BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 38199567)

  • 1. Functional maturation of cytochromes P450 3A4 and 2D6 relies on GAPDH- and Hsp90-Dependent heme allocation.
    Islam S; Jayaram DT; Biswas P; Stuehr DJ
    J Biol Chem; 2024 Feb; 300(2):105633. PubMed ID: 38199567
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Indoleamine dioxygenase and tryptophan dioxygenase activities are regulated through GAPDH- and Hsp90-dependent control of their heme levels.
    Biswas P; Dai Y; Stuehr DJ
    Free Radic Biol Med; 2022 Feb; 180():179-190. PubMed ID: 35051612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dynamic cycling with a unique Hsp90/Hsp70-dependent chaperone machinery and GAPDH is needed for heme insertion and activation of neuronal NO synthase.
    Morishima Y; Lau M; Pratt WB; Osawa Y
    J Biol Chem; 2023 Feb; 299(2):102856. PubMed ID: 36596358
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hsp90 chaperones hemoglobin maturation in erythroid and nonerythroid cells.
    Ghosh A; Garee G; Sweeny EA; Nakamura Y; Stuehr DJ
    Proc Natl Acad Sci U S A; 2018 Feb; 115(6):E1117-E1126. PubMed ID: 29358373
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New roles for GAPDH, Hsp90, and NO in regulating heme allocation and hemeprotein function in mammals.
    Stuehr DJ; Dai Y; Biswas P; Sweeny EA; Ghosh A
    Biol Chem; 2022 Nov; 403(11-12):1005-1015. PubMed ID: 36152339
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hsp90 interacts with inducible NO synthase client protein in its heme-free state and then drives heme insertion by an ATP-dependent process.
    Ghosh A; Chawla-Sarkar M; Stuehr DJ
    FASEB J; 2011 Jun; 25(6):2049-60. PubMed ID: 21357526
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hsp90 in Human Diseases: Molecular Mechanisms to Therapeutic Approaches.
    Sumi MP; Ghosh A
    Cells; 2022 Mar; 11(6):. PubMed ID: 35326427
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Myoglobin maturation is driven by the hsp90 chaperone machinery and by soluble guanylyl cyclase.
    Ghosh A; Dai Y; Biswas P; Stuehr DJ
    FASEB J; 2019 Sep; 33(9):9885-9896. PubMed ID: 31170354
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of hsp90 in heme-dependent activation of apo-neuronal nitric-oxide synthase.
    Billecke SS; Draganov DI; Morishima Y; Murphy PJ; Dunbar AY; Pratt WB; Osawa Y
    J Biol Chem; 2004 Jul; 279(29):30252-8. PubMed ID: 15155759
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content.
    Ghosh A; Stasch JP; Papapetropoulos A; Stuehr DJ
    J Biol Chem; 2014 May; 289(22):15259-71. PubMed ID: 24733395
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction of apo-cytochrome b5 with cytochromes P4503A4 and P45017A: relevance of heme transfer reactions.
    Guryev OL; Gilep AA; Usanov SA; Estabrook RW
    Biochemistry; 2001 Apr; 40(16):5018-31. PubMed ID: 11305918
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inactivation of cytochrome P450 (P450) 3A4 but not P450 3A5 by OSI-930, a thiophene-containing anticancer drug.
    Lin HL; Zhang H; Medower C; Hollenberg PF; Johnson WW
    Drug Metab Dispos; 2011 Feb; 39(2):345-50. PubMed ID: 21068193
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GAPDH is involved in the heme-maturation of myoglobin and hemoglobin.
    Tupta B; Stuehr E; Sumi MP; Sweeny EA; Smith B; Stuehr DJ; Ghosh A
    FASEB J; 2022 Feb; 36(2):e22099. PubMed ID: 34972240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The effects of azole-based heme oxygenase inhibitors on rat cytochromes P450 2E1 and 3A1/2 and human cytochromes P450 3A4 and 2D6.
    Hum M; McLaughlin BE; Roman G; Vlahakis JZ; Szarek WA; Nakatsu K
    J Pharmacol Exp Ther; 2010 Sep; 334(3):981-7. PubMed ID: 20501634
    [TBL] [Abstract][Full Text] [Related]  

  • 15. N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE) a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs.
    Brandes LJ; Queen GM; LaBella FS
    Cancer Chemother Pharmacol; 2000; 45(4):298-304. PubMed ID: 10755318
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modulation of heme/substrate binding cleft of neuronal nitric-oxide synthase (nNOS) regulates binding of Hsp90 and Hsp70 proteins and nNOS ubiquitination.
    Peng HM; Morishima Y; Pratt WB; Osawa Y
    J Biol Chem; 2012 Jan; 287(2):1556-65. PubMed ID: 22128174
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Heat shock protein 90 regulates soluble guanylyl cyclase maturation by a dual mechanism.
    Dai Y; Schlanger S; Haque MM; Misra S; Stuehr DJ
    J Biol Chem; 2019 Aug; 294(35):12880-12891. PubMed ID: 31311859
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.
    Yamazaki H; Gillam EM; Dong MS; Johnson WW; Guengerich FP; Shimada T
    Arch Biochem Biophys; 1997 Jun; 342(2):329-37. PubMed ID: 9186495
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme.
    Ghosh A; Stuehr DJ
    Proc Natl Acad Sci U S A; 2012 Aug; 109(32):12998-3003. PubMed ID: 22837396
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).
    He K; Woolf TF; Hollenberg PF
    J Pharmacol Exp Ther; 1999 Feb; 288(2):791-7. PubMed ID: 9918590
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.