These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 38185231)

  • 1. A navitoclax-loaded nanodevice targeting matrix metalloproteinase-3 for the selective elimination of senescent cells.
    Escriche-Navarro B; Garrido E; Sancenón F; García-Fernández A; Martínez-Máñez R
    Acta Biomater; 2024 Mar; 176():405-416. PubMed ID: 38185231
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity.
    González-Gualda E; Pàez-Ribes M; Lozano-Torres B; Macias D; Wilson JR; González-López C; Ou HL; Mirón-Barroso S; Zhang Z; Lérida-Viso A; Blandez JF; Bernardos A; Sancenón F; Rovira M; Fruk L; Martins CP; Serrano M; Doherty GJ; Martínez-Máñez R; Muñoz-Espín D
    Aging Cell; 2020 Apr; 19(4):e13142. PubMed ID: 32233024
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemical Strategies for the Detection and Elimination of Senescent Cells.
    García-Fleitas J; García-Fernández A; Martí-Centelles V; Sancenón F; Bernardos A; Martínez-Máñez R
    Acc Chem Res; 2024 May; 57(9):1238-1253. PubMed ID: 38604701
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combination of palbociclib with navitoclax based-therapies enhances in vivo antitumoral activity in triple-negative breast cancer.
    Estepa-Fernández A; García-Fernández A; Lérida-Viso A; Blandez JF; Galiana I; Sancenon-Galarza F; Orzáez M; Martínez-Máñez R
    Pharmacol Res; 2023 Jan; 187():106628. PubMed ID: 36566002
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Androgen-deprivation induced senescence in prostate cancer cells is permissive for the development of castration-resistance but susceptible to senolytic therapy.
    Carpenter V; Saleh T; Min Lee S; Murray G; Reed J; Souers A; Faber AC; Harada H; Gewirtz DA
    Biochem Pharmacol; 2021 Nov; 193():114765. PubMed ID: 34536356
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Differential Effect of Senolytics on SASP Cytokine Secretion and Regulation of EMT by CAFs.
    Bogdanova DA; Kolosova ED; Pukhalskaia TV; Levchuk KA; Demidov ON; Belotserkovskaya EV
    Int J Mol Sci; 2024 Apr; 25(7):. PubMed ID: 38612842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pan-mTOR inhibitors sensitize the senolytic activity of navitoclax via mTORC2 inhibition-mediated apoptotic signaling.
    Xu W; Zhao T; Chen H; Huang N; Gong H; Zhang J; Yang Y; Li T; Zhang G; Gong C; Yang M; Xiao H
    Biochem Pharmacol; 2022 Jun; 200():115045. PubMed ID: 35439535
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors.
    Zhu Y; Tchkonia T; Fuhrmann-Stroissnigg H; Dai HM; Ling YY; Stout MB; Pirtskhalava T; Giorgadze N; Johnson KO; Giles CB; Wren JD; Niedernhofer LJ; Robbins PD; Kirkland JL
    Aging Cell; 2016 Jun; 15(3):428-35. PubMed ID: 26711051
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Controlled induction and targeted elimination of p16
    Sessions GA; Copp ME; Liu JY; Sinkler MA; D'Costa S; Diekman BO
    FASEB J; 2019 Nov; 33(11):12364-12373. PubMed ID: 31408372
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice.
    Tarantini S; Balasubramanian P; Delfavero J; Csipo T; Yabluchanskiy A; Kiss T; Nyúl-Tóth Á; Mukli P; Toth P; Ahire C; Ungvari A; Benyo Z; Csiszar A; Ungvari Z
    Geroscience; 2021 Oct; 43(5):2427-2440. PubMed ID: 34427858
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax.
    Faakye J; Nyúl-Tóth Á; Muranyi M; Gulej R; Csik B; Shanmugarama S; Tarantini S; Negri S; Prodan C; Mukli P; Yabluchanskiy A; Conley S; Toth P; Csiszar A; Ungvari Z
    Geroscience; 2024 Feb; 46(1):21-37. PubMed ID: 38044400
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Navitoclax (ABT263) reduces inflammation and promotes chondrogenic phenotype by clearing senescent osteoarthritic chondrocytes in osteoarthritis.
    Yang H; Chen C; Chen H; Duan X; Li J; Zhou Y; Zeng W; Yang L
    Aging (Albany NY); 2020 Jul; 12(13):12750-12770. PubMed ID: 32611834
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of matrix metalloproteinase expression by selective clearing of senescent dermal fibroblasts attenuates ultraviolet-induced photoaging.
    Kim H; Jang J; Song MJ; Park CH; Lee DH; Lee SH; Chung JH
    Biomed Pharmacother; 2022 Jun; 150():113034. PubMed ID: 35489284
    [TBL] [Abstract][Full Text] [Related]  

  • 14. EA.hy926 Cells and HUVECs Share Similar Senescence Phenotypes but Respond Differently to the Senolytic Drug ABT-263.
    Abdelgawad IY; Agostinucci K; Ismail SG; Grant MKO; Zordoky BN
    Cells; 2022 Jun; 11(13):. PubMed ID: 35805077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence.
    Fletcher-Sananikone E; Kanji S; Tomimatsu N; Di Cristofaro LFM; Kollipara RK; Saha D; Floyd JR; Sung P; Hromas R; Burns TC; Kittler R; Habib AA; Mukherjee B; Burma S
    Cancer Res; 2021 Dec; 81(23):5935-5947. PubMed ID: 34580063
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Androgen deprivation-induced senescence confers sensitivity to a senolytic strategy in prostate cancer.
    Carpenter V; Saleh T; Chakraborty E; Min Lee S; Murray G; Reed J; Souers A; Faber AC; Harada H; Gewirtz DA
    Biochem Pharmacol; 2024 Aug; 226():116385. PubMed ID: 38909784
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of radiation-induced micronuclei associated with premature senescence, and their selective removal by senolytic drug, ABT-263.
    Suzuki K; Kawamura K; Ujiie R; Nakayama T; Mitsutake N
    Mutat Res Genet Toxicol Environ Mutagen; 2022; 876-877():503448. PubMed ID: 35483779
    [TBL] [Abstract][Full Text] [Related]  

  • 18. From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs.
    L'Hôte V; Mann C; Thuret JY
    Open Biol; 2022 Sep; 12(9):220171. PubMed ID: 36128715
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain.
    Gulej R; Nyúl-Tóth Á; Ahire C; DelFavero J; Balasubramanian P; Kiss T; Tarantini S; Benyo Z; Pacher P; Csik B; Yabluchanskiy A; Mukli P; Kuan-Celarier A; Krizbai IA; Campisi J; Sonntag WE; Csiszar A; Ungvari Z
    Geroscience; 2023 Oct; 45(5):2983-3002. PubMed ID: 37642933
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Abrogation of Cellular Senescence Induced by Temozolomide in Glioblastoma Cells: Search for Senolytics.
    Beltzig L; Christmann M; Kaina B
    Cells; 2022 Aug; 11(16):. PubMed ID: 36010664
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.