BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 38219574)

  • 1. Thiol starvation triggers melanoma state switching in an ATF4 and NRF2-dependent manner.
    Meinert M; Jessen C; Hufnagel A; Kreß JKC; Burnworth M; Däubler T; Gallasch T; Xavier da Silva TN; Dos Santos AF; Ade CP; Schmitz W; Kneitz S; Friedmann Angeli JP; Meierjohann S
    Redox Biol; 2024 Apr; 70():103011. PubMed ID: 38219574
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2.
    Kreß JKC; Jessen C; Hufnagel A; Schmitz W; Xavier da Silva TN; Ferreira Dos Santos A; Mosteo L; Goding CR; Friedmann Angeli JP; Meierjohann S
    Cell Rep; 2023 Jul; 42(7):112724. PubMed ID: 37410595
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gamma-tocopheryl quinone, not alpha-tocopheryl quinone, induces adaptive response through up-regulation of cellular glutathione and cysteine availability via activation of ATF4.
    Ogawa Y; Saito Y; Nishio K; Yoshida Y; Ashida H; Niki E
    Free Radic Res; 2008 Jul; 42(7):674-87. PubMed ID: 18654882
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nrf2- and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition.
    Ye P; Mimura J; Okada T; Sato H; Liu T; Maruyama A; Ohyama C; Itoh K
    Mol Cell Biol; 2014 Sep; 34(18):3421-34. PubMed ID: 25002527
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis.
    He F; Zhang P; Liu J; Wang R; Kaufman RJ; Yaden BC; Karin M
    J Hepatol; 2023 Aug; 79(2):362-377. PubMed ID: 36996941
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutation of ATF4 mediates resistance of neuronal cell lines against oxidative stress by inducing xCT expression.
    Lewerenz J; Sato H; Albrecht P; Henke N; Noack R; Methner A; Maher P
    Cell Death Differ; 2012 May; 19(5):847-58. PubMed ID: 22095285
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The proteasome inhibitor lactacystin enhances GSH synthesis capacity by increased expression of antioxidant components in an Nrf2-independent, but p38 MAPK-dependent manner in rat colorectal carcinoma cells.
    Huseby NE; Ravuri C; Moens U
    Free Radic Res; 2016; 50(1):1-13. PubMed ID: 26530909
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Redox status in mammalian cells and stem cells during culture in vitro: critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance.
    Ishii T; Mann GE
    Redox Biol; 2014; 2():786-94. PubMed ID: 25009780
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress.
    Habib E; Linher-Melville K; Lin HX; Singh G
    Redox Biol; 2015 Aug; 5():33-42. PubMed ID: 25827424
    [TBL] [Abstract][Full Text] [Related]  

  • 10. AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells.
    Cahuzac KM; Lubin A; Bosch K; Stokes N; Shoenfeld SM; Zhou R; Lemon H; Asara J; Parsons RE
    Cell Rep; 2023 May; 42(5):112536. PubMed ID: 37210723
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
    Liu Z; Dong W; Yang B; Peng L; Xia X; Pu L; Zhang N; Song E; Song Y
    Chem Res Toxicol; 2018 Nov; 31(11):1230-1239. PubMed ID: 30358983
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of Nrf2 in bone marrow-derived macrophages impairs antigen-driven CD8(+) T cell function by limiting GSH and Cys availability.
    Sha LK; Sha W; Kuchler L; Daiber A; Giegerich AK; Weigert A; Knape T; Snodgrass R; Schröder K; Brandes RP; Brüne B; von Knethen A
    Free Radic Biol Med; 2015 Jun; 83():77-88. PubMed ID: 25687825
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biological insights in non-small cell lung cancer.
    Rosell R; Jain A; Codony-Servat J; Jantus-Lewintre E; Morrison B; Ginesta JB; González-Cao M
    Cancer Biol Med; 2023 Jun; 20(7):500-18. PubMed ID: 37381723
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression.
    Jessen C; Kreß JKC; Baluapuri A; Hufnagel A; Schmitz W; Kneitz S; Roth S; Marquardt A; Appenzeller S; Ade CP; Glutsch V; Wobser M; Friedmann-Angeli JP; Mosteo L; Goding CR; Schilling B; Geissinger E; Wolf E; Meierjohann S
    Oncogene; 2020 Oct; 39(44):6841-6855. PubMed ID: 32978520
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nrf2 protects human lens epithelial cells against H
    Ma TJ; Lan DH; He SZ; Ye Z; Li P; Zhai W; Chen WQ; Huang Y; Fu Y; Sun A; Wang YB; Ye Z; Li JL; Gao Y; Yan XL; Li ZH
    Exp Eye Res; 2018 Apr; 169():28-37. PubMed ID: 29421327
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals.
    Torrence ME; MacArthur MR; Hosios AM; Valvezan AJ; Asara JM; Mitchell JR; Manning BD
    Elife; 2021 Mar; 10():. PubMed ID: 33646118
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner.
    Chen D; Fan Z; Rauh M; Buchfelder M; Eyupoglu IY; Savaskan N
    Oncogene; 2017 Oct; 36(40):5593-5608. PubMed ID: 28553953
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 4-Hydroperoxy-2-decenoic acid ethyl ester protects against 6-hydroxydopamine-induced cell death via activation of Nrf2-ARE and eIF2α-ATF4 pathways.
    Inoue Y; Hara H; Mitsugi Y; Yamaguchi E; Kamiya T; Itoh A; Adachi T
    Neurochem Int; 2018 Jan; 112():288-296. PubMed ID: 28823537
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes.
    Mimura J; Inose-Maruyama A; Taniuchi S; Kosaka K; Yoshida H; Yamazaki H; Kasai S; Harada N; Kaufman RJ; Oyadomari S; Itoh K
    Int J Mol Sci; 2019 Apr; 20(7):. PubMed ID: 30959808
    [No Abstract]   [Full Text] [Related]  

  • 20. Differences in cell death in methionine versus cysteine depletion.
    Wallis KF; Morehead LC; Bird JT; Byrum SD; Miousse IR
    Environ Mol Mutagen; 2021 Mar; 62(3):216-226. PubMed ID: 33615565
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.