BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 38113256)

  • 1. Somatic mutations of MLL4/COMPASS induce cytoplasmic localization providing molecular insight into cancer prognosis and treatment.
    Zhao Z; Aoi Y; Philips CN; Meghani KA; Gold SR; Yu Y; John LS; Qian J; Zeidner JM; Meeks JJ; Shilatifard A
    Proc Natl Acad Sci U S A; 2023 Dec; 120(52):e2310063120. PubMed ID: 38113256
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.
    Hu D; Gao X; Morgan MA; Herz HM; Smith ER; Shilatifard A
    Mol Cell Biol; 2013 Dec; 33(23):4745-54. PubMed ID: 24081332
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone H3 lysine 4 methyltransferase KMT2D.
    Froimchuk E; Jang Y; Ge K
    Gene; 2017 Sep; 627():337-342. PubMed ID: 28669924
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.
    Wang LH; Aberin MAE; Wu S; Wang SP
    Biochem Soc Trans; 2021 Jun; 49(3):1041-1054. PubMed ID: 34156443
    [TBL] [Abstract][Full Text] [Related]  

  • 5. KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer.
    Alam H; Tang M; Maitituoheti M; Dhar SS; Kumar M; Han CY; Ambati CR; Amin SB; Gu B; Chen TY; Lin YH; Chen J; Muller FL; Putluri N; Flores ER; DeMayo FJ; Baseler L; Rai K; Lee MG
    Cancer Cell; 2020 Apr; 37(4):599-617.e7. PubMed ID: 32243837
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells.
    Cao K; Collings CK; Morgan MA; Marshall SA; Rendleman EJ; Ozark PA; Smith ER; Shilatifard A
    Sci Adv; 2018 Jan; 4(1):eaap8747. PubMed ID: 29404406
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.
    Wang SP; Tang Z; Chen CW; Shimada M; Koche RP; Wang LH; Nakadai T; Chramiec A; Krivtsov AV; Armstrong SA; Roeder RG
    Mol Cell; 2017 Jul; 67(2):308-321.e6. PubMed ID: 28732206
    [TBL] [Abstract][Full Text] [Related]  

  • 8. UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells.
    Kim JH; Sharma A; Dhar SS; Lee SH; Gu B; Chan CH; Lin HK; Lee MG
    Cancer Res; 2014 Mar; 74(6):1705-17. PubMed ID: 24491801
    [TBL] [Abstract][Full Text] [Related]  

  • 9. H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.
    Lee JE; Wang C; Xu S; Cho YW; Wang L; Feng X; Baldridge A; Sartorelli V; Zhuang L; Peng W; Ge K
    Elife; 2013 Dec; 2():e01503. PubMed ID: 24368734
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cancer-epigenetic function of the histone methyltransferase KMT2D and therapeutic opportunities for the treatment of KMT2D-deficient tumors.
    Dhar SS; Lee MG
    Oncotarget; 2021 Jun; 12(13):1296-1308. PubMed ID: 34194626
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.
    Wang C; Lee JE; Lai B; Macfarlan TS; Xu S; Zhuang L; Liu C; Peng W; Ge K
    Proc Natl Acad Sci U S A; 2016 Oct; 113(42):11871-11876. PubMed ID: 27698142
    [TBL] [Abstract][Full Text] [Related]  

  • 12. KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation.
    Guo C; Chen LH; Huang Y; Chang CC; Wang P; Pirozzi CJ; Qin X; Bao X; Greer PK; McLendon RE; Yan H; Keir ST; Bigner DD; He Y
    Oncotarget; 2013 Nov; 4(11):2144-53. PubMed ID: 24240169
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4.
    Rahnamoun H; Hong J; Sun Z; Lee J; Lu H; Lauberth SM
    J Biol Chem; 2018 Aug; 293(34):13234-13246. PubMed ID: 29954944
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).
    Jefri M; Zhang X; Stumpf PS; Zhang L; Peng H; Hettige N; Theroux JF; Aouabed Z; Wilson K; Deshmukh S; Antonyan L; Ni A; Alsuwaidi S; Zhang Y; Jabado N; Garcia BA; Schuppert A; Bjornsson HT; Ernst C
    Hum Mol Genet; 2022 Oct; 31(21):3715-3728. PubMed ID: 35640156
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The histone methyltransferase KMT2D, mutated in Kabuki syndrome patients, is required for neural crest cell formation and migration.
    Schwenty-Lara J; Nehl D; Borchers A
    Hum Mol Genet; 2020 Jan; 29(2):305-319. PubMed ID: 31813957
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4.
    Dhar SS; Lee SH; Kan PY; Voigt P; Ma L; Shi X; Reinberg D; Lee MG
    Genes Dev; 2012 Dec; 26(24):2749-62. PubMed ID: 23249737
    [TBL] [Abstract][Full Text] [Related]  

  • 17. H3K4 Methyltransferase Activity Is Required for MLL4 Protein Stability.
    Jang Y; Wang C; Zhuang L; Liu C; Ge K
    J Mol Biol; 2017 Jun; 429(13):2046-2054. PubMed ID: 28013028
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Research progress of histone 3 methyltransferase MLL4].
    Guo HH; Lu SF; Cai Y; Liu SB; Zhu BM
    Sheng Li Xue Bao; 2019 Aug; 71(4):637-644. PubMed ID: 31440761
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology.
    Shpargel KB; Mangini CL; Xie G; Ge K; Magnuson T
    Development; 2020 Jul; 147(21):. PubMed ID: 32541010
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modus operandi of COMPASS/MLL epigenetic writers in the mammalian genome.
    Bayarsaihan D
    Epigenomics; 2018 Jul; 10(7):861-863. PubMed ID: 29956546
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 10.