These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 38177498)

  • 1. The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells.
    Neidhardt L; Cloots E; Friemel N; Weiss CAM; Harding HP; McLaughlin SH; Janssens S; Ron D
    EMBO J; 2024 Mar; 43(5):719-753. PubMed ID: 38177498
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2.
    Cloots E; Guilbert P; Provost M; Neidhardt L; Van de Velde E; Fayazpour F; De Sutter D; Savvides SN; Eyckerman S; Janssens S
    EMBO J; 2024 Mar; 43(5):695-718. PubMed ID: 38177501
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR.
    Amin-Wetzel N; Neidhardt L; Yan Y; Mayer MP; Ron D
    Elife; 2019 Dec; 8():. PubMed ID: 31873072
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Direct association of unfolded proteins with mammalian ER stress sensor, IRE1β.
    Oikawa D; Kitamura A; Kinjo M; Iwawaki T
    PLoS One; 2012; 7(12):e51290. PubMed ID: 23236464
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Negative feedback by IRE1β optimizes mucin production in goblet cells.
    Tsuru A; Fujimoto N; Takahashi S; Saito M; Nakamura D; Iwano M; Iwawaki T; Kadokura H; Ron D; Kohno K
    Proc Natl Acad Sci U S A; 2013 Feb; 110(8):2864-9. PubMed ID: 23386727
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The ER stress transducer IRE1β is required for airway epithelial mucin production.
    Martino MB; Jones L; Brighton B; Ehre C; Abdulah L; Davis CW; Ron D; O'Neal WK; Ribeiro CM
    Mucosal Immunol; 2013 May; 6(3):639-54. PubMed ID: 23168839
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human AGR2 Deficiency Causes Mucus Barrier Dysfunction and Infantile Inflammatory Bowel Disease.
    Al-Shaibi AA; Abdel-Motal UM; Hubrack SZ; Bullock AN; Al-Marri AA; Agrebi N; Al-Subaiey AA; Ibrahim NA; Charles AK; ; Elawad M; Uhlig HH; Lo B
    Cell Mol Gastroenterol Hepatol; 2021; 12(5):1809-1830. PubMed ID: 34237462
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress.
    Grey MJ; Cloots E; Simpson MS; LeDuc N; Serebrenik YV; De Luca H; De Sutter D; Luong P; Thiagarajah JR; Paton AW; Paton JC; Seeliger MA; Eyckerman S; Janssens S; Lencer WI
    J Cell Biol; 2020 Feb; 219(2):. PubMed ID: 31985747
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response.
    Amin-Wetzel N; Saunders RA; Kamphuis MJ; Rato C; Preissler S; Harding HP; Ron D
    Cell; 2017 Dec; 171(7):1625-1637.e13. PubMed ID: 29198525
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Experimental approaches for elucidation of stress-sensing mechanisms of the IRE1 family proteins.
    Oikawa D; Kimata Y
    Methods Enzymol; 2011; 490():195-216. PubMed ID: 21266252
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of a Rapid in vivo Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response Using Medaka Fish.
    Jin B; Ishikawa T; Taniguchi M; Ninagawa S; Okada T; Kagaya S; Mori K
    Cell Struct Funct; 2020 Feb; 45(1):23-31. PubMed ID: 31875595
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of a Chemical Toolset for Studying the Paralog-Specific Function of IRE1.
    Feldman HC; Vidadala VN; Potter ZE; Papa FR; Backes BJ; Maly DJ
    ACS Chem Biol; 2019 Dec; 14(12):2595-2605. PubMed ID: 31609569
    [TBL] [Abstract][Full Text] [Related]  

  • 13. T-2 toxin inhibits the production of mucin via activating the IRE1/XBP1 pathway.
    Lin R; Sun Y; Ye W; Zheng T; Wen J; Deng Y
    Toxicology; 2019 Aug; 424():152230. PubMed ID: 31170431
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evolutionary Aspects of the Unfolded Protein Response.
    Mori K
    Cold Spring Harb Perspect Biol; 2022 Dec; 14(12):. PubMed ID: 35940910
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α.
    Sepulveda D; Rojas-Rivera D; Rodríguez DA; Groenendyk J; Köhler A; Lebeaupin C; Ito S; Urra H; Carreras-Sureda A; Hazari Y; Vasseur-Cognet M; Ali MMU; Chevet E; Campos G; Godoy P; Vaisar T; Bailly-Maitre B; Nagata K; Michalak M; Sierralta J; Hetz C
    Mol Cell; 2018 Jan; 69(2):238-252.e7. PubMed ID: 29351844
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AGR2, an endoplasmic reticulum protein, is secreted into the gastrointestinal mucus.
    Bergström JH; Berg KA; Rodríguez-Piñeiro AM; Stecher B; Johansson ME; Hansson GC
    PLoS One; 2014; 9(8):e104186. PubMed ID: 25111734
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides.
    Bergmann TJ; Fregno I; Fumagalli F; Rinaldi A; Bertoni F; Boersema PJ; Picotti P; Molinari M
    J Biol Chem; 2018 Apr; 293(15):5600-5612. PubMed ID: 29453283
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice.
    Zhao F; Edwards R; Dizon D; Afrasiabi K; Mastroianni JR; Geyfman M; Ouellette AJ; Andersen B; Lipkin SM
    Dev Biol; 2010 Feb; 338(2):270-9. PubMed ID: 20025862
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum.
    Liu CY; Schröder M; Kaufman RJ
    J Biol Chem; 2000 Aug; 275(32):24881-5. PubMed ID: 10835430
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Elucidation of the AGR2 Interactome in Esophageal Adenocarcinoma Cells Identifies a Redox-Sensitive Chaperone Hub for the Quality Control of MUC-5AC.
    Worfolk JC; Bell S; Simpson LD; Carne NA; Francis SL; Engelbertsen V; Brown AP; Walker J; Viswanath YK; Benham AM
    Antioxid Redox Signal; 2019 Nov; 31(15):1117-1132. PubMed ID: 31436131
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 10.