170 related articles for article (PubMed ID: 38187650)
1. Activated PI3Kδ specifically perturbs mouse Treg homeostasis and function leading to immune dysregulation.
Singh AK; Qureshah FA; Drow T; Hou B; Rawlings DJ
bioRxiv; 2023 Dec; ():. PubMed ID: 38187650
[TBL] [Abstract][Full Text] [Related]
2. Activated PI3Kδ Specifically Perturbs Mouse Regulatory T Cell Homeostasis and Function Leading to Immune Dysregulation.
Singh AK; Al Qureshah F; Drow T; Hou B; Rawlings DJ
J Immunol; 2024 Jun; ():. PubMed ID: 38829130
[TBL] [Abstract][Full Text] [Related]
3. Activated PI3Kδ signals compromise plasma cell survival via limiting autophagy and increasing ER stress.
Al Qureshah F; Sagadiev S; Thouvenel CD; Liu S; Hua Z; Hou B; Acharya M; James RG; Rawlings DJ
J Exp Med; 2021 Dec; 218(12):. PubMed ID: 34586341
[TBL] [Abstract][Full Text] [Related]
4. Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation.
Stark AK; Davenport ECM; Patton DT; Scudamore CL; Vanhaesebroeck B; Veldhoen M; Garden OA; Okkenhaug K
J Immunol; 2020 Jul; 205(1):78-89. PubMed ID: 32414808
[TBL] [Abstract][Full Text] [Related]
5. Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4
Bier J; Rao G; Payne K; Brigden H; French E; Pelham SJ; Lau A; Lenthall H; Edwards ESJ; Smart JM; Cole TS; Choo S; Joshi AY; Abraham RS; O'Sullivan M; Boztug K; Meyts I; Gray PE; Berglund LJ; Hsu P; Wong M; Holland SM; Notarangelo LD; Uzel G; Ma CS; Brink R; Tangye SG; Deenick EK
J Allergy Clin Immunol; 2019 Jul; 144(1):236-253. PubMed ID: 30738173
[TBL] [Abstract][Full Text] [Related]
6. Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection.
Coutinho A; Caramalho I; Seixas E; Demengeot J
Curr Top Microbiol Immunol; 2005; 293():43-71. PubMed ID: 15981475
[TBL] [Abstract][Full Text] [Related]
7. PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8
Cannons JL; Villarino AV; Kapnick SM; Preite S; Shih HY; Gomez-Rodriguez J; Kaul Z; Shibata H; Reilley JM; Huang B; Handon R; McBain IT; Gossa S; Wu T; Su HC; McGavern DB; O'Shea JJ; McGuire PJ; Uzel G; Schwartzberg PL
Cell Rep; 2021 Oct; 37(2):109804. PubMed ID: 34644563
[TBL] [Abstract][Full Text] [Related]
8. Effective "activated PI3Kδ syndrome"-targeted therapy with the PI3Kδ inhibitor leniolisib.
Rao VK; Webster S; Dalm VASH; Šedivá A; van Hagen PM; Holland S; Rosenzweig SD; Christ AD; Sloth B; Cabanski M; Joshi AD; de Buck S; Doucet J; Guerini D; Kalis C; Pylvaenaeinen I; Soldermann N; Kashyap A; Uzel G; Lenardo MJ; Patel DD; Lucas CL; Burkhart C
Blood; 2017 Nov; 130(21):2307-2316. PubMed ID: 28972011
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of phosphoinositide‑3 kinases γ/δ ameliorates pulmonary granuloma by rescuing Treg function in a sarcoidosis model.
Zhang X; Dai Q; Shan J; Zhang S; Zhang B; Liu S; Zhang Y; Wang Y; Li X; Jin X; Liang D; Ding J; Wang Y; Wen Y
Exp Ther Med; 2023 May; 25(5):225. PubMed ID: 37123205
[TBL] [Abstract][Full Text] [Related]
10. PI3K Orchestrates T Follicular Helper Cell Differentiation in a Context Dependent Manner: Implications for Autoimmunity.
Preite S; Huang B; Cannons JL; McGavern DB; Schwartzberg PL
Front Immunol; 2018; 9():3079. PubMed ID: 30666254
[TBL] [Abstract][Full Text] [Related]
11. PI3Kδ inhibition modulates regulatory and effector T-cell differentiation and function in chronic lymphocytic leukemia.
Hanna BS; Roessner PM; Scheffold A; Jebaraj BMC; Demerdash Y; Öztürk S; Lichter P; Stilgenbauer S; Seiffert M
Leukemia; 2019 Jun; 33(6):1427-1438. PubMed ID: 30573773
[TBL] [Abstract][Full Text] [Related]
12. Excessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis.
Ishigame H; Zenewicz LA; Sanjabi S; Licona-Limón P; Nakayama M; Leonard WJ; Flavell RA
Proc Natl Acad Sci U S A; 2013 Apr; 110(17):6961-6. PubMed ID: 23569233
[TBL] [Abstract][Full Text] [Related]
13. A comprehensive review on the role of co-signaling receptors and Treg homeostasis in autoimmunity and tumor immunity.
Kumar P; Bhattacharya P; Prabhakar BS
J Autoimmun; 2018 Dec; 95():77-99. PubMed ID: 30174217
[TBL] [Abstract][Full Text] [Related]
14. Blockade of TGF-β signaling to enhance the antitumor response is accompanied by dysregulation of the functional activity of CD4
Polanczyk MJ; Walker E; Haley D; Guerrouahen BS; Akporiaye ET
J Transl Med; 2019 Jul; 17(1):219. PubMed ID: 31288845
[TBL] [Abstract][Full Text] [Related]
15. Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice.
Suffner J; Hochweller K; Kühnle MC; Li X; Kroczek RA; Garbi N; Hämmerling GJ
J Immunol; 2010 Feb; 184(4):1810-20. PubMed ID: 20083650
[TBL] [Abstract][Full Text] [Related]
16. PI3K pathway defects leading to immunodeficiency and immune dysregulation.
Nunes-Santos CJ; Uzel G; Rosenzweig SD
J Allergy Clin Immunol; 2019 May; 143(5):1676-1687. PubMed ID: 31060715
[TBL] [Abstract][Full Text] [Related]
17. Regulatory function of a novel population of mouse autoantigen-specific Foxp3 regulatory T cells depends on IFN-gamma, NO, and contact with target cells.
Chen C; Liu CP
PLoS One; 2009 Nov; 4(11):e7863. PubMed ID: 19924236
[TBL] [Abstract][Full Text] [Related]
18. Selective deletion of Eos (Ikzf4) in T-regulatory cells leads to loss of suppressive function and development of systemic autoimmunity.
Gokhale AS; Gangaplara A; Lopez-Occasio M; Thornton AM; Shevach EM
J Autoimmun; 2019 Dec; 105():102300. PubMed ID: 31296356
[TBL] [Abstract][Full Text] [Related]
19. Interruption of Thymic Activity in Adult Mice Improves Responses to Tumor Immunotherapy.
Almeida-Santos J; Bergman ML; Cabral IA; Demengeot J
J Immunol; 2021 Mar; 206(5):978-986. PubMed ID: 33472908
[TBL] [Abstract][Full Text] [Related]
20. Differential PI3Kδ Signaling in CD4
Ahmad S; Abu-Eid R; Shrimali R; Webb M; Verma V; Doroodchi A; Berrong Z; Samara R; Rodriguez PC; Mkrtichyan M; Khleif SN
Cancer Res; 2017 Apr; 77(8):1892-1904. PubMed ID: 28108509
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
