129 related articles for article (PubMed ID: 38183983)
21. iRhom2 inhibits bile duct obstruction-induced liver fibrosis.
Sundaram B; Behnke K; Belancic A; Al-Salihi MA; Thabet Y; Polz R; Pellegrino R; Zhuang Y; Shinde PV; Xu HC; Vasilevska J; Longerich T; Herebian D; Mayatepek E; Bock HH; May P; Kordes C; Aghaeepour N; Mak TW; Keitel V; Häussinger D; Scheller J; Pandyra AA; Lang KS; Lang PA
Sci Signal; 2019 Oct; 12(605):. PubMed ID: 31662486
[TBL] [Abstract][Full Text] [Related]
22. RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome.
Blaydon DC; Etheridge SL; Risk JM; Hennies HC; Gay LJ; Carroll R; Plagnol V; McRonald FE; Stevens HP; Spurr NK; Bishop DT; Ellis A; Jankowski J; Field JK; Leigh IM; South AP; Kelsell DP
Am J Hum Genet; 2012 Feb; 90(2):340-6. PubMed ID: 22265016
[TBL] [Abstract][Full Text] [Related]
23. Mechanistic insight on the role of iRhom2-TNF-α-BAFF signaling pathway in various autoimmune disorders.
Dwivedi SD; Shukla R; Yadav K; Rathor LS; Singh D; Singh MR
Adv Biol Regul; 2024 May; 92():101011. PubMed ID: 38151421
[TBL] [Abstract][Full Text] [Related]
24. iRhom2 Promotes Hepatic Steatosis by Activating MAP3K7-Dependent Pathway.
Xu M; Ge C; Zhu L; Qin Y; Du C; Lou D; Li Q; Hu L; Sun Y; Dai X; Xiong M; Long T; Zhan J; Kuang Q; Li H; Yang Q; Huang P; Teng X; Feng J; Wu Y; Dong W; Wang B; Tan J
Hepatology; 2021 Apr; 73(4):1346-1364. PubMed ID: 32592194
[TBL] [Abstract][Full Text] [Related]
25. Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.
Maney SK; McIlwain DR; Polz R; Pandyra AA; Sundaram B; Wolff D; Ohishi K; Maretzky T; Brooke MA; Evers A; Vasudevan AA; Aghaeepour N; Scheller J; Münk C; Häussinger D; Mak TW; Nolan GP; Kelsell DP; Blobel CP; Lang KS; Lang PA
Sci Signal; 2015 Nov; 8(401):ra109. PubMed ID: 26535007
[TBL] [Abstract][Full Text] [Related]
26. iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Li X; Maretzky T; Weskamp G; Monette S; Qing X; Issuree PD; Crawford HC; McIlwain DR; Mak TW; Salmon JE; Blobel CP
Proc Natl Acad Sci U S A; 2015 May; 112(19):6080-5. PubMed ID: 25918388
[TBL] [Abstract][Full Text] [Related]
27. Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.
Siggs OM; Grieve A; Xu H; Bambrough P; Christova Y; Freeman M
Biol Open; 2014 Nov; 3(12):1151-7. PubMed ID: 25395669
[TBL] [Abstract][Full Text] [Related]
28. Novel functions of inactive rhomboid proteins in immunity and disease.
Geesala R; Issuree PD; Maretzky T
J Leukoc Biol; 2019 Oct; 106(4):823-835. PubMed ID: 31369701
[TBL] [Abstract][Full Text] [Related]
29. Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation.
Christova Y; Adrain C; Bambrough P; Ibrahim A; Freeman M
EMBO Rep; 2013 Oct; 14(10):884-90. PubMed ID: 23969955
[TBL] [Abstract][Full Text] [Related]
30. Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
Tang B; Li X; Maretzky T; Perez-Aguilar JM; McIlwain D; Xie Y; Zheng Y; Mak TW; Weinstein H; Blobel CP
FASEB J; 2020 Apr; 34(4):4956-4969. PubMed ID: 32103528
[TBL] [Abstract][Full Text] [Related]
31. Deficiency in Inactive Rhomboid Protein2 (iRhom2) Alleviates Alcoholic Liver Fibrosis by Suppressing Inflammation and Oxidative Stress.
Liu Y; Kuang Q; Dai X; Zhan M; Zhou L; Zhu L; Wang B
Int J Mol Sci; 2022 Jul; 23(14):. PubMed ID: 35887045
[TBL] [Abstract][Full Text] [Related]
32. Investigating isoform switching in
Masood M; Masood MBE; Us Subah N; Shabbir M; Paracha RZ; Rafiq M
PeerJ; 2022; 10():e14124. PubMed ID: 36452073
[TBL] [Abstract][Full Text] [Related]
33. iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.
Qing X; Rogers L; Mortha A; Lavin Y; Redecha P; Issuree PD; Maretzky T; Merad M; McIlwain D; Mak TW; Overall CM; Blobel CP; Salmon JE
Eur J Immunol; 2016 Dec; 46(12):2737-2748. PubMed ID: 27601030
[TBL] [Abstract][Full Text] [Related]
34. Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE.
Cavadas M; Oikonomidi I; Gaspar CJ; Burbridge E; Badenes M; Félix I; Bolado A; Hu T; Bileck A; Gerner C; Domingos PM; von Kriegsheim A; Adrain C
Cell Rep; 2017 Oct; 21(3):745-757. PubMed ID: 29045841
[TBL] [Abstract][Full Text] [Related]
35. Endoplasmic reticulum stress-induced iRhom2 up-regulation promotes macrophage-regulated cardiac inflammation and lipid deposition in high fat diet (HFD)-challenged mice: Intervention of fisetin and metformin.
Ge CX; Xu MX; Qin YT; Gu TT; Lou DS; Li Q; Hu LF; Wang BC; Tan J
Free Radic Biol Med; 2019 Sep; 141():67-83. PubMed ID: 31153974
[TBL] [Abstract][Full Text] [Related]
36. Inflammatory activation of surface molecule shedding by upregulation of the pseudoprotease iRhom2 in colon epithelial cells.
Giese AA; Babendreyer A; Krappen P; Gross A; Strnad P; Düsterhöft S; Ludwig A
Sci Rep; 2021 Dec; 11(1):24230. PubMed ID: 34930929
[TBL] [Abstract][Full Text] [Related]
37. iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Maretzky T; McIlwain DR; Issuree PD; Li X; Malapeira J; Amin S; Lang PA; Mak TW; Blobel CP
Proc Natl Acad Sci U S A; 2013 Jul; 110(28):11433-8. PubMed ID: 23801765
[TBL] [Abstract][Full Text] [Related]
38. iRhom2 loss alleviates renal injury in long-term PM2.5-exposed mice by suppression of inflammation and oxidative stress.
Chenxu G; Minxuan X; Yuting Q; Tingting G; Jinxiao L; Mingxing W; Sujun W; Yongjie M; Deshuai L; Qiang L; Linfeng H; Jun T
Redox Biol; 2018 Oct; 19():147-157. PubMed ID: 30165303
[TBL] [Abstract][Full Text] [Related]
39. iRhom2 mutation leads to aberrant hair follicle differentiation in mice.
Leilei Y; Bing L; Yang L; Shaoxia W; Yuan X; Dongping W; Huahu Y; Shichen S; Guangzhou Z; Ruiyun P; Lin Z; Wenlong L
PLoS One; 2014; 9(12):e115114. PubMed ID: 25546423
[TBL] [Abstract][Full Text] [Related]
40. Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
Li X; Maretzky T; Perez-Aguilar JM; Monette S; Weskamp G; Le Gall S; Beutler B; Weinstein H; Blobel CP
J Cell Sci; 2017 Mar; 130(5):868-878. PubMed ID: 28104813
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
