BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 38149821)

  • 1. Discovery of Quinolinone Hybrids as Dual Inhibitors of Acetylcholinesterase and Aβ Aggregation for Alzheimer's Disease Therapy.
    Manzoor S; Gabr MT; Nafie MS; Raza MK; Khan A; Nayeem SM; Arafa RK; Hoda N
    ACS Chem Neurosci; 2024 Feb; 15(3):539-559. PubMed ID: 38149821
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual targeting of acetylcholinesterase and tau aggregation: Design, synthesis and evaluation of multifunctional deoxyvasicinone analogues for Alzheimer's disease.
    Manzoor S; Gabr MT; Rasool B; Pal K; Hoda N
    Bioorg Chem; 2021 Nov; 116():105354. PubMed ID: 34562674
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New phosphazine and phosphazide derivatives as multifunctional ligands targeting acetylcholinesterase and β-Amyloid aggregation for treatment of Alzheimer's disease.
    El-Sayed NF; El-Hussieny M; Ewies EF; Fouad MA; Boulos LS
    Bioorg Chem; 2020 Jan; 95():103499. PubMed ID: 31838287
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease.
    Zaręba P; Łątka K; Mazur G; Gryzło B; Pasieka A; Godyń J; Panek D; Skrzypczak-Wiercioch A; Höfner GC; Latacz G; Maj M; Espargaró A; Sabaté R; Jóźwiak K; Wanner KT; Sałat K; Malawska B; Kulig K; Bajda M
    Eur J Med Chem; 2023 Dec; 261():115832. PubMed ID: 37837674
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dual inhibitors of β-amyloid aggregation and acetylcholinesterase as multi-target anti-Alzheimer drug candidates.
    Viayna E; Sabate R; Muñoz-Torrero D
    Curr Top Med Chem; 2013; 13(15):1820-42. PubMed ID: 23931440
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel Molecular Hybrids of
    Sharma P; Tripathi A; Tripathi PN; Singh SS; Singh SP; Shrivastava SK
    ACS Chem Neurosci; 2019 Oct; 10(10):4361-4384. PubMed ID: 31491074
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, Synthesis, and Biological Evaluation of Piperazine and
    Waiker DK; Verma A; Akhilesh ; A GT; Singh N; Roy A; Dilnashin H; Tiwari V; Trigun SK; Singh SP; Krishnamurthy S; Lama P; Davisson VJ; Shrivastava SK
    ACS Chem Neurosci; 2023 Jun; 14(11):2217-2242. PubMed ID: 37216500
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluation of 4-aminoquinoline derivatives with an n-octylamino spacer as potential multi-targeting ligands for the treatment of Alzheimer's disease.
    Matošević A; Opsenica DM; Spasić M; Maraković N; Zandona A; Žunec S; Bartolić M; Kovarik Z; Bosak A
    Chem Biol Interact; 2023 Sep; 382():110620. PubMed ID: 37406982
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Flavanone glycosides inhibit β-site amyloid precursor protein cleaving enzyme 1 and cholinesterase and reduce Aβ aggregation in the amyloidogenic pathway.
    Ali MY; Jannat S; Edraki N; Das S; Chang WK; Kim HC; Park SK; Chang MS
    Chem Biol Interact; 2019 Aug; 309():108707. PubMed ID: 31194956
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of novel hybrids containing clioquinol-1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease.
    Li X; Li T; Zhang P; Li X; Lu L; Sun Y; Zhang B; Allen S; White L; Phillips J; Zhu Z; Yao H; Xu J
    Eur J Med Chem; 2022 Dec; 244():114841. PubMed ID: 36257284
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dual Inhibitors of AChE and BACE-1 for Reducing Aβ in Alzheimer's Disease: From In Silico to In Vivo.
    Stern N; Gacs A; Tátrai E; Flachner B; Hajdú I; Dobi K; Bágyi I; Dormán G; Lőrincz Z; Cseh S; Kígyós A; Tóvári J; Goldblum A
    Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361906
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BACE1 molecular docking and anti-Alzheimer's disease activities of ginsenosides.
    Choi RJ; Roy A; Jung HJ; Ali MY; Min BS; Park CH; Yokozawa T; Fan TP; Choi JS; Jung HA
    J Ethnopharmacol; 2016 Aug; 190():219-30. PubMed ID: 27275774
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel chromanone-dithiocarbamate hybrids as multifunctional AChE inhibitors with β-amyloid anti-aggregation properties for the treatment of Alzheimer's disease.
    Jiang N; Ding J; Liu J; Sun X; Zhang Z; Mo Z; Li X; Yin H; Tang W; Xie SS
    Bioorg Chem; 2019 Aug; 89():103027. PubMed ID: 31176237
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and biological evaluation of ferulic acid based 1,3,4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer's disease.
    Tripathi A; Choubey PK; Sharma P; Seth A; Saraf P; Shrivastava SK
    Bioorg Chem; 2020 Jan; 95():103506. PubMed ID: 31887472
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel deoxyvasicinone and tetrahydro-beta-carboline hybrids as inhibitors of acetylcholinesterase and amyloid beta aggregation.
    Du H; Jiang X; Ma M; Xu H; Liu S; Ma F
    Bioorg Med Chem Lett; 2020 Dec; 30(24):127659. PubMed ID: 33137375
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of Multitarget-Directed Ligands from Piperidine Alkaloid Piperine as a Cap Group for the Management of Alzheimer's Disease.
    Bhanukiran K; Singh SK; Singh R; Kumar A; Hemalatha S
    ACS Chem Neurosci; 2023 Aug; 14(15):2743-2760. PubMed ID: 37433759
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives.
    Chakravarty H; Ju Y; Chen WH; Tam KY
    Drug Dev Res; 2020 Apr; 81(2):242-255. PubMed ID: 31837041
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuroprotective effects of bergenin in Alzheimer's disease: Investigation through molecular docking, in vitro and in vivo studies.
    Barai P; Raval N; Acharya S; Borisa A; Bhatt H; Acharya N
    Behav Brain Res; 2019 Jan; 356():18-40. PubMed ID: 30118774
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics.
    Kwon YE; Park JY; No KT; Shin JH; Lee SK; Eun JS; Yang JH; Shin TY; Kim DK; Chae BS; Leem JY; Kim KH
    Bioorg Med Chem; 2007 Oct; 15(20):6596-607. PubMed ID: 17681794
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New compounds from heterocyclic amines scaffold with multitarget inhibitory activity on Aβ aggregation, AChE, and BACE1 in the Alzheimer disease.
    García Marín ID; Camarillo López RH; Martínez OA; Padilla-Martínez II; Correa-Basurto J; Rosales-Hernández MC
    PLoS One; 2022; 17(6):e0269129. PubMed ID: 35657793
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.