179 related articles for article (PubMed ID: 38139302)
1. Frentizole, a Nontoxic Immunosuppressive Drug, and Its Analogs Display Antitumor Activity via Tubulin Inhibition.
Ramos S; Vicente-Blázquez A; López-Rubio M; Gallego-Yerga L; Álvarez R; Peláez R
Int J Mol Sci; 2023 Dec; 24(24):. PubMed ID: 38139302
[TBL] [Abstract][Full Text] [Related]
2. Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site.
Ouellette V; Bouzriba C; Chavez Alvarez AC; Hamel-Côté G; Fortin S
Bioorg Med Chem Lett; 2024 Jun; 105():129745. PubMed ID: 38614151
[TBL] [Abstract][Full Text] [Related]
3. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
Romagnoli R; Oliva P; Salvador MK; Manfredini S; Padroni C; Brancale A; Ferla S; Hamel E; Ronca R; Maccarinelli F; Rruga F; Mariotto E; Viola G; Bortolozzi R
Eur J Med Chem; 2021 Mar; 214():113229. PubMed ID: 33550186
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R; Baraldi PG; Carrion MD; Lopez Cara C; Preti D; Fruttarolo F; Pavani MG; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Balzarini J; Hadfield JA; Brancale A; Hamel E
J Med Chem; 2007 May; 50(9):2273-7. PubMed ID: 17419607
[TBL] [Abstract][Full Text] [Related]
5. Novel amino analogs of the trimethoxyphenyl ring in potent colchicine site ligands improve solubility by the masked polar group incorporation (MPGI) strategy.
González M; Ellahioui Y; Gallego L; Vicente-Blázquez A; Álvarez R; Medarde M; Peláez R
Bioorg Chem; 2023 Feb; 131():106282. PubMed ID: 36459777
[TBL] [Abstract][Full Text] [Related]
6. Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity.
Shchegravina ES; Svirshchevskaya EV; Combes S; Allegro D; Barbier P; Gigant B; Varela PF; Gavryushin AE; Kobanova DA; Shchekotikhin AE; Fedorov AY
Eur J Med Chem; 2020 Dec; 207():112724. PubMed ID: 32827941
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
[TBL] [Abstract][Full Text] [Related]
8. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
Eissa IH; Dahab MA; Ibrahim MK; Alsaif NA; Alanazi AZ; Eissa SI; Mehany ABM; Beauchemin AM
Bioorg Chem; 2021 Jul; 112():104965. PubMed ID: 34020238
[TBL] [Abstract][Full Text] [Related]
9. Recent advances in research of colchicine binding site inhibitors and their interaction modes with tubulin.
Sun K; Sun Z; Zhao F; Shan G; Meng Q
Future Med Chem; 2021 May; 13(9):839-858. PubMed ID: 33821673
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
Li G; Wang Y; Li L; Ren Y; Deng X; Liu J; Wang W; Luo M; Liu S; Chen J
Eur J Med Chem; 2020 Sep; 202():112519. PubMed ID: 32650183
[TBL] [Abstract][Full Text] [Related]
11. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
Liu YN; Wang JJ; Ji YT; Zhao GD; Tang LQ; Zhang CM; Guo XL; Liu ZP
J Med Chem; 2016 Jun; 59(11):5341-55. PubMed ID: 27172319
[TBL] [Abstract][Full Text] [Related]
12. Rational design and synthesis of 2-anilinopyridinyl-benzothiazole Schiff bases as antimitotic agents.
Shaik TB; Hussaini SMA; Nayak VL; Sucharitha ML; Malik MS; Kamal A
Bioorg Med Chem Lett; 2017 Jun; 27(11):2549-2558. PubMed ID: 28400235
[TBL] [Abstract][Full Text] [Related]
13. New Combretastatin Analogs as Anticancer Agents: Design, Synthesis, Microtubules Polymerization Inhibition, and Molecular Docking Studies.
Abdul Hussein SA; Razzak Mahmood AA; Tahtamouni LH; Balakit AA; Yaseen YS; Al-Hasani RA
Chem Biodivers; 2023 Apr; 20(4):e202201206. PubMed ID: 36890635
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents.
Prasad B; Lakshma Nayak V; Srikanth PS; Baig MF; Subba Reddy NV; Babu KS; Kamal A
Bioorg Chem; 2019 Mar; 83():535-548. PubMed ID: 30472555
[TBL] [Abstract][Full Text] [Related]
15. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
Cheng B; Zhu G; Meng L; Wu G; Chen Q; Ma S
Eur J Med Chem; 2022 Jan; 228():113930. PubMed ID: 34794817
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
Romagnoli R; Baraldi PG; Sarkar T; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Hsieh HP; Hamel E
J Med Chem; 2008 Mar; 51(5):1464-8. PubMed ID: 18260616
[TBL] [Abstract][Full Text] [Related]
17. Structural insight into SSE15206 in complex with tubulin provides a rational design for pyrazolinethioamides as tubulin polymerization inhibitors.
Ma L; Lei J; Chen H; Huang R; Su T; Feng J; Sun Q
Future Med Chem; 2022 Jun; 14(11):785-794. PubMed ID: 35506429
[No Abstract] [Full Text] [Related]
18. Novel Tetrazole Derivatives Targeting Tubulin Endowed with Antiproliferative Activity against Glioblastoma Cells.
Gallego-Yerga L; Chiliquinga AJ; Peláez R
Int J Mol Sci; 2023 Jul; 24(13):. PubMed ID: 37446273
[TBL] [Abstract][Full Text] [Related]
19. New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure-activity relationships, and molecular modelling.
Vicente-Blázquez A; González M; Medarde M; Mollinedo F; Peláez R
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):2025-2044. PubMed ID: 34514909
[TBL] [Abstract][Full Text] [Related]
20. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
Cui YJ; Ma CC; Zhang CM; Tang LQ; Liu ZP
Eur J Med Chem; 2020 Feb; 187():111968. PubMed ID: 31865012
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]