These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 38142561)

  • 1. Synthesis and evaluation of druglike parameters via in silico techniques for a series of heterocyclic monosquarate-amide derivatives as potential carboxylic acid bioisosteres.
    Long N; Le Gresley A; Wozniak A; Brough S; Wren SP
    Bioorg Med Chem; 2024 Jan; 98():117565. PubMed ID: 38142561
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and functionalization of cyclic sulfonimidamides: a novel chiral heterocyclic carboxylic Acid bioisostere.
    Pemberton N; Graden H; Evertsson E; Bratt E; Lepistö M; Johannesson P; Svensson PH
    ACS Med Chem Lett; 2012 Jul; 3(7):574-8. PubMed ID: 24900513
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Unearthing novel thiazolidinone building blocks as carboxylic acid bioisosteres.
    Scanlon JJ; Wren SP
    Future Med Chem; 2020 Oct; 12(20):1855-1864. PubMed ID: 33012189
    [No Abstract]   [Full Text] [Related]  

  • 4. Oxocarbon Acids and their Derivatives in Biological and Medicinal Chemistry.
    Ratto A; Honek JF
    Curr Med Chem; 2024; 31(10):1172-1213. PubMed ID: 36915986
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Surveying heterocycles as amide bioisosteres within a series of mGlu
    Reed CW; Washecheck JP; Quitlag MC; Jenkins MT; Rodriguez AL; Engers DW; Blobaum AL; Conn PJ; Niswender CM; Lindsley CW
    Bioorg Med Chem Lett; 2019 May; 29(10):1211-1214. PubMed ID: 30910459
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group.
    Lassalas P; Oukoloff K; Makani V; James M; Tran V; Yao Y; Huang L; Vijayendran K; Monti L; Trojanowski JQ; Lee VM; Kozlowski MC; Smith AB; Brunden KR; Ballatore C
    ACS Med Chem Lett; 2017 Aug; 8(8):864-868. PubMed ID: 28835803
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel esters and amides of nonsteroidal antiinflammatory carboxylic acids as antioxidants and antiproliferative agents.
    Hellberg MR; Namil A; Delgado P; David KC; Kessler TL; Graff G; Haggard KS; Nixon JC
    J Med Chem; 1999 Jan; 42(2):267-76. PubMed ID: 9925732
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Probing the orthosteric binding site of GABAA receptors with heterocyclic GABA carboxylic acid bioisosteres.
    Petersen JG; Bergmann R; Krogsgaard-Larsen P; Balle T; Frølund B
    Neurochem Res; 2014 Jun; 39(6):1005-15. PubMed ID: 24362592
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sm(II)-Mediated Electron Transfer to Carboxylic Acid Derivatives: Development of Complexity-Generating Cascades.
    Just-Baringo X; Procter DJ
    Acc Chem Res; 2015 May; 48(5):1263-75. PubMed ID: 25871998
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Facile Conversion of Molecularly Complex (Hetero)aryl Carboxylic Acids into Alkynes for Accelerated SAR Exploration.
    Lutter FH; Jouffroy M
    Chemistry; 2021 Oct; 27(60):14816-14820. PubMed ID: 34460121
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1-(5-Carboxyindazol-1-yl)propan-2-ones as dual inhibitors of cytosolic phospholipase A
    Althaus J; Hake T; Hanekamp W; Lehr M
    J Enzyme Inhib Med Chem; 2016; 31(sup1):131-140. PubMed ID: 27162011
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Theoretical Analysis of Anticancer Cellular Effects of Glycoside Amides.
    Tsanov V; Tsanov H
    Anticancer Agents Med Chem; 2022; 22(6):1171-1200. PubMed ID: 34477528
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacement.
    Frohn M; Liu L; Siegmund AC; Qian W; Amegadzie A; Chen N; Tan H; Hickman D; Wood S; Wen PH; Bartberger MD; Whittington DA; Allen JR; Bourbeau MP
    Bioorg Med Chem Lett; 2020 Jul; 30(14):127240. PubMed ID: 32527542
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Direct Amidation of Carboxylic Acids with Nitroarenes.
    Wang SP; Cheung CW; Ma JA
    J Org Chem; 2019 Nov; 84(21):13922-13934. PubMed ID: 31591886
    [No Abstract]   [Full Text] [Related]  

  • 15. Monomers for preparation of amide-linked RNA: asymmetric synthesis of all four nucleoside 5'-azido 3'-carboxylic acids.
    Rozners E; Liu Y
    J Org Chem; 2005 Nov; 70(24):9841-8. PubMed ID: 16292814
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic acid (EAA-090), a potent N-methyl-D-aspartate antagonist, via the use of 3-cyclobutene-1,2-dione as an achiral alpha-amino acid bioisostere.
    Kinney WA; Abou-Gharbia M; Garrison DT; Schmid J; Kowal DM; Bramlett DR; Miller TL; Tasse RP; Zaleska MM; Moyer JA
    J Med Chem; 1998 Jan; 41(2):236-46. PubMed ID: 9457246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Atomic and molecular properties of nonclassical bioisosteric replacements of the carboxylic acid group.
    Arabi AA
    Future Med Chem; 2020 Jun; 12(12):1111-1120. PubMed ID: 32400198
    [No Abstract]   [Full Text] [Related]  

  • 18. Amide bond cleavage: acceleration due to a 1,3-diaxial interaction with a carboxylic acid.
    Gerschler JJ; Wier KA; Hansen DE
    J Org Chem; 2007 Jan; 72(2):654-7. PubMed ID: 17221991
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparisons of pKa and log P values of some carboxylic and phosphonic acids: synthesis and measurement.
    Franz RD
    AAPS PharmSci; 2001; 3(2):E10. PubMed ID: 11741262
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and antimicrobial evaluation of amide derivatives of benzodifuran-2-carboxylic acid.
    Soni JN; Soman SS
    Eur J Med Chem; 2014 Mar; 75():77-81. PubMed ID: 24530493
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.