These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity. Long E; Yin J; Funderburk KM; Xu M; Feng J; Kane A; Zhang T; Myers T; Golden A; Thakur R; Kong H; Jessop L; Kim EY; Jones K; Chari R; Machiela MJ; Yu K; ; Iles MM; Landi MT; Law MH; Chanock SJ; Brown KM; Choi J Am J Hum Genet; 2022 Dec; 109(12):2210-2229. PubMed ID: 36423637 [TBL] [Abstract][Full Text] [Related]
4. Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays. Castaldi PJ; Guo F; Qiao D; Du F; Naing ZZC; Li Y; Pham B; Mikkelsen TS; Cho MH; Silverman EK; Zhou X Am J Respir Crit Care Med; 2019 Jan; 199(1):52-61. PubMed ID: 30079747 [TBL] [Abstract][Full Text] [Related]
5. On the identification of potential regulatory variants within genome wide association candidate SNP sets. Chen CY; Chang IS; Hsiung CA; Wasserman WW BMC Med Genomics; 2014 Jun; 7():34. PubMed ID: 24920305 [TBL] [Abstract][Full Text] [Related]
7. Mapping the functional impact of non-coding regulatory elements in primary T cells through single-cell CRISPR screens. Alda-Catalinas C; Ibarra-Soria X; Flouri C; Gordillo JE; Cousminer D; Hutchinson A; Sun B; Pembroke W; Ullrich S; Krejci A; Cortes A; Acevedo A; Malla S; Fishwick C; Drewes G; Rapiteanu R Genome Biol; 2024 Feb; 25(1):42. PubMed ID: 38308274 [TBL] [Abstract][Full Text] [Related]
8. Identification of breast cancer associated variants that modulate transcription factor binding. Liu Y; Walavalkar NM; Dozmorov MG; Rich SS; Civelek M; Guertin MJ PLoS Genet; 2017 Sep; 13(9):e1006761. PubMed ID: 28957321 [TBL] [Abstract][Full Text] [Related]
9. Decoding Non-coding Variants: Recent Approaches to Studying Their Role in Gene Regulation and Human Diseases. Peña-Martínez EG; Rodríguez-Martínez JA Front Biosci (Schol Ed); 2024 Mar; 16(1):4. PubMed ID: 38538340 [TBL] [Abstract][Full Text] [Related]
10. Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens. Morris JA; Caragine C; Daniloski Z; Domingo J; Barry T; Lu L; Davis K; Ziosi M; Glinos DA; Hao S; Mimitou EP; Smibert P; Roeder K; Katsevich E; Lappalainen T; Sanjana NE Science; 2023 May; 380(6646):eadh7699. PubMed ID: 37141313 [TBL] [Abstract][Full Text] [Related]
11. Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease. Selvarajan I; Toropainen A; Garske KM; López Rodríguez M; Ko A; Miao Z; Kaminska D; Õunap K; Örd T; Ravindran A; Liu OH; Moreau PR; Jawahar Deen A; Männistö V; Pan C; Levonen AL; Lusis AJ; Heikkinen S; Romanoski CE; Pihlajamäki J; Pajukanta P; Kaikkonen MU Am J Hum Genet; 2021 Mar; 108(3):411-430. PubMed ID: 33626337 [TBL] [Abstract][Full Text] [Related]
12. Functional genomics elucidates regulatory mechanisms of Parkinson's disease-associated variants. Chen R; Liu J; Li S; Li X; Huo Y; Yao YG; Xiao X; Li M; Luo XJ BMC Med; 2022 Feb; 20(1):68. PubMed ID: 35168626 [TBL] [Abstract][Full Text] [Related]
13. Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants. Chen R; Yang Z; Liu J; Cai X; Huo Y; Zhang Z; Li M; Chang H; Luo XJ Genome Med; 2022 May; 14(1):53. PubMed ID: 35590387 [TBL] [Abstract][Full Text] [Related]
14. Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding? Moyerbrailean GA; Kalita CA; Harvey CT; Wen X; Luca F; Pique-Regi R PLoS Genet; 2016 Feb; 12(2):e1005875. PubMed ID: 26901046 [TBL] [Abstract][Full Text] [Related]
15. GERV: a statistical method for generative evaluation of regulatory variants for transcription factor binding. Zeng H; Hashimoto T; Kang DD; Gifford DK Bioinformatics; 2016 Feb; 32(4):490-6. PubMed ID: 26476779 [TBL] [Abstract][Full Text] [Related]
17. Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain. Handel AE; Gallone G; Zameel Cader M; Ponting CP Hum Mol Genet; 2017 Jan; 26(1):79-89. PubMed ID: 27798116 [TBL] [Abstract][Full Text] [Related]
18. Cannon ME; Duan Q; Wu Y; Zeynalzadeh M; Xu Z; Kangas AJ; Soininen P; Ala-Korpela M; Civelek M; Lusis AJ; Kuusisto J; Collins FS; Boehnke M; Tang H; Laakso M; Li Y; Mohlke KL G3 (Bethesda); 2017 Sep; 7(9):3217-3227. PubMed ID: 28754724 [TBL] [Abstract][Full Text] [Related]
19. Focus on your locus with a massively parallel reporter assay. McAfee JC; Bell JL; Krupa O; Matoba N; Stein JL; Won H J Neurodev Disord; 2022 Sep; 14(1):50. PubMed ID: 36085003 [TBL] [Abstract][Full Text] [Related]
20. CRISPR screens identify gene targets at breast cancer risk loci. Tuano NK; Beesley J; Manning M; Shi W; Perlaza-Jimenez L; Malaver-Ortega LF; Paynter JM; Black D; Civitarese A; McCue K; Hatzipantelis A; Hillman K; Kaufmann S; Sivakumaran H; Polo JM; Reddel RR; Band V; French JD; Edwards SL; Powell DR; Chenevix-Trench G; Rosenbluh J Genome Biol; 2023 Mar; 24(1):59. PubMed ID: 36991492 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]