130 related articles for article (PubMed ID: 38218542)
1. GenX analogs exposure induced greater hepatotoxicity than GenX mainly via activation of PPARα pathway while caused hepatomegaly in the absence of PPARα in female mice.
Ren W; Wang Z; Guo H; Gou Y; Dai J; Zhou X; Sheng N
Environ Pollut; 2024 Mar; 344():123314. PubMed ID: 38218542
[TBL] [Abstract][Full Text] [Related]
2. Adverse effects of gestational exposure to hexafluoropropylene oxide trimer acid (HFPO-TA) homologs on maternal, fetal, and placental health in mice.
Zhu B; Sheng N; Dai J
Sci Total Environ; 2024 Feb; 912():169151. PubMed ID: 38065497
[TBL] [Abstract][Full Text] [Related]
3. GenX Disturbs the Indicators of Hepatic Lipid Metabolism Even at Environmental Concentration in Drinking Water via PPARα Signaling Pathways.
Shi W; Zhang Z; Li X; Chen J; Liang X; Li J
Chem Res Toxicol; 2024 Jan; 37(1):98-108. PubMed ID: 38150050
[TBL] [Abstract][Full Text] [Related]
4. Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice.
Attema B; Janssen AWF; Rijkers D; van Schothorst EM; Hooiveld GJEJ; Kersten S
Mol Metab; 2022 Dec; 66():101602. PubMed ID: 36115532
[TBL] [Abstract][Full Text] [Related]
5. Hexafluoropropylene oxide dimer acid (HFPO-DA) induced developmental cardiotoxicity and hepatotoxicity in hatchling chickens: Roles of peroxisome proliferator activated receptor alpha.
Xu X; Ni H; Guo Y; Lin Y; Ji J; Jin C; Yuan F; Feng M; Ji N; Zheng Y; Jiang Q
Environ Pollut; 2021 Dec; 290():118112. PubMed ID: 34500398
[TBL] [Abstract][Full Text] [Related]
6. PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling.
Rosen MB; Das KP; Rooney J; Abbott B; Lau C; Corton JC
Toxicology; 2017 Jul; 387():95-107. PubMed ID: 28558994
[TBL] [Abstract][Full Text] [Related]
7. The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice.
Su S; Billy LJ; Chang S; Gonzalez FJ; Patterson AD; Peters JM
Toxicology; 2022 Jan; 465():153056. PubMed ID: 34861291
[TBL] [Abstract][Full Text] [Related]
8. Exposure to GenX and Its Novel Analogs Disrupts Hepatic Bile Acid Metabolism in Male Mice.
Guo H; Chen J; Zhang H; Yao J; Sheng N; Li Q; Guo Y; Wu C; Xie W; Dai J
Environ Sci Technol; 2022 May; 56(10):6133-6143. PubMed ID: 34427428
[TBL] [Abstract][Full Text] [Related]
9. In vitro activity of a panel of per- and polyfluoroalkyl substances (PFAS), fatty acids, and pharmaceuticals in peroxisome proliferator-activated receptor (PPAR) alpha, PPAR gamma, and estrogen receptor assays.
Evans N; Conley JM; Cardon M; Hartig P; Medlock-Kakaley E; Gray LE
Toxicol Appl Pharmacol; 2022 Aug; 449():116136. PubMed ID: 35752307
[TBL] [Abstract][Full Text] [Related]
10. Exposure to GenX and its novel analogs disrupts fatty acid metabolism in male mice.
Guo H; Sheng N; Guo Y; Wu C; Xie W; Dai J
Environ Pollut; 2021 Dec; 291():118202. PubMed ID: 34562693
[TBL] [Abstract][Full Text] [Related]
11. Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation.
McCarthy TC; Pollak PT; Hanniman EA; Sinal CJ
J Pharmacol Exp Ther; 2004 Dec; 311(3):864-73. PubMed ID: 15265979
[TBL] [Abstract][Full Text] [Related]
12. The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice.
Li X; Wang Z; Klaunig JE
Toxicology; 2019 Mar; 416():1-14. PubMed ID: 30711707
[TBL] [Abstract][Full Text] [Related]
13. Bile acid metabolism disorder mediates hepatotoxicity of Nafion by-product 2 and perfluorooctane sulfonate in male PPARα-KO mice.
Wang Z; Zang L; Ren W; Guo H; Sheng N; Zhou X; Guo Y; Dai J
Sci Total Environ; 2023 Jun; 876():162579. PubMed ID: 36870486
[TBL] [Abstract][Full Text] [Related]
14. Hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) alters maternal and fetal glucose and lipid metabolism and produces neonatal mortality, low birthweight, and hepatomegaly in the Sprague-Dawley rat.
Conley JM; Lambright CS; Evans N; McCord J; Strynar MJ; Hill D; Medlock-Kakaley E; Wilson VS; Gray LE
Environ Int; 2021 Jan; 146():106204. PubMed ID: 33126064
[TBL] [Abstract][Full Text] [Related]
15. Transcriptional pathways linked to fetal and maternal hepatic dysfunction caused by gestational exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) in CD-1 mice.
Blake BE; Miller CN; Nguyen H; Chappell VA; Phan TP; Phadke DP; Balik-Meisner MR; Mav D; Shah RR; Fenton SE
Ecotoxicol Environ Saf; 2022 Dec; 248():114314. PubMed ID: 36436258
[TBL] [Abstract][Full Text] [Related]
16. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
[TBL] [Abstract][Full Text] [Related]
17. Perfluorooctanoic acid (PFOA) and hexafluoropropylene oxide-dimer acid (GenX): Hepatic stress and bile acid metabolism with different pathways.
Yoo HJ; Pyo MC; Rhee KH; Lim JM; Yang SA; Yoo MK; Lee KW
Ecotoxicol Environ Saf; 2023 Jul; 259():115001. PubMed ID: 37196520
[TBL] [Abstract][Full Text] [Related]
18. Antiepileptic Drug-Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator-Activated Receptor
Shizu R; Otsuka Y; Ezaki K; Ishii C; Arakawa S; Amaike Y; Abe T; Hosaka T; Sasaki T; Kanno Y; Miyata M; Yamazoe Y; Yoshinari K
Mol Pharmacol; 2020 Nov; 98(5):634-647. PubMed ID: 32892155
[TBL] [Abstract][Full Text] [Related]
19. Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX).
Blake BE; Cope HA; Hall SM; Keys RD; Mahler BW; McCord J; Scott B; Stapleton HM; Strynar MJ; Elmore SA; Fenton SE
Environ Health Perspect; 2020 Feb; 128(2):27006. PubMed ID: 32074459
[TBL] [Abstract][Full Text] [Related]
20. Effects of perfluorooctanoic acid (PFOA) on gene expression profiles via nuclear receptors in HepaRG cells: Comparative study with in vitro transactivation assays.
Murase W; Kubota A; Ikeda-Araki A; Terasaki M; Nakagawa K; Shizu R; Yoshinari K; Kojima H
Toxicology; 2023 Aug; 494():153577. PubMed ID: 37302725
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
