207 related articles for article (PubMed ID: 38138448)
1. Development of Novel Pyrrole Derivatives and Their Cinnamic Hybrids as Dual COX-2/LOX Inhibitors.
Noti V; Pontiki E; Hadjipavlou-Litina D
Molecules; 2023 Dec; 28(24):. PubMed ID: 38138448
[TBL] [Abstract][Full Text] [Related]
2. Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition.
Ghanim AM; Rezq S; Ibrahim TS; Romero DG; Kothayer H
Eur J Med Chem; 2021 Jul; 219():113457. PubMed ID: 33892270
[TBL] [Abstract][Full Text] [Related]
3. Tailored quinoline hybrids as promising COX-2/15-LOX dual inhibitors endowed with diverse safety profile: Design, synthesis, SAR, and histopathological study.
Hegazy ME; Taher ES; Ghiaty AH; Bayoumi AH
Bioorg Chem; 2024 Apr; 145():107244. PubMed ID: 38428284
[TBL] [Abstract][Full Text] [Related]
4. Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids.
Abdu-Allah HHM; Abdelmoez AAB; Tarazi H; El-Shorbagi AA; El-Awady R
Bioorg Chem; 2020 Jan; 94():103378. PubMed ID: 31677858
[TBL] [Abstract][Full Text] [Related]
5. Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes.
Maghraby MT; Abou-Ghadir OMF; Abdel-Moty SG; Ali AY; Salem OIA
Bioorg Med Chem; 2020 Apr; 28(7):115403. PubMed ID: 32127262
[TBL] [Abstract][Full Text] [Related]
6. Characterization of spirostanol glycosides and furostanol glycosides from anemarrhenae rhizoma as dual targeted inhibitors of 5-lipoxygenase and Cyclooxygenase-2 by employing a combination of affinity ultrafiltration and HPLC/MS.
Xie L; Lee DY; Shang Y; Cao X; Wang S; Liao J; Zhang T; Dai R
Phytomedicine; 2020 Oct; 77():153284. PubMed ID: 32707371
[TBL] [Abstract][Full Text] [Related]
7. Oxaspiro Indiculides from Old Woman Octopus Cistopus indicus as Dual Inhibitors of Inducible Cyclooxygenase and Lipoxygenase.
Kunnappilly Paulose S; Chakraborty K
Chem Biodivers; 2022 Jul; 19(7):e202200277. PubMed ID: 35661399
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX.
Omar YM; Abdu-Allah HHM; Abdel-Moty SG
Bioorg Chem; 2018 Oct; 80():461-471. PubMed ID: 29986191
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core.
Sisa M; Dvorakova M; Temml V; Jarosova V; Vanek T; Landa P
Eur J Med Chem; 2020 Oct; 204():112620. PubMed ID: 32738413
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and biological evaluation of novel 1,2-diaryl-4-substituted-benzylidene-5(4H)-imidazolone derivatives as cytotoxic agents and COX-2/LOX inhibitors.
Lamie PF; Philoppes JN; Rárová L
Arch Pharm (Weinheim); 2018 Apr; 351(3-4):e1700311. PubMed ID: 29400411
[TBL] [Abstract][Full Text] [Related]
11. Synthesis of novel hybrids of pyrazole and coumarin as dual inhibitors of COX-2 and 5-LOX.
Shen FQ; Wang ZC; Wu SY; Ren SZ; Man RJ; Wang BZ; Zhu HL
Bioorg Med Chem Lett; 2017 Aug; 27(16):3653-3660. PubMed ID: 28720504
[TBL] [Abstract][Full Text] [Related]
12. Synthetically-tailored and nature-derived dual COX-2/5-LOX inhibitors: Structural aspects and SAR.
Meshram MA; Bhise UO; Makhal PN; Kaki VR
Eur J Med Chem; 2021 Dec; 225():113804. PubMed ID: 34479036
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX-2/5-LOX inhibitors.
Shaaban MA; Kamal AM; Faggal SI; Farag NA; Aborehab NM; Elsahar AE; Mohamed KO
Arch Pharm (Weinheim); 2020 Nov; 353(11):e2000027. PubMed ID: 32696514
[TBL] [Abstract][Full Text] [Related]
14. Tailoring the substitution pattern of Pyrrolidine-2,5-dione for discovery of new structural template for dual COX/LOX inhibition.
Sadiq A; Mahnashi MH; Alyami BA; Alqahtani YS; Alqarni AO; Rashid U
Bioorg Chem; 2021 Jul; 112():104969. PubMed ID: 34023639
[TBL] [Abstract][Full Text] [Related]
15. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
El-Nagar MKS; Abdu-Allah HHM; Salem OIA; Kafafy AN; Farghaly HSM
Bioorg Chem; 2018 Aug; 78():80-93. PubMed ID: 29550533
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors.
Gedawy EM; Kassab AE; El Kerdawy AM
Eur J Med Chem; 2020 Mar; 189():112066. PubMed ID: 31982653
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity.
Shrivastava SK; Srivastava P; Bandresh R; Tripathi PN; Tripathi A
Bioorg Med Chem; 2017 Aug; 25(16):4424-4432. PubMed ID: 28669741
[TBL] [Abstract][Full Text] [Related]
18. Novel 5,6-diphenyl-1,2,4-triazine-3-thiol derivatives as dual COX-2/5-LOX inhibitors devoid of cardiotoxicity.
Saraf P; Nath Tripathi P; Kumar Tripathi M; Tripathi A; Verma H; Kumar Waiker D; Singh R; Kumar Shrivastava S
Bioorg Chem; 2022 Dec; 129():106147. PubMed ID: 36126607
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
Rao PN; Chen QH; Knaus EE
J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
[TBL] [Abstract][Full Text] [Related]
20. Discovery of novel hybrids of diaryl-1,2,4-triazoles and caffeic acid as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase for cancer therapy.
Cai H; Huang X; Xu S; Shen H; Zhang P; Huang Y; Jiang J; Sun Y; Jiang B; Wu X; Yao H; Xu J
Eur J Med Chem; 2016 Jan; 108():89-103. PubMed ID: 26638042
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
