169 related articles for article (PubMed ID: 38229201)
1. BMP-ACVR1 Axis is Critical for Efficacy of PRC2 Inhibitors in B-Cell Lymphoma.
Liu D; Li Z; Tan D; An Y; Chu L; Chen T; Li W; Zhou A; Xiang R; Zhang L; Qu Y; Qi W
Adv Sci (Weinh); 2024 Mar; 11(12):e2306499. PubMed ID: 38229201
[TBL] [Abstract][Full Text] [Related]
2. EZH2 W113C is a gain-of-function mutation in B-cell lymphoma enabling both PRC2 methyltransferase activation and tazemetostat resistance.
Chu L; Tan D; Zhu M; Qu Y; Ma X; Song BL; Qi W
J Biol Chem; 2023 Apr; 299(4):103073. PubMed ID: 36858198
[TBL] [Abstract][Full Text] [Related]
3. Reduced GS Domain Serine/Threonine Requirements of Fibrodysplasia Ossificans Progressiva Mutant Type I BMP Receptor ACVR1 in the Zebrafish.
Allen RS; Jones WD; Hale M; Warder BN; Shore EM; Mullins MC
J Bone Miner Res; 2023 Sep; 38(9):1364-1385. PubMed ID: 37329499
[TBL] [Abstract][Full Text] [Related]
4. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling.
Barruet E; Morales BM; Lwin W; White MP; Theodoris CV; Kim H; Urrutia A; Wong SA; Srivastava D; Hsiao EC
Stem Cell Res Ther; 2016 Aug; 7(1):115. PubMed ID: 27530160
[TBL] [Abstract][Full Text] [Related]
5. Targeting EZH2 and PRC2 dependence as novel anticancer therapy.
Xu B; Konze KD; Jin J; Wang GG
Exp Hematol; 2015 Aug; 43(8):698-712. PubMed ID: 26027790
[TBL] [Abstract][Full Text] [Related]
6. Variant BMP receptor mutations causing fibrodysplasia ossificans progressiva (FOP) in humans show BMP ligand-independent receptor activation in zebrafish.
Mucha BE; Hashiguchi M; Zinski J; Shore EM; Mullins MC
Bone; 2018 Apr; 109():225-231. PubMed ID: 29307777
[TBL] [Abstract][Full Text] [Related]
7. Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway.
Omi M; Kaartinen V; Mishina Y
J Biol Chem; 2019 Nov; 294(47):17818-17836. PubMed ID: 31619522
[TBL] [Abstract][Full Text] [Related]
8. EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations.
McCabe MT; Ott HM; Ganji G; Korenchuk S; Thompson C; Van Aller GS; Liu Y; Graves AP; Della Pietra A; Diaz E; LaFrance LV; Mellinger M; Duquenne C; Tian X; Kruger RG; McHugh CF; Brandt M; Miller WH; Dhanak D; Verma SK; Tummino PJ; Creasy CL
Nature; 2012 Dec; 492(7427):108-12. PubMed ID: 23051747
[TBL] [Abstract][Full Text] [Related]
9. Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1.
Kamiya N; Kaartinen VM; Mishina Y
Biochem Biophys Res Commun; 2011 Oct; 414(2):326-30. PubMed ID: 21945937
[TBL] [Abstract][Full Text] [Related]
10. Molecular consequences of the ACVR1(R206H) mutation of fibrodysplasia ossificans progressiva.
Song GA; Kim HJ; Woo KM; Baek JH; Kim GS; Choi JY; Ryoo HM
J Biol Chem; 2010 Jul; 285(29):22542-53. PubMed ID: 20463014
[TBL] [Abstract][Full Text] [Related]
11. Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1
Wentworth KL; Lalonde RL; Groppe JC; Brewer N; Moody T; Hansberry S; Taylor KE; Shore EM; Kaplan FS; Pignolo RJ; Yelick PC; Hsiao EC
J Bone Miner Res; 2022 Nov; 37(11):2058-2076. PubMed ID: 36153796
[TBL] [Abstract][Full Text] [Related]
12. AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.
Thomas PS; Rajderkar S; Lane J; Mishina Y; Kaartinen V
Dev Biol; 2014 Jun; 390(2):191-207. PubMed ID: 24680892
[TBL] [Abstract][Full Text] [Related]
13. The Fibrodysplasia Ossificans Progressiva (FOP) mutation p.R206H in ACVR1 confers an altered ligand response.
Hildebrand L; Stange K; Deichsel A; Gossen M; Seemann P
Cell Signal; 2017 Jan; 29():23-30. PubMed ID: 27713089
[TBL] [Abstract][Full Text] [Related]
14. Dysregulated BMP signaling through ACVR1 impairs digit joint development in fibrodysplasia ossificans progressiva (FOP).
Towler OW; Peck SH; Kaplan FS; Shore EM
Dev Biol; 2021 Feb; 470():136-146. PubMed ID: 33217406
[TBL] [Abstract][Full Text] [Related]
15. Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish.
Allen RS; Tajer B; Shore EM; Mullins MC
Elife; 2020 Sep; 9():. PubMed ID: 32897189
[TBL] [Abstract][Full Text] [Related]
16. Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop.
Aykul S; Corpina RA; Goebel EJ; Cunanan CJ; Dimitriou A; Kim HJ; Zhang Q; Rafique A; Leidich R; Wang X; McClain J; Jimenez J; Nannuru KC; Rothman NJ; Lees-Shepard JB; Martinez-Hackert E; Murphy AJ; Thompson TB; Economides AN; Idone V
Elife; 2020 Jun; 9():. PubMed ID: 32515349
[TBL] [Abstract][Full Text] [Related]
17. PRC2-mediated repression of SMARCA2 predicts EZH2 inhibitor activity in SWI/SNF mutant tumors.
Januario T; Ye X; Bainer R; Alicke B; Smith T; Haley B; Modrusan Z; Gould S; Yauch RL
Proc Natl Acad Sci U S A; 2017 Nov; 114(46):12249-12254. PubMed ID: 29087303
[TBL] [Abstract][Full Text] [Related]
18. Elevated BMP and Mechanical Signaling Through YAP1/RhoA Poises FOP Mesenchymal Progenitors for Osteogenesis.
Stanley A; Heo SJ; Mauck RL; Mourkioti F; Shore EM
J Bone Miner Res; 2019 Oct; 34(10):1894-1909. PubMed ID: 31107558
[TBL] [Abstract][Full Text] [Related]
19. Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma.
Kwok HS; Freedy AM; Siegenfeld AP; Morriss JW; Waterbury AL; Kissler SM; Liau BB
Nat Chem Biol; 2023 Sep; 19(9):1105-1115. PubMed ID: 36973442
[TBL] [Abstract][Full Text] [Related]
20. Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma.
Lee SC; Phipson B; Hyland CD; Leong HS; Allan RS; Lun A; Hilton DJ; Nutt SL; Blewitt ME; Smyth GK; Alexander WS; Majewski IJ
Blood; 2013 Oct; 122(15):2654-63. PubMed ID: 23982173
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
