Drugs; 2021 Feb; 39(1):98-110. PubMed ID: 32856275
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones.
    Mohamed MF; Hassaneen HM; Abdelhamid IA
    Eur J Med Chem; 2018 Jan; 143():532-541. PubMed ID: 29207336
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer.
    Tantawy MA; Sroor FM; Mohamed MF; El-Naggar ME; Saleh FM; Hassaneen HM; Abdelhamid IA
    Anticancer Agents Med Chem; 2020; 20(1):70-83. PubMed ID: 31696811
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A boronic-chalcone derivative exhibits potent anticancer activity through inhibition of the proteasome.
    Achanta G; Modzelewska A; Feng L; Khan SR; Huang P
    Mol Pharmacol; 2006 Jul; 70(1):426-33. PubMed ID: 16636137
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel p-Functionalized Chromen-4-on-3-yl Chalcones Bearing Astonishing Boronic Acid Moiety as MDM2 Inhibitor: Synthesis, Cytotoxic Evaluation and Simulation Studies.
    Bhatia RK; Singh L; Garg R; Kaur M; Yadav M; Madan J; Kancherla S; Pissurlenkar RRS; Coutinho EC
    Med Chem; 2020; 16(2):212-228. PubMed ID: 31146672
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and Characterization of a New Benzoindole Derivative with Apoptotic Activity Against Colon Cancer Cells.
    Hajiaghaalipour F; Faraj FL; Bagheri E; Ali HM; Abdulla MA; Majid NA
    Curr Pharm Des; 2017; 23(41):6358-6365. PubMed ID: 28325143
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hinokiflavone, as a MDM2 inhibitor, activates p53 signaling pathway to induce apoptosis in human colon cancer HCT116 cells.
    Zhang S; Wang Y; Sun Y; Zhao G; Wang J; Liu L; Liu F; Wang P; Yang J; Xu X
    Biochem Biophys Res Commun; 2022 Feb; 594():93-100. PubMed ID: 35078113
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Attacking the mitochondria of colorectal carcinoma by novel 2-cyanoacrylamides linked to ethyl 1,3-diphenylpyrazole-4-carboxylates moiety as a new trend for chemotherapy.
    Mohamed MF; Saddiq AA; Abdelhamid IA
    Bioorg Chem; 2020 Oct; 103():104195. PubMed ID: 32896741
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting the MDM2-p53 protein-protein interaction with prenylchalcones: Synthesis of a small library and evaluation of potential antitumor activity.
    Brandão P; Loureiro JB; Carvalho S; Hamadou MH; Cravo S; Moreira J; Pereira D; Palmeira A; Pinto M; Saraiva L; Cidade H
    Eur J Med Chem; 2018 Aug; 156():711-721. PubMed ID: 30041135
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA Fragmentation, Cell Cycle Arrest, and Docking Study of Novel Bis Spiro-cyclic 2-oxindole of Pyrimido[4,5-b]quinoline-4,6-dione Derivatives Against Breast Carcinoma.
    Mohamed MF; Abdelmoniem AM; Elwahy AHM; Abdelhamid IA
    Curr Cancer Drug Targets; 2018; 18(4):372-381. PubMed ID: 28669339
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New cell cycle checkpoint pathways regulators with 2-Oxo-indoline scaffold as potential anticancer agents: Design, synthesis, biological activities and in silico studies.
    Abd El-Wahab HAA; Mansour HS; Ali AM; El-Awady R; Aboul-Fadl T
    Bioorg Chem; 2022 Mar; 120():105622. PubMed ID: 35091290
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells.
    Phang CW; Karsani SA; Sethi G; Abd Malek SN
    PLoS One; 2016; 11(2):e0148775. PubMed ID: 26859847
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel Tetrahydro-[1,2,4]triazolo[3,4-
    Darwish MIM; Moustafa AM; Youssef AM; Mansour M; Yousef AI; El Omri A; Shawki HH; Mohamed MF; Hassaneen HM; Abdelhamid IA; Oishi H
    Molecules; 2023 Apr; 28(8):. PubMed ID: 37110575
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthetic antiprotozoal thiazolide drug induced apoptosis in colorectal cancer cells: implications of IL-6/JAK2/STAT3 and p53/caspases-dependent signaling pathways based on molecular docking and in vitro study.
    Tantawy MA; El-Sherbeeny NA; Helmi N; Alazragi R; Salem N; Elaidy SM
    Mol Cell Biochem; 2020 Jun; 469(1-2):143-157. PubMed ID: 32356241
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Spiro-oxindole derivative 5-chloro-4',5'-diphenyl-3'-(4-(2-(piperidin-1-yl) ethoxy) benzoyl) spiro[indoline-3,2'-pyrrolidin]-2-one triggers apoptosis in breast cancer cells via restoration of p53 function.
    Saxena R; Gupta G; Manohar M; Debnath U; Popli P; Prabhakar YS; Konwar R; Kumar S; Kumar A; Dwivedi A
    Int J Biochem Cell Biol; 2016 Jan; 70():105-17. PubMed ID: 26556313
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, Synthesis and Bioactivity Evaluation of Novel Chalcone Derivatives Possessing Tryptophan Moiety with Dual Activities of Anti-Cancer and Partially Restoring the Proliferation of Normal Kidney Cells Pre-Treated with Cisplatin.
    He M; Yu M; Li C; Meng X; Su J; Zhu Y; Yao R
    Anticancer Agents Med Chem; 2022; 22(10):1945-1961. PubMed ID: 34674626
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo.
    Zopf S; Neureiter D; Bouralexis S; Abt T; Glaser KB; Okamoto K; Ganslmayer M; Hahn EG; Herold C; Ocker M
    Int J Oncol; 2007 Dec; 31(6):1391-402. PubMed ID: 17982666
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Apoptosis-induced effects of extract from Artemisia annua Linné by modulating PTEN/p53/PDK1/Akt/ signal pathways through PTEN/p53-independent manner in HCT116 colon cancer cells.
    Kim EJ; Kim GT; Kim BM; Lim EG; Kim SY; Kim YM
    BMC Complement Altern Med; 2017 Apr; 17(1):236. PubMed ID: 28454566
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.