160 related articles for article (PubMed ID: 38135129)
1. Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance.
Feng M; Santhanam RK; Xing H; Zhou M; Jia H
Biochem Pharmacol; 2024 Feb; 220():115991. PubMed ID: 38135129
[TBL] [Abstract][Full Text] [Related]
2. A novel triazole, NMK-T-057, induces autophagic cell death in breast cancer cells by inhibiting γ-secretase-mediated activation of Notch signaling.
Das A; Narayanam MK; Paul S; Mukhnerjee P; Ghosh S; Dastidar DG; Chakrabarty S; Ganguli A; Basu B; Pal M; Chatterji U; Banerjee SK; Karmakar P; Kumar D; Chakrabarti G
J Biol Chem; 2019 Apr; 294(17):6733-6750. PubMed ID: 30824542
[TBL] [Abstract][Full Text] [Related]
3. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
Hales EC; Taub JW; Matherly LH
Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
[TBL] [Abstract][Full Text] [Related]
4. Cervical Cancer Cell Growth, Drug Resistance, and Epithelial-Mesenchymal Transition Are Suppressed by y-Secretase Inhibitor RO4929097.
Wang L; Dai G; Yang J; Wu W; Zhang W
Med Sci Monit; 2018 Jun; 24():4046-4053. PubMed ID: 29899322
[TBL] [Abstract][Full Text] [Related]
5. A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor-initiating cells.
Saito N; Fu J; Zheng S; Yao J; Wang S; Liu DD; Yuan Y; Sulman EP; Lang FF; Colman H; Verhaak RG; Yung WK; Koul D
Stem Cells; 2014 Jan; 32(1):301-12. PubMed ID: 24038660
[TBL] [Abstract][Full Text] [Related]
6. Notch Signaling in Breast Cancer: A Role in Drug Resistance.
BeLow M; Osipo C
Cells; 2020 Sep; 9(10):. PubMed ID: 33003540
[TBL] [Abstract][Full Text] [Related]
7. More Insights on the Use of γ-Secretase Inhibitors in Cancer Treatment.
López-Nieva P; González-Sánchez L; Cobos-Fernández MÁ; Córdoba R; Santos J; Fernández-Piqueras J
Oncologist; 2021 Feb; 26(2):e298-e305. PubMed ID: 33191568
[TBL] [Abstract][Full Text] [Related]
8. Unlocking the Secrets of Cancer Stem Cells with γ-Secretase Inhibitors: A Novel Anticancer Strategy.
Ghanbari-Movahed M; Ghanbari-Movahed Z; Momtaz S; Kilpatrick KL; Farzaei MH; Bishayee A
Molecules; 2021 Feb; 26(4):. PubMed ID: 33673088
[TBL] [Abstract][Full Text] [Related]
9. Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells.
Lombardo Y; Faronato M; Filipovic A; Vircillo V; Magnani L; Coombes RC
Breast Cancer Res; 2014 Jun; 16(3):R62. PubMed ID: 24919951
[TBL] [Abstract][Full Text] [Related]
10. Small molecules that inhibit Notch signaling.
De Kloe GE; De Strooper B
Methods Mol Biol; 2014; 1187():311-22. PubMed ID: 25053499
[TBL] [Abstract][Full Text] [Related]
11. Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke.
Arumugam TV; Cheng YL; Choi Y; Choi YH; Yang S; Yun YK; Park JS; Yang DK; Thundyil J; Gelderblom M; Karamyan VT; Tang SC; Chan SL; Magnus T; Sobey CG; Jo DG
Mol Pharmacol; 2011 Jul; 80(1):23-31. PubMed ID: 21450930
[TBL] [Abstract][Full Text] [Related]
12. Cimigenoside functions as a novel γ-secretase inhibitor and inhibits the proliferation or metastasis of human breast cancer cells by γ-secretase/Notch axis.
Jia H; Liu M; Wang X; Jiang Q; Wang S; Santhanam RK; Lv C; Zhao Q; Lu J
Pharmacol Res; 2021 Jul; 169():105686. PubMed ID: 34022397
[TBL] [Abstract][Full Text] [Related]
13. Role of γ-Secretase Inhibitors for the Treatment of Diverse Disease Conditions through Inhibition of Notch Signaling Pathway.
Mondal A; Bose S; Banerjee S; Pal D
Curr Drug Targets; 2021; 22(15):1799-1807. PubMed ID: 33992061
[TBL] [Abstract][Full Text] [Related]
14. Notch Signaling in Breast Tumor Microenvironment as Mediator of Drug Resistance.
Chimento A; D'Amico M; Pezzi V; De Amicis F
Int J Mol Sci; 2022 Jun; 23(11):. PubMed ID: 35682974
[TBL] [Abstract][Full Text] [Related]
15. γ-Secretase-regulated signaling pathways, such as notch signaling, mediate the differentiation of hematopoietic stem cells, development of the immune system, and peripheral immune responses.
Nagase H; Koh CS; Nakayama K
Curr Stem Cell Res Ther; 2011 Jun; 6(2):131-41. PubMed ID: 21190540
[TBL] [Abstract][Full Text] [Related]
16. Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein.
Yang T; Arslanova D; Gu Y; Augelli-Szafran C; Xia W
Mol Brain; 2008 Nov; 1():15. PubMed ID: 18983676
[TBL] [Abstract][Full Text] [Related]
17. Alpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch.
Floyd DH; Kefas B; Seleverstov O; Mykhaylyk O; Dominguez C; Comeau L; Plank C; Purow B
Neuro Oncol; 2012 Oct; 14(10):1215-26. PubMed ID: 22962413
[TBL] [Abstract][Full Text] [Related]
18. gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.
Meng RD; Shelton CC; Li YM; Qin LX; Notterman D; Paty PB; Schwartz GK
Cancer Res; 2009 Jan; 69(2):573-82. PubMed ID: 19147571
[TBL] [Abstract][Full Text] [Related]
19. γ-Secretase inhibitors for breast cancer and hepatocellular carcinoma: From mechanism to treatment.
Jia H; Wang Z; Zhang J; Feng F
Life Sci; 2021 Mar; 268():119007. PubMed ID: 33428878
[TBL] [Abstract][Full Text] [Related]
20. Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase.
Li T; Wen H; Brayton C; Das P; Smithson LA; Fauq A; Fan X; Crain BJ; Price DL; Golde TE; Eberhart CG; Wong PC
J Biol Chem; 2007 Nov; 282(44):32264-73. PubMed ID: 17827153
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]