122 related articles for article (PubMed ID: 38176950)
1. Icariin Inhibits Overexpression and Aggregation of α-Synuclein in A53T α-Synuclein Transgenic Mice by Regulating Parkin and PLK2.
Ma D; Shen C; Zhang X; Zhang L; Li L
J Integr Neurosci; 2023 Nov; 22(6):166. PubMed ID: 38176950
[TBL] [Abstract][Full Text] [Related]
2. Icariin reduces α-synuclein over-expression by promoting α-synuclein degradation.
Zhang L; Shen C; Chu J; Liu Y; Li Y; Zhang L; Li L
Age (Dordr); 2015 Aug; 37(4):9811. PubMed ID: 26169945
[TBL] [Abstract][Full Text] [Related]
3. Neuroprotective effects of extract of Acanthopanax senticosus harms on SH-SY5Y cells overexpressing wild-type or A53T mutant α-synuclein.
Li XZ; Zhang SN; Wang KX; Liu HY; Yang ZM; Liu SM; Lu F
Phytomedicine; 2014 Apr; 21(5):704-11. PubMed ID: 24252343
[TBL] [Abstract][Full Text] [Related]
4. Caffeic acid reduces A53T α-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease.
Zhang Y; Wu Q; Zhang L; Wang Q; Yang Z; Liu J; Feng L
Pharmacol Res; 2019 Dec; 150():104538. PubMed ID: 31707034
[TBL] [Abstract][Full Text] [Related]
5. In vivo modulation of polo-like kinases supports a key role for PLK2 in Ser129 α-synuclein phosphorylation in mouse brain.
Bergeron M; Motter R; Tanaka P; Fauss D; Babcock M; Chiou SS; Nelson S; San Pablo F; Anderson JP
Neuroscience; 2014 Jan; 256():72-82. PubMed ID: 24128992
[TBL] [Abstract][Full Text] [Related]
6. Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy.
von Coelln R; Thomas B; Andrabi SA; Lim KL; Savitt JM; Saffary R; Stirling W; Bruno K; Hess EJ; Lee MK; Dawson VL; Dawson TM
J Neurosci; 2006 Apr; 26(14):3685-96. PubMed ID: 16597723
[TBL] [Abstract][Full Text] [Related]
7. Roflupram attenuates α-synuclein-induced cytotoxicity and promotes the mitochondrial translocation of Parkin in SH-SY5Y cells overexpressing A53T mutant α-synuclein.
Zhong J; Li M; Xu J; Dong W; Qin Y; Qiu S; Li X; Wang H
Toxicol Appl Pharmacol; 2022 Feb; 436():115859. PubMed ID: 34990728
[TBL] [Abstract][Full Text] [Related]
8. Chronic mild stress accelerates the progression of Parkinson's disease in A53T α-synuclein transgenic mice.
Wu Q; Yang X; Zhang Y; Zhang L; Feng L
Exp Neurol; 2016 Nov; 285(Pt A):61-71. PubMed ID: 27637804
[TBL] [Abstract][Full Text] [Related]
9. Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models.
Zhu Q; Zhuang XX; Chen JY; Yuan NN; Chen Y; Cai CZ; Tan JQ; Su HX; Lu JH
Phytomedicine; 2021 Jul; 87():153578. PubMed ID: 34038839
[TBL] [Abstract][Full Text] [Related]
10. α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation.
Chen JY; Zhu Q; Cai CZ; Luo HB; Lu JH
Phytomedicine; 2022 Jul; 101():154125. PubMed ID: 35525236
[TBL] [Abstract][Full Text] [Related]
11. Insulin Resistance Promotes Parkinson's Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling.
Hong CT; Chen KY; Wang W; Chiu JY; Wu D; Chao TY; Hu CJ; Chau KD; Bamodu OA
Cells; 2020 Mar; 9(3):. PubMed ID: 32192190
[No Abstract] [Full Text] [Related]
12. Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo.
Oueslati A; Schneider BL; Aebischer P; Lashuel HA
Proc Natl Acad Sci U S A; 2013 Oct; 110(41):E3945-54. PubMed ID: 23983262
[TBL] [Abstract][Full Text] [Related]
13. Genomic DNA levels of mutant alpha-synuclein correlate with non-motor symptoms in an A53T Parkinson's disease mouse model.
Wang W; Song N; Jia F; Tang T; Bao W; Zuo C; Xie J; Jiang H
Neurochem Int; 2018 Mar; 114():71-79. PubMed ID: 29355568
[TBL] [Abstract][Full Text] [Related]
14. Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model.
Gan L; Vargas MR; Johnson DA; Johnson JA
J Neurosci; 2012 Dec; 32(49):17775-87. PubMed ID: 23223297
[TBL] [Abstract][Full Text] [Related]
15. Phosphorylation of Parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T α-synuclein model of Parkinson's disease.
Chen J; Ren Y; Gui C; Zhao M; Wu X; Mao K; Li W; Zou F
Cell Death Dis; 2018 Jun; 9(6):700. PubMed ID: 29899409
[TBL] [Abstract][Full Text] [Related]
16. Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines.
Woerman AL; Oehler A; Kazmi SA; Lee J; Halliday GM; Middleton LT; Gentleman SM; Mordes DA; Spina S; Grinberg LT; Olson SH; Prusiner SB
Acta Neuropathol; 2019 Mar; 137(3):437-454. PubMed ID: 30690664
[TBL] [Abstract][Full Text] [Related]
17. Mechanisms underlying extensive Ser129-phosphorylation in α-synuclein aggregates.
Arawaka S; Sato H; Sasaki A; Koyama S; Kato T
Acta Neuropathol Commun; 2017 Jun; 5(1):48. PubMed ID: 28619113
[TBL] [Abstract][Full Text] [Related]
18. MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian.
Mo M; Xiao Y; Huang S; Cen L; Chen X; Zhang L; Luo Q; Li S; Yang X; Lin X; Xu P
Oncotarget; 2017 Jan; 8(1):15-28. PubMed ID: 27965467
[TBL] [Abstract][Full Text] [Related]
19. Iron-induced oxidative stress contributes to α-synuclein phosphorylation and up-regulation via polo-like kinase 2 and casein kinase 2.
Wang R; Wang Y; Qu L; Chen B; Jiang H; Song N; Xie J
Neurochem Int; 2019 May; 125():127-135. PubMed ID: 30797969
[TBL] [Abstract][Full Text] [Related]
20. Monoamine Oxidase-B Inhibition Facilitates α-Synuclein Secretion
Nakamura Y; Arawaka S; Sato H; Sasaki A; Shigekiyo T; Takahata K; Tsunekawa H; Kato T
J Neurosci; 2021 Sep; 41(35):7479-7491. PubMed ID: 34290084
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]