140 related articles for article (PubMed ID: 38218889)
1. Activation of γ-globin expression by LncRNA-mediated ERF promoter hypermethylation in β-thalassemia.
Bao X; Gao Y; Wang Z; Ye Y; Chen D; Zuo Y; Zhao C; Xu X
Clin Epigenetics; 2024 Jan; 16(1):12. PubMed ID: 38218889
[TBL] [Abstract][Full Text] [Related]
2. Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.
Bao X; Zhang X; Wang L; Wang Z; Huang J; Zhang Q; Ye Y; Liu Y; Chen D; Zuo Y; Liu Q; Xu P; Huang B; Fang J; Lao J; Feng X; Li Y; Kurita R; Nakamura Y; Yu W; Ju C; Huang C; Mohandas N; Li D; Zhao C; Xu X
Am J Hum Genet; 2021 Apr; 108(4):709-721. PubMed ID: 33735615
[TBL] [Abstract][Full Text] [Related]
3. DNA methylation patterns of β-globin cluster in β-thalassemia patients.
Bao X; Zuo Y; Chen D; Zhao C
Clin Epigenetics; 2020 Dec; 12(1):187. PubMed ID: 33272312
[TBL] [Abstract][Full Text] [Related]
4. Long noncoding RNA HBBP1 enhances γ-globin expression through the ETS transcription factor ELK1.
Ma SP; Xi HR; Gao XX; Yang JM; Kurita R; Nakamura Y; Song XM; Chen HY; Lu DR
Biochem Biophys Res Commun; 2021 May; 552():157-163. PubMed ID: 33744764
[TBL] [Abstract][Full Text] [Related]
5. Reactivation of γ-globin expression using a minicircle DNA system to treat β-thalassemia.
Ma SP; Gao XX; Zhou GQ; Zhang HK; Yang JM; Wang WJ; Song XM; Chen HY; Lu DR
Gene; 2022 Apr; 820():146289. PubMed ID: 35143940
[TBL] [Abstract][Full Text] [Related]
6. BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathies.
Iftikhar F; Khan MBN; Tehreem S; Kanwal N; Musharraf SG
Bioorg Chem; 2023 Nov; 140():106768. PubMed ID: 37586133
[TBL] [Abstract][Full Text] [Related]
7. miR-30a regulates γ-globin expression in erythoid precursors of intermedia thalassemia through targeting BCL11A.
Gholampour MA; Asadi M; Naderi M; Azarkeivan A; Soleimani M; Atashi A
Mol Biol Rep; 2020 May; 47(5):3909-3918. PubMed ID: 32406020
[TBL] [Abstract][Full Text] [Related]
8. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
[TBL] [Abstract][Full Text] [Related]
9. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.
Traxler EA; Yao Y; Wang YD; Woodard KJ; Kurita R; Nakamura Y; Hughes JR; Hardison RC; Blobel GA; Li C; Weiss MJ
Nat Med; 2016 Sep; 22(9):987-90. PubMed ID: 27525524
[TBL] [Abstract][Full Text] [Related]
10. Synergistic effect of two β globin gene cluster mutations leading to the hereditary persistence of fetal hemoglobin (HPFH) phenotype.
Hariharan P; Sawant M; Gorivale M; Manchanda R; Colah R; Ghosh K; Nadkarni A
Mol Biol Rep; 2017 Oct; 44(5):413-417. PubMed ID: 28879539
[TBL] [Abstract][Full Text] [Related]
11. Trienone analogs of curcuminoids induce fetal hemoglobin synthesis via demethylation at
Nuamsee K; Chuprajob T; Pabuprapap W; Jintaridth P; Munkongdee T; Phannasil P; Vadolas J; Chaichompoo P; Suksamrarn A; Svasti S
Sci Rep; 2021 Apr; 11(1):8552. PubMed ID: 33879818
[TBL] [Abstract][Full Text] [Related]
12. Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β0-Thalassemia Families with High Fetal Hemoglobin Levels.
Bianchi N; Cosenza LC; Lampronti I; Finotti A; Breveglieri G; Zuccato C; Fabbri E; Marzaro G; Chilin A; De Angelis G; Borgatti M; Gallucci C; Alfieri C; Ribersani M; Isgrò A; Marziali M; Gaziev J; Morrone A; Sodani P; Lucarelli G; Gambari R; Paciaroni K
Mol Diagn Ther; 2016 Apr; 20(2):161-73. PubMed ID: 26897028
[TBL] [Abstract][Full Text] [Related]
13. Effects of Mithramycin on BCL11A Gene Expression and on the Interaction of the BCL11A Transcriptional Complex to γ-Globin Gene Promoter Sequences.
Finotti A; Gasparello J; Zuccato C; Cosenza LC; Fabbri E; Bianchi N; Gambari R
Genes (Basel); 2023 Oct; 14(10):. PubMed ID: 37895276
[TBL] [Abstract][Full Text] [Related]
14. Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.
Wilber A; Hargrove PW; Kim YS; Riberdy JM; Sankaran VG; Papanikolaou E; Georgomanoli M; Anagnou NP; Orkin SH; Nienhuis AW; Persons DA
Blood; 2011 Mar; 117(10):2817-26. PubMed ID: 21156846
[TBL] [Abstract][Full Text] [Related]
15. A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the γ-globin gene in β-thalassemia.
Gong Y; Zhang X; Zhang Q; Zhang Y; Ye Y; Yu W; Shao C; Yan T; Huang J; Zhong J; Wang L; Li Y; Wang L; Xu X
Blood; 2021 Mar; 137(12):1652-1657. PubMed ID: 33227819
[TBL] [Abstract][Full Text] [Related]
16. An Aγ-globin G->A gene polymorphism associated with β
Breveglieri G; Bianchi N; Cosenza LC; Gamberini MR; Chiavilli F; Zuccato C; Montagner G; Borgatti M; Lampronti I; Finotti A; Gambari R
BMC Med Genet; 2017 Aug; 18(1):93. PubMed ID: 28851297
[TBL] [Abstract][Full Text] [Related]
17. A Genetic Variant Ameliorates β-Thalassemia Severity by Epigenetic-Mediated Elevation of Human Fetal Hemoglobin Expression.
Chen D; Zuo Y; Zhang X; Ye Y; Bao X; Huang H; Tepakhan W; Wang L; Ju J; Chen G; Zheng M; Liu D; Huang S; Zong L; Li C; Chen Y; Zheng C; Shi L; Zhao Q; Wu Q; Fucharoen S; Zhao C; Xu X
Am J Hum Genet; 2017 Jul; 101(1):130-138. PubMed ID: 28669403
[TBL] [Abstract][Full Text] [Related]
18. Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.
Martyn GE; Wienert B; Yang L; Shah M; Norton LJ; Burdach J; Kurita R; Nakamura Y; Pearson RCM; Funnell APW; Quinlan KGR; Crossley M
Nat Genet; 2018 Apr; 50(4):498-503. PubMed ID: 29610478
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping.
Krivega I; Byrnes C; de Vasconcellos JF; Lee YT; Kaushal M; Dean A; Miller JL
Blood; 2015 Jul; 126(5):665-72. PubMed ID: 25979948
[TBL] [Abstract][Full Text] [Related]
20. Cilostazol-mediated reversion of γ-globin silencing is associated with a high level of HbF production: A potential therapeutic candidate for β-globin disorders.
Ali H; Khan F; Musharraf SG
Biomed Pharmacother; 2021 Oct; 142():112058. PubMed ID: 34426256
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
