BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 38149908)

  • 1. Functional analyses of Toxoplasma gondii dihydroorotase reveal a promising anti-parasitic target.
    Pan M; Ge CC; Niu SZ; Duan YY; Fan YM; Jin QW; Chen X; Tao JP; Huang SY
    FASEB J; 2024 Jan; 38(1):e23397. PubMed ID: 38149908
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enzymes of the de novo pyrimidine biosynthetic pathway in Toxoplasma gondii.
    Asai T; O'Sullivan WJ; Kobayashi M; Gero AM; Yokogawa M; Tatibana M
    Mol Biochem Parasitol; 1983 Feb; 7(2):89-100. PubMed ID: 6855812
    [TBL] [Abstract][Full Text] [Related]  

  • 3. De novo pyrimidine biosynthesis is required for virulence of Toxoplasma gondii.
    Fox BA; Bzik DJ
    Nature; 2002 Feb; 415(6874):926-9. PubMed ID: 11859373
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic identification of essential indels and domains in carbamoyl phosphate synthetase II of Toxoplasma gondii.
    Fox BA; Ristuccia JG; Bzik DJ
    Int J Parasitol; 2009 Apr; 39(5):533-9. PubMed ID: 18992249
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular biology and biochemistry of malarial parasite pyrimidine biosynthetic pathway.
    Krungkrai J; Prapunwatana P; Wichitkul C; Reungprapavut S; Krungkrai SR; Horii T
    Southeast Asian J Trop Med Public Health; 2003; 34 Suppl 2():32-43. PubMed ID: 19230569
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pyrimidine salvage pathways in Toxoplasma gondii.
    Iltzsch MH
    J Eukaryot Microbiol; 1993; 40(1):24-8. PubMed ID: 8457800
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Avirulent uracil auxotrophs based on disruption of orotidine-5'-monophosphate decarboxylase elicit protective immunity to Toxoplasma gondii.
    Fox BA; Bzik DJ
    Infect Immun; 2010 Sep; 78(9):3744-52. PubMed ID: 20605980
    [TBL] [Abstract][Full Text] [Related]  

  • 8. De novo pyrimidine biosynthesis in the oomycete plant pathogen Phytophthora infestans.
    García-Bayona L; Garavito MF; Lozano GL; Vasquez JJ; Myers K; Fry WE; Bernal A; Zimmermann BH; Restrepo S
    Gene; 2014 Mar; 537(2):312-21. PubMed ID: 24361203
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The dihydroorotase domain of the multifunctional protein CAD. Subunit structure, zinc content, and kinetics.
    Kelly RE; Mally MI; Evans DR
    J Biol Chem; 1986 May; 261(13):6073-83. PubMed ID: 2871022
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyrimidine biosynthesis in parasitic protozoa: purification of a monofunctional dihydroorotase from Plasmodium berghei and Crithidia fasciculata.
    Krungkrai J; Cerami A; Henderson GB
    Biochemistry; 1990 Jul; 29(26):6270-5. PubMed ID: 1976382
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of 6-azauridine on de novo pyrimidine biosynthesis in cultured Ehrlich ascites cells. Orotate inhibition of dihydroorotase and dihydroorotate dehydrogenase.
    Chen JJ; Jones ME
    J Biol Chem; 1979 Jun; 254(11):4908-14. PubMed ID: 35542
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae.
    Lipowska J; Miks CD; Kwon K; Shuvalova L; Zheng H; Lewiński K; Cooper DR; Shabalin IG; Minor W
    Int J Biol Macromol; 2019 Sep; 136():1176-1187. PubMed ID: 31207330
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pyrimidine Pathway-Dependent and -Independent Functions of the Toxoplasma gondii Mitochondrial Dihydroorotate Dehydrogenase.
    Hortua Triana MA; Cajiao Herrera D; Zimmermann BH; Fox BA; Bzik DJ
    Infect Immun; 2016 Oct; 84(10):2974-81. PubMed ID: 27481247
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enzymes of de novo pyrimidine biosynthesis in Babesia rodhaini.
    Holland JW; Gero AM; O'Sullivan WJ
    J Protozool; 1983 Feb; 30(1):36-40. PubMed ID: 6134826
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intersubunit communication in the dihydroorotase-aspartate transcarbamoylase complex of Aquifex aeolicus.
    Evans HG; Fernando R; Vaishnav A; Kotichukkala M; Heyl D; Hachem F; Brunzelle JS; Edwards BF; Evans DR
    Protein Sci; 2014 Jan; 23(1):100-9. PubMed ID: 24353170
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytotoxic effects of inhibitors of de novo pyrimidine biosynthesis upon Plasmodium falciparum.
    Seymour KK; Lyons SD; Phillips L; Rieckmann KH; Christopherson RI
    Biochemistry; 1994 May; 33(17):5268-74. PubMed ID: 7909690
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dihydroorotase from the hyperthermophile Aquifex aeolicus is activated by stoichiometric association with aspartate transcarbamoylase and forms a one-pot reactor for pyrimidine biosynthesis.
    Zhang P; Martin PD; Purcarea C; Vaishnav A; Brunzelle JS; Fernando R; Guy-Evans HI; Evans DR; Edwards BF
    Biochemistry; 2009 Feb; 48(4):766-78. PubMed ID: 19128030
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Animal Models for Toxoplasma gondii Infection.
    S Subauste C; Hubal A
    Curr Protoc; 2023 Sep; 3(9):e871. PubMed ID: 37695167
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism of the dihydroorotase reaction.
    Porter TN; Li Y; Raushel FM
    Biochemistry; 2004 Dec; 43(51):16285-92. PubMed ID: 15610022
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Toxoplasma gondii lacks the enzymes required for de novo arginine biosynthesis and arginine starvation triggers cyst formation.
    Fox BA; Gigley JP; Bzik DJ
    Int J Parasitol; 2004 Mar; 34(3):323-31. PubMed ID: 15003493
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.