BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 38186307)

  • 1. NRF2 activation in BON‑1 neuroendocrine cancer cells reduces the cytotoxic effects of a novel Ruthenium(II)‑curcumin compound: A pilot study.
    Garufi A; Pettinari R; Monteonofrio L; Puliani G; Virdia I; Appetecchia M; Marchetti F; Cirone M; Soddu S; D'Orazi G
    Oncol Rep; 2024 Feb; 51(2):. PubMed ID: 38186307
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status.
    Garufi A; Baldari S; Pettinari R; Gilardini Montani MS; D'Orazi V; Pistritto G; Crispini A; Giorno E; Toietta G; Marchetti F; Cirone M; D'Orazi G
    J Exp Clin Cancer Res; 2020 Jun; 39(1):122. PubMed ID: 32605658
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Impact of NRF2 Inhibition on Drug-Induced Colon Cancer Cell Death and p53 Activity: A Pilot Study.
    Garufi A; Pistritto G; D'Orazi V; Cirone M; D'Orazi G
    Biomolecules; 2022 Mar; 12(3):. PubMed ID: 35327653
    [TBL] [Abstract][Full Text] [Related]  

  • 4. P62/SQSTM1/Keap1/NRF2 Axis Reduces Cancer Cells Death-Sensitivity in Response to Zn(II)-Curcumin Complex.
    Garufi A; Giorno E; Gilardini Montani MS; Pistritto G; Crispini A; Cirone M; D'Orazi G
    Biomolecules; 2021 Feb; 11(3):. PubMed ID: 33669070
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nuclear factor erythroid 2 (NF-E2) p45-related factor 2 interferes with homeodomain-interacting protein kinase 2/p53 activity to impair solid tumors chemosensitivity.
    D'Orazi G; Garufi A; Cirone M
    IUBMB Life; 2020 Aug; 72(8):1634-1639. PubMed ID: 32593231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1.
    Reuther C; Heinzle V; Nölting S; Herterich S; Hahner S; Halilovic E; Jeay S; Wuerthner JU; Aristizabal Prada ET; Spöttl G; Maurer J; Auernhammer CJ
    Neuroendocrinology; 2018; 106(1):1-19. PubMed ID: 27871087
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Curcumin induces p53-independent inactivation of Nrf2 during oxidative stress-induced apoptosis.
    Méndez-García LA; Martínez-Castillo M; Villegas-Sepúlveda N; Orozco L; Córdova EJ
    Hum Exp Toxicol; 2019 Aug; 38(8):951-961. PubMed ID: 31018701
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NRF2 and Bip Interconnection Mediates Resistance to the Organometallic Ruthenium-Cymene Bisdemethoxycurcumin Complex Cytotoxicity in Colon Cancer Cells.
    Garufi A; Pettinari R; Marchetti F; Cirone M; D'Orazi G
    Biomedicines; 2023 Feb; 11(2):. PubMed ID: 36831129
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nrf2 is a key factor in the reversal effect of curcumin on multidrug resistance in the HCT‑8/5‑Fu human colorectal cancer cell line.
    Zhang C; He LJ; Ye HZ; Liu DF; Zhu YB; Miao DD; Zhang SP; Chen YY; Jia YW; Shen J; Liu XP
    Mol Med Rep; 2018 Dec; 18(6):5409-5416. PubMed ID: 30365132
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Curcumin attenuates diphenyl phosphate-induced apoptosis in GC-2spd(ts) cells through activated autophagy via the Nrf2/P53 pathway.
    Wei L; Li S; Ma Y; Ye S; Yuan Y; Zeng Y; Raza T; Xiao F
    Environ Toxicol; 2024 Apr; 39(4):2032-2042. PubMed ID: 38095090
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.
    Iuchi K; Tasaki Y; Shirai S; Hisatomi H
    Biomed Pharmacother; 2020 May; 125():109928. PubMed ID: 32004978
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis.
    Liu C; Rokavec M; Huang Z; Hermeking H
    Cell Death Differ; 2023 Jul; 30(7):1771-1785. PubMed ID: 37210578
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling.
    Watson JL; Greenshields A; Hill R; Hilchie A; Lee PW; Giacomantonio CA; Hoskin DW
    Mol Carcinog; 2010 Jan; 49(1):13-24. PubMed ID: 19676105
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutant p53 confers chemoresistance in non-small cell lung cancer by upregulating Nrf2.
    Tung MC; Lin PL; Wang YC; He TY; Lee MC; Yeh SD; Chen CY; Lee H
    Oncotarget; 2015 Dec; 6(39):41692-705. PubMed ID: 26497680
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HIPK2 is a potential predictive marker of a favorable response for adjuvant chemotherapy in stage II colorectal cancer.
    Verdina A; Di Segni M; Amoreo CA; Sperduti I; Buglioni S; Mottolese M; Di Rocco G; Soddu S
    Oncol Rep; 2021 Mar; 45(3):899-910. PubMed ID: 33650652
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nrf2 Knockdown Disrupts the Protective Effect of Curcumin on Alcohol-Induced Hepatocyte Necroptosis.
    Lu C; Xu W; Zhang F; Shao J; Zheng S
    Mol Pharm; 2016 Dec; 13(12):4043-4053. PubMed ID: 27764939
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metformin induces microRNA-34a to downregulate the Sirt1/Pgc-1α/Nrf2 pathway, leading to increased susceptibility of wild-type p53 cancer cells to oxidative stress and therapeutic agents.
    Do MT; Kim HG; Choi JH; Jeong HG
    Free Radic Biol Med; 2014 Sep; 74():21-34. PubMed ID: 24970682
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ruthenium Complexes Induce HepG2 Human Hepatocellular Carcinoma Cell Apoptosis and Inhibit Cell Migration and Invasion through Regulation of the Nrf2 Pathway.
    Lu Y; Shen T; Yang H; Gu W
    Int J Mol Sci; 2016 May; 17(5):. PubMed ID: 27213353
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclometalated Ru(II)-isoquinoline complexes overcome cisplatin resistance of A549/DDP cells by downregulation of Nrf2 via Akt/GSK-3β/Fyn pathway.
    Chen L; Wang J; Cai X; Chen S; Zhang J; Li B; Chen W; Guo X; Luo H; Chen J
    Bioorg Chem; 2022 Feb; 119():105516. PubMed ID: 34856444
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Epigenetics Reactivation of Nrf2 in Prostate TRAMP C1 Cells by Curcumin Analogue FN1.
    Li W; Pung D; Su ZY; Guo Y; Zhang C; Yang AY; Zheng X; Du ZY; Zhang K; Kong AN
    Chem Res Toxicol; 2016 Apr; 29(4):694-703. PubMed ID: 26991801
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.