239 related articles for article (PubMed ID: 38170217)
1. Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.
Zhu Y; Burg T; Neyrinck K; Vervliet T; Nami F; Vervoort E; Ahuja K; Sassano ML; Chai YC; Tharkeshwar AK; De Smedt J; Hu H; Bultynck G; Agostinis P; Swinnen JV; Van Den Bosch L; da Costa RFM; Verfaillie C
Acta Neuropathol; 2024 Jan; 147(1):6. PubMed ID: 38170217
[TBL] [Abstract][Full Text] [Related]
2. Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.
Akiyama T; Suzuki N; Ishikawa M; Fujimori K; Sone T; Kawada J; Funayama R; Fujishima F; Mitsuzawa S; Ikeda K; Ono H; Shijo T; Osana S; Shirota M; Nakagawa T; Kitajima Y; Nishiyama A; Izumi R; Morimoto S; Okada Y; Kamei T; Nishida M; Nogami M; Kaneda S; Ikeuchi Y; Mitsuhashi H; Nakayama K; Fujii T; Warita H; Okano H; Aoki M
EBioMedicine; 2019 Jul; 45():362-378. PubMed ID: 31262712
[TBL] [Abstract][Full Text] [Related]
3. HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.
Guo W; Naujock M; Fumagalli L; Vandoorne T; Baatsen P; Boon R; Ordovás L; Patel A; Welters M; Vanwelden T; Geens N; Tricot T; Benoy V; Steyaert J; Lefebvre-Omar C; Boesmans W; Jarpe M; Sterneckert J; Wegner F; Petri S; Bohl D; Vanden Berghe P; Robberecht W; Van Damme P; Verfaillie C; Van Den Bosch L
Nat Commun; 2017 Oct; 8(1):861. PubMed ID: 29021520
[TBL] [Abstract][Full Text] [Related]
4. FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration.
Szewczyk B; Günther R; Japtok J; Frech MJ; Naumann M; Lee HO; Hermann A
Cell Rep; 2023 Feb; 42(2):112025. PubMed ID: 36696267
[TBL] [Abstract][Full Text] [Related]
5. lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons.
Provasek VE; Kodavati M; Guo W; Wang H; Boldogh I; Van Den Bosch L; Britz G; Hegde ML
Cells; 2023 Oct; 12(20):. PubMed ID: 37887305
[TBL] [Abstract][Full Text] [Related]
6. The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation.
Liu X; Chen J; Liu W; Li X; Chen Q; Liu T; Gao S; Deng M
Neurogenetics; 2015 Jul; 16(3):223-31. PubMed ID: 25912081
[TBL] [Abstract][Full Text] [Related]
7. IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS-associated amyotrophic lateral sclerosis.
Assoni AF; Guerrero EN; Wardenaar R; Oliveira D; Bakker PL; Alves LM; Carvalho VM; Okamoto OK; Zatz M; Foijer F
Brain Pathol; 2024 Jan; 34(1):e13206. PubMed ID: 37582053
[TBL] [Abstract][Full Text] [Related]
8. Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.
Bursch F; Kalmbach N; Naujock M; Staege S; Eggenschwiler R; Abo-Rady M; Japtok J; Guo W; Hensel N; Reinhardt P; Boeckers TM; Cantz T; Sterneckert J; Van Den Bosch L; Hermann A; Petri S; Wegner F
Hum Mol Genet; 2019 Sep; 28(17):2835-2850. PubMed ID: 31108504
[TBL] [Abstract][Full Text] [Related]
9. Differentiation but not ALS mutations in FUS rewires motor neuron metabolism.
Vandoorne T; Veys K; Guo W; Sicart A; Vints K; Swijsen A; Moisse M; Eelen G; Gounko NV; Fumagalli L; Fazal R; Germeys C; Quaegebeur A; Fendt SM; Carmeliet P; Verfaillie C; Van Damme P; Ghesquière B; De Bock K; Van Den Bosch L
Nat Commun; 2019 Sep; 10(1):4147. PubMed ID: 31515480
[TBL] [Abstract][Full Text] [Related]
10. ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons.
Lenzi J; De Santis R; de Turris V; Morlando M; Laneve P; Calvo A; Caliendo V; Chiò A; Rosa A; Bozzoni I
Dis Model Mech; 2015 Jul; 8(7):755-66. PubMed ID: 26035390
[TBL] [Abstract][Full Text] [Related]
11. Mutations in FUS lead to synaptic dysregulation in ALS-iPSC derived neurons.
Shum C; Hedges EC; Allison J; Lee YB; Arias N; Cocks G; Chandran S; Ruepp MD; Shaw CE; Nishimura AL
Stem Cell Reports; 2024 Feb; 19(2):187-195. PubMed ID: 38242131
[TBL] [Abstract][Full Text] [Related]
12. ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.
Groen EJ; Fumoto K; Blokhuis AM; Engelen-Lee J; Zhou Y; van den Heuvel DM; Koppers M; van Diggelen F; van Heest J; Demmers JA; Kirby J; Shaw PJ; Aronica E; Spliet WG; Veldink JH; van den Berg LH; Pasterkamp RJ
Hum Mol Genet; 2013 Sep; 22(18):3690-704. PubMed ID: 23681068
[TBL] [Abstract][Full Text] [Related]
13. Generation of two induced pluripotent stem cell lines with heterozygous and homozygous amyotrophic lateral sclerosis-causing mutation P525L (c.1574C > T) in FUS gene.
Akter M; Cui H; Abir Hosain M; Ding B
Stem Cell Res; 2023 Jun; 69():103103. PubMed ID: 37116345
[TBL] [Abstract][Full Text] [Related]
14. Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition.
Pelaez MC; Desmeules A; Gelon PA; Glasson B; Marcadet L; Rodgers A; Phaneuf D; Pozzi S; Dutchak PA; Julien JP; Sephton CF
Acta Neuropathol Commun; 2023 Nov; 11(1):182. PubMed ID: 37974279
[TBL] [Abstract][Full Text] [Related]
15. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.
Naumann M; Pal A; Goswami A; Lojewski X; Japtok J; Vehlow A; Naujock M; Günther R; Jin M; Stanslowsky N; Reinhardt P; Sterneckert J; Frickenhaus M; Pan-Montojo F; Storkebaum E; Poser I; Freischmidt A; Weishaupt JH; Holzmann K; Troost D; Ludolph AC; Boeckers TM; Liebau S; Petri S; Cordes N; Hyman AA; Wegner F; Grill SW; Weis J; Storch A; Hermann A
Nat Commun; 2018 Jan; 9(1):335. PubMed ID: 29362359
[TBL] [Abstract][Full Text] [Related]
16. Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.
Ichiyanagi N; Fujimori K; Yano M; Ishihara-Fujisaki C; Sone T; Akiyama T; Okada Y; Akamatsu W; Matsumoto T; Ishikawa M; Nishimoto Y; Ishihara Y; Sakuma T; Yamamoto T; Tsuiji H; Suzuki N; Warita H; Aoki M; Okano H
Stem Cell Reports; 2016 Apr; 6(4):496-510. PubMed ID: 26997647
[TBL] [Abstract][Full Text] [Related]
17. Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis.
Farg MA; Soo KY; Warraich ST; Sundaramoorthy V; Blair IP; Atkin JD
Hum Mol Genet; 2013 Feb; 22(4):717-28. PubMed ID: 23172909
[TBL] [Abstract][Full Text] [Related]
18. 4-Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient-Derived Induced Pluripotent Stem Cells.
Naujock M; Stanslowsky N; Bufler S; Naumann M; Reinhardt P; Sterneckert J; Kefalakes E; Kassebaum C; Bursch F; Lojewski X; Storch A; Frickenhaus M; Boeckers TM; Putz S; Demestre M; Liebau S; Klingenstein M; Ludolph AC; Dengler R; Kim KS; Hermann A; Wegner F; Petri S
Stem Cells; 2016 Jun; 34(6):1563-75. PubMed ID: 26946488
[TBL] [Abstract][Full Text] [Related]
19. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
[TBL] [Abstract][Full Text] [Related]
20. Homozygous ALS-linked FUS P525L mutations cell- autonomously perturb transcriptome profile and chemoreceptor signaling in human iPSC microglia.
Kerk SY; Bai Y; Smith J; Lalgudi P; Hunt C; Kuno J; Nuara J; Yang T; Lanza K; Chan N; Coppola A; Tang Q; Espert J; Jones H; Fannell C; Zambrowicz B; Chiao E
Stem Cell Reports; 2022 Mar; 17(3):678-692. PubMed ID: 35120624
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
