BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 38127827)

  • 1. Exceptional Response to MEK Inhibition in a Patient With RAF1-Mutant Myxofibrosarcoma: Case Report and Mechanistic Overview.
    Özgü E; Aydin E; Adibi A; Tokat ÜM; Tutar O; Hu J; Demiray I; Kurzrock R; Demiray M
    JCO Precis Oncol; 2023 Sep; 7():e2300299. PubMed ID: 38127827
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras.
    Jaiswal RK; Moodie SA; Wolfman A; Landreth GE
    Mol Cell Biol; 1994 Oct; 14(10):6944-53. PubMed ID: 7935411
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of BCR- and PKC/Ca(2+)-mediated activation of the Raf1/MEK/MAPK pathway by protein-tyrosine kinase and -tyrosine phosphatase activities.
    Kawauchi K; Lazarus AH; Sanghera JS; Man GL; Pelech SL; Delovitch TL
    Mol Immunol; 1996 Feb; 33(3):287-96. PubMed ID: 8649450
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cardiovascular safety of rapidly accelerated fibrosarcoma B-type and/or mitogen-activated extracellular signal-regulated kinase inhibitors: A mixed approach combining a meta-analysis and a pharmacovigilance disproportionality analysis.
    Dolladille C; Font J; Bejan-Angoulvant T; Zaman K; Sassier M; Ezine E; Stefan A; Plane AF; Legallois D; Milliez P; Parienti JJ; Alexandre J
    Arch Cardiovasc Dis; 2020; 113(6-7):420-432. PubMed ID: 32418884
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human alphaA- and alphaB-crystallins prevent UVA-induced apoptosis through regulation of PKCalpha, RAF/MEK/ERK and AKT signaling pathways.
    Liu JP; Schlosser R; Ma WY; Dong Z; Feng H; Liu L; Huang XQ; Liu Y; Li DW
    Exp Eye Res; 2004 Sep; 79(3):393-403. PubMed ID: 15336502
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells.
    Plattner R; Gupta S; Khosravi-Far R; Sato KY; Perucho M; Der CJ; Stanbridge EJ
    Oncogene; 1999 Mar; 18(10):1807-17. PubMed ID: 10086335
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics.
    Bekele RT; Samant AS; Nassar AH; So J; Garcia EP; Curran CR; Hwang JH; Mayhew DL; Nag A; Thorner AR; Börcsök J; Sztupinszki Z; Pan CX; Bellmunt J; Kwiatkowski DJ; Sonpavde GP; Van Allen EM; Mouw KW
    J Clin Invest; 2021 Nov; 131(22):. PubMed ID: 34554931
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human alphaA- and alphaB-crystallins prevent UVA-induced apoptosis through regulation of PKCalpha, RAF/MEK/ERK and AKT signaling pathways.
    Liu JP; Schlosser R; Ma WY; Dong Z; Feng H; Lui L; Huang XQ; Liu Y; Li DW
    Exp Eye Res; 2004 Dec; 79(6):393-403. PubMed ID: 15669141
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1(L613V) mutation.
    Wu X; Simpson J; Hong JH; Kim KH; Thavarajah NK; Backx PH; Neel BG; Araki T
    J Clin Invest; 2011 Mar; 121(3):1009-25. PubMed ID: 21339642
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.
    Schönwasser DC; Marais RM; Marshall CJ; Parker PJ
    Mol Cell Biol; 1998 Feb; 18(2):790-8. PubMed ID: 9447975
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase.
    Terai K; Matsuda M
    EMBO Rep; 2005 Mar; 6(3):251-5. PubMed ID: 15711535
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity.
    Gardner AM; Vaillancourt RR; Lange-Carter CA; Johnson GL
    Mol Biol Cell; 1994 Feb; 5(2):193-201. PubMed ID: 8019005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway.
    Erhardt P; Schremser EJ; Cooper GM
    Mol Cell Biol; 1999 Aug; 19(8):5308-15. PubMed ID: 10409722
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cadmium induced inflammation and apoptosis of porcine epididymis via activating RAF1/MEK/ERK and NF-κB pathways.
    Zhang Y; Li Y; Zhang J; Qi X; Cui Y; Yin K; Lin H
    Toxicol Appl Pharmacol; 2021 Mar; 415():115449. PubMed ID: 33577919
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The RAS/Raf1/MEK/ERK signaling pathway facilitates VSV-mediated oncolysis: implication for the defective interferon response in cancer cells.
    Noser JA; Mael AA; Sakuma R; Ohmine S; Marcato P; Lee PW; Ikeda Y
    Mol Ther; 2007 Aug; 15(8):1531-6. PubMed ID: 17505473
    [TBL] [Abstract][Full Text] [Related]  

  • 16. miR-4510 blocks hepatocellular carcinoma development through RAF1 targeting and RAS/RAF/MEK/ERK signalling inactivation.
    Ghousein A; Mosca N; Cartier F; Charpentier J; Dupuy JW; Raymond AA; Bioulac-Sage P; Grosset CF
    Liver Int; 2020 Jan; 40(1):240-251. PubMed ID: 31612616
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Radicicol suppresses transformation and restores tropomyosin-2 expression in both ras- and MEK-transformed cells without inhibiting the Raf/MEK/ERK signaling cascade.
    Kim PN; Jonasch E; Mosterman BC; Mier JW; Janssen RA
    Cell Growth Differ; 2001 Nov; 12(11):543-50. PubMed ID: 11714635
    [TBL] [Abstract][Full Text] [Related]  

  • 18. B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP.
    Vaillancourt RR; Gardner AM; Johnson GL
    Mol Cell Biol; 1994 Oct; 14(10):6522-30. PubMed ID: 7935374
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RAF suppression synergizes with MEK inhibition in KRAS mutant cancer cells.
    Lamba S; Russo M; Sun C; Lazzari L; Cancelliere C; Grernrum W; Lieftink C; Bernards R; Di Nicolantonio F; Bardelli A
    Cell Rep; 2014 Sep; 8(5):1475-83. PubMed ID: 25199829
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis.
    Wilhelm SM; Carter C; Tang L; Wilkie D; McNabola A; Rong H; Chen C; Zhang X; Vincent P; McHugh M; Cao Y; Shujath J; Gawlak S; Eveleigh D; Rowley B; Liu L; Adnane L; Lynch M; Auclair D; Taylor I; Gedrich R; Voznesensky A; Riedl B; Post LE; Bollag G; Trail PA
    Cancer Res; 2004 Oct; 64(19):7099-109. PubMed ID: 15466206
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.