186 related articles for article (PubMed ID: 38184999)
1. Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH.
Fernández-Ginés R; Encinar JA; Escoll M; Carnicero-Senabre D; Jiménez-Villegas J; García-Yagüe ÁJ; González-Rodríguez Á; Garcia-Martinez I; Valverde ÁM; Rojo AI; Cuadrado A
Redox Biol; 2024 Feb; 69():103027. PubMed ID: 38184999
[TBL] [Abstract][Full Text] [Related]
2. Nonalcoholic steatohepatitis and mechanisms by which it is ameliorated by activation of the CNC-bZIP transcription factor Nrf2.
Bathish B; Robertson H; Dillon JF; Dinkova-Kostova AT; Hayes JD
Free Radic Biol Med; 2022 Aug; 188():221-261. PubMed ID: 35728768
[TBL] [Abstract][Full Text] [Related]
3. An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti-inflammatory responses in mouse liver.
Fernández-Ginés R; Encinar JA; Hayes JD; Oliva B; Rodríguez-Franco MI; Rojo AI; Cuadrado A
Redox Biol; 2022 Sep; 55():102396. PubMed ID: 35839629
[TBL] [Abstract][Full Text] [Related]
4. Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis.
Mohs A; Otto T; Schneider KM; Peltzer M; Boekschoten M; Holland CH; Hudert CA; Kalveram L; Wiegand S; Saez-Rodriguez J; Longerich T; Hengstler JG; Trautwein C
J Hepatol; 2021 Mar; 74(3):638-648. PubMed ID: 33342543
[TBL] [Abstract][Full Text] [Related]
5. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis.
Lee DH; Han DH; Nam KT; Park JS; Kim SH; Lee M; Kim G; Min BS; Cha BS; Lee YS; Sung SH; Jeong H; Ji HW; Lee MJ; Lee JS; Lee HY; Chun Y; Kim J; Komatsu M; Lee YH; Bae SH
Free Radic Biol Med; 2016 Oct; 99():520-532. PubMed ID: 27634173
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of glycogen synthase kinase-3 enhances NRF2 protein stability, nuclear localisation and target gene transcription in pancreatic beta cells.
Patibandla C; van Aalten L; Dinkova-Kostova AT; Honda T; Cuadrado A; Fernández-Ginés R; McNeilly AD; Hayes JD; Cantley J; Sutherland C
Redox Biol; 2024 May; 71():103117. PubMed ID: 38479223
[TBL] [Abstract][Full Text] [Related]
7. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model.
Shimozono R; Asaoka Y; Yoshizawa Y; Aoki T; Noda H; Yamada M; Kaino M; Mochizuki H
Mol Pharmacol; 2013 Jul; 84(1):62-70. PubMed ID: 23592516
[TBL] [Abstract][Full Text] [Related]
8. Hepatocyte-specific Keap1 deletion reduces liver steatosis but not inflammation during non-alcoholic steatohepatitis development.
Ramadori P; Drescher H; Erschfeld S; Schumacher F; Berger C; Fragoulis A; Schenkel J; Kensler TW; Wruck CJ; Trautwein C; Kroy DC; Streetz KL
Free Radic Biol Med; 2016 Feb; 91():114-26. PubMed ID: 26698665
[TBL] [Abstract][Full Text] [Related]
9. Immunohistochemical expression of NRF2 is correlated with the magnitude of inflammation and fibrosis in chronic liver disease.
To K; Okada K; Watahiki T; Suzuki H; Tsuchiya K; Tokushige K; Yamamoto M; Ariizumi SI; Shoda J
Cancer Med; 2023 Oct; 12(19):19423-19437. PubMed ID: 37732511
[TBL] [Abstract][Full Text] [Related]
10. Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress.
Zhang MH; Li J; Zhu XY; Zhang YQ; Ye ST; Leng YR; Yang T; Zhang H; Kong LY
Free Radic Biol Med; 2021 Feb; 164():1-12. PubMed ID: 33388433
[TBL] [Abstract][Full Text] [Related]
11. Protective effects of scutellaria-coptis herb couple against non-alcoholic steatohepatitis via activating NRF2 and FXR pathways in vivo and in vitro.
Xue Y; Wei Y; Cao L; Shi M; Sheng J; Xiao Q; Cheng Z; Luo T; Jiao Q; Wu A; Chen C; Zhong L; Zhang C
J Ethnopharmacol; 2024 Jan; 318(Pt A):116933. PubMed ID: 37482263
[TBL] [Abstract][Full Text] [Related]
12. Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2).
Sharma RS; Harrison DJ; Kisielewski D; Cassidy DM; McNeilly AD; Gallagher JR; Walsh SV; Honda T; McCrimmon RJ; Dinkova-Kostova AT; Ashford MLJ; Dillon JF; Hayes JD
Cell Mol Gastroenterol Hepatol; 2018 Mar; 5(3):367-398. PubMed ID: 29552625
[TBL] [Abstract][Full Text] [Related]
13. Nomilin and its analogue obacunone alleviate NASH and hepatic fibrosis in mice via enhancing antioxidant and anti-inflammation capacity.
Han Y; Luo L; Li H; Zhang L; Yan Y; Fang M; Yu J; Gao X; Liu Y; Huang C; Fan S
Biofactors; 2023; 49(6):1189-1204. PubMed ID: 37401768
[TBL] [Abstract][Full Text] [Related]
14. Selective disruption of NRF2-KEAP1 interaction leads to NASH resolution and reduction of liver fibrosis in mice.
Seedorf K; Weber C; Vinson C; Berger S; Vuillard LM; Kiss A; Creusot S; Broux O; Geant A; Ilic C; Lemaitre K; Richard J; Hammoutene A; Mahieux J; Martiny V; Durand D; Melchiore F; Nyerges M; Paradis V; Provost N; Duvivier V; Delerive P
JHEP Rep; 2023 Apr; 5(4):100651. PubMed ID: 36866391
[TBL] [Abstract][Full Text] [Related]
15. Nanoplastic propels diet-induced NAFL to NASH via ER-mitochondrial tether-controlled redox switch.
Wei J; Liu J; Wang H; Wen K; Ni X; Lin Y; Huang J; You X; Lei Z; Li J; Shen H; Lin Y
J Hazard Mater; 2024 Mar; 465():133142. PubMed ID: 38061129
[TBL] [Abstract][Full Text] [Related]
16. Activation of the Nrf2-ARE pathway in hepatocytes protects against steatosis in nutritionally induced non-alcoholic steatohepatitis in mice.
Lee LY; Köhler UA; Zhang L; Roenneburg D; Werner S; Johnson JA; Foley DP
Toxicol Sci; 2014 Dec; 142(2):361-74. PubMed ID: 25294219
[TBL] [Abstract][Full Text] [Related]
17. Repositioning of niclosamide ethanolamine (NEN), an anthelmintic drug, for the treatment of lipotoxicity.
Park JS; Lee YS; Lee DH; Bae SH
Free Radic Biol Med; 2019 Jun; 137():143-157. PubMed ID: 31035006
[TBL] [Abstract][Full Text] [Related]
18. Bardoxolone ameliorates TGF-β1-associated renal fibrosis through Nrf2/Smad7 elevation.
Song MK; Lee JH; Ryoo IG; Lee SH; Ku SK; Kwak MK
Free Radic Biol Med; 2019 Jul; 138():33-42. PubMed ID: 31059771
[TBL] [Abstract][Full Text] [Related]
19. Flavonoids from Scutellaria amoena C. H. Wright alleviate mitochondrial dysfunction and regulate oxidative stress via Keap1/Nrf2/HO-1 axis in rats with high-fat diet-induced nonalcoholic steatohepatitis.
Fang QL; Qiao X; Yin XQ; Zeng YC; Du CH; Xue YM; Zhao XJ; Hu CY; Huang F; Lin YP
Biomed Pharmacother; 2023 Feb; 158():114160. PubMed ID: 36571996
[TBL] [Abstract][Full Text] [Related]
20. Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver disease.
Liu P; Anandhan A; Chen J; Shakya A; Dodson M; Ooi A; Chapman E; White E; Garcia JG; Zhang DD
Redox Biol; 2023 Feb; 59():102570. PubMed ID: 36495698
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]