124 related articles for article (PubMed ID: 38175211)
1. Role of ATP Hydrolysis and Product Release in the Translocation Mechanism of SARS-CoV-2 NSP13.
Lawal MM; Roy P; McCullagh M
J Phys Chem B; 2024 Jan; 128(2):492-503. PubMed ID: 38175211
[TBL] [Abstract][Full Text] [Related]
2. The Role of ATP Hydrolysis and Product Release in the Translocation Mechanism of SARS-CoV-2 NSP13.
Lawal MM; Roy P; McCullagh M
bioRxiv; 2023 Sep; ():. PubMed ID: 37808802
[TBL] [Abstract][Full Text] [Related]
3. Role of ATP in the RNA Translocation Mechanism of SARS-CoV-2 NSP13 Helicase.
Weber R; McCullagh M
J Phys Chem B; 2021 Aug; 125(31):8787-8796. PubMed ID: 34328740
[TBL] [Abstract][Full Text] [Related]
4. Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase.
Newman JA; Douangamath A; Yadzani S; Yosaatmadja Y; Aimon A; Brandão-Neto J; Dunnett L; Gorrie-Stone T; Skyner R; Fearon D; Schapira M; von Delft F; Gileadi O
Nat Commun; 2021 Aug; 12(1):4848. PubMed ID: 34381037
[TBL] [Abstract][Full Text] [Related]
5. Biochemical analysis of SARS-CoV-2 Nsp13 helicase implicated in COVID-19 and factors that regulate its catalytic functions.
Sommers JA; Loftus LN; Jones MP; Lee RA; Haren CE; Dumm AJ; Brosh RM
J Biol Chem; 2023 Mar; 299(3):102980. PubMed ID: 36739951
[TBL] [Abstract][Full Text] [Related]
6. The stalk domain of SARS-CoV-2 NSP13 is essential for its helicase activity.
Yue K; Yao B; Shi Y; Yang Y; Qian Z; Ci Y; Shi L
Biochem Biophys Res Commun; 2022 Apr; 601():129-136. PubMed ID: 35245742
[TBL] [Abstract][Full Text] [Related]
7. Mapping major SARS-CoV-2 drug targets and assessment of druggability using computational fragment screening: Identification of an allosteric small-molecule binding site on the Nsp13 helicase.
Freidel MR; Armen RS
PLoS One; 2021; 16(2):e0246181. PubMed ID: 33596235
[TBL] [Abstract][Full Text] [Related]
8. Discovery of COVID-19 Inhibitors Targeting the SARS-CoV-2 Nsp13 Helicase.
White MA; Lin W; Cheng X
J Phys Chem Lett; 2020 Nov; 11(21):9144-9151. PubMed ID: 33052685
[TBL] [Abstract][Full Text] [Related]
9. SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts.
Shu T; Huang M; Wu D; Ren Y; Zhang X; Han Y; Mu J; Wang R; Qiu Y; Zhang DY; Zhou X
Virol Sin; 2020 Jun; 35(3):321-329. PubMed ID: 32500504
[TBL] [Abstract][Full Text] [Related]
10. Motif V regulates energy transduction between the flavivirus NS3 ATPase and RNA-binding cleft.
Du Pont KE; Davidson RB; McCullagh M; Geiss BJ
J Biol Chem; 2020 Feb; 295(6):1551-1564. PubMed ID: 31914411
[TBL] [Abstract][Full Text] [Related]
11. Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Chen J; Wang Q; Malone B; Llewellyn E; Pechersky Y; Maruthi K; Eng ET; Perry JK; Campbell EA; Shaw DE; Darst SA
Nat Struct Mol Biol; 2022 Mar; 29(3):250-260. PubMed ID: 35260847
[TBL] [Abstract][Full Text] [Related]
12. A high ATP concentration enhances the cooperative translocation of the SARS coronavirus helicase nsP13 in the unwinding of duplex RNA.
Jang KJ; Jeong S; Kang DY; Sp N; Yang YM; Kim DE
Sci Rep; 2020 Mar; 10(1):4481. PubMed ID: 32161317
[TBL] [Abstract][Full Text] [Related]
13. Architecture of a SARS-CoV-2 mini replication and transcription complex.
Yan L; Zhang Y; Ge J; Zheng L; Gao Y; Wang T; Jia Z; Wang H; Huang Y; Li M; Wang Q; Rao Z; Lou Z
Nat Commun; 2020 Nov; 11(1):5874. PubMed ID: 33208736
[TBL] [Abstract][Full Text] [Related]
14. Evaluation of the potency of FDA-approved drugs on wild type and mutant SARS-CoV-2 helicase (Nsp13).
Ugurel OM; Mutlu O; Sariyer E; Kocer S; Ugurel E; Inci TG; Ata O; Turgut-Balik D
Int J Biol Macromol; 2020 Nov; 163():1687-1696. PubMed ID: 32980406
[TBL] [Abstract][Full Text] [Related]
15. A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance.
Grimes SL; Choi YJ; Banerjee A; Small G; Anderson-Daniels J; Gribble J; Pruijssers AJ; Agostini ML; Abu-Shmais A; Lu X; Darst SA; Campbell E; Denison MR
mBio; 2023 Aug; 14(4):e0106023. PubMed ID: 37338298
[TBL] [Abstract][Full Text] [Related]
16. Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex.
Chen J; Malone B; Llewellyn E; Grasso M; Shelton PMM; Olinares PDB; Maruthi K; Eng ET; Vatandaslar H; Chait BT; Kapoor TM; Darst SA; Campbell EA
Cell; 2020 Sep; 182(6):1560-1573.e13. PubMed ID: 32783916
[TBL] [Abstract][Full Text] [Related]
17. ATP dependent NS3 helicase interaction with RNA: insights from molecular simulations.
Pérez-Villa A; Darvas M; Bussi G
Nucleic Acids Res; 2015 Oct; 43(18):8725-34. PubMed ID: 26358809
[TBL] [Abstract][Full Text] [Related]
18. In Silico Binding of 2-Aminocyclobutanones to SARS-CoV-2 Nsp13 Helicase and Demonstration of Antiviral Activity.
Mohammad TSH; Gupta Y; Reidl CT; Nicolaescu V; Gula H; Durvasula R; Kempaiah P; Becker DP
Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982188
[TBL] [Abstract][Full Text] [Related]
19. The PKA-CREB1 axis regulates coronavirus proliferation by viral helicase nsp13 association.
Zheng T; Shen B; Bai Y; Li E; Zhang X; Hu Y; Gao T; Dong Q; Zhu L; Jin R; Shi H; Liu H; Gao Y; Liu X; Cao C
J Virol; 2024 Apr; 98(4):e0156523. PubMed ID: 38445884
[TBL] [Abstract][Full Text] [Related]
20. Activity and inhibition of the SARS-CoV-2 Omicron nsp13 R392C variant using RNA duplex unwinding assays.
Inniss NL; Rzhetskaya M; Ling-Hu T; Lorenzo-Redondo R; Bachta KE; Satchell KJF; Hultquist JF
SLAS Discov; 2024 Apr; 29(3):100145. PubMed ID: 38301954
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
